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Relating Hyperbaric Oxygen Therapy and Barotraumatism Occurrence: A Linear Model Approach

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Computational Science and Its Applications – ICCSA 2018 (ICCSA 2018)


Hyperbaric oxygen therapy is a therapeutic modality that allows an increase of perfusion of \(O_2\) in tissues reducing edema and tissue hypoxia, aiding the treatment of ischemia and infection [1, 2]. Some complications of this therapy can happen, the middle ear barotraumatism is the most frequent.

The objectives of this study are to determine incidence and severity and to identify predictors of risk for barotraumatism of the middle ear in a large population of patients undergoing routine hyperbaric oxygen therapy.

This work studied the clinical characteristics of 1732 patients who underwent treatment at the Portuguese Navy’s Center for Underwater and Hyperbaric Medicine between 2012 and 2016, in order to better characterize this issue with regard to incidence, severity and recurrence such as age, sex, clinical indication for hyperbaric oxygen therapy, personal history of allergic rhinitis and symptomatology of nasal obstruction at the time of the occurrence. Several statistical techniques such as analysis of variance and generalized linear models were applied.

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  1. 1.

    The ata unit (atmosphere absolute) is used in place of atmosphere (atm) to indicate that the pressure shown is the total ambient pressure of the system, compared to vacuum, being calculated or measured. For example, for underwater pressures, a pressure of 3.1 ata would mean that the 1 atm of the air above water is included in this value and the pressure due to water would total 2.1 atm. Adapted from definition in [3].

  2. 2.

    “The classification system for tympanograms commonly used today was developed by Liden [12] and Jerger [13]. There are three main types of tympanograms: A, B, and C. Type A tympanograms look like a teepee, and indicate a normal middle ear system, free of fluid or physiological anomalies which would prevent the admittance of sound from the middle ear into the cochlea. Type B tympanograms are a flat line, which is consistent with middle ear pathology, such as fluid or infection behind the ear drum. In some cases, these tympanograms are seen when there is a hole in the ear drum; the difference lies in the ear canal volume: a larger ear canal volume indicates a perforation in the ear drum. Type C tympanograms are still shaped like a teepee, but are shifted negatively on the graph. This indicates negative pressure in the middle ear space, often consistent with sinus or allergy congestion, or the end-stages of a cold or ear infection.”


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This work was supported by Portuguese funds through the Center for Computational and Stochastic Mathematics (CEMAT), The Portuguese Foundation for Science and Technology (FCT), University of Lisbon, Portugal, project UID/Multi/04621/2013, and Center of Naval Research (CINAV), Naval Academy, Portuguese Navy, Portugal.

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Correspondence to M. Filomena Teodoro .

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Teodoro, M.F., Teles, S.S., Marques, M.C., Guerreiro, F.G. (2018). Relating Hyperbaric Oxygen Therapy and Barotraumatism Occurrence: A Linear Model Approach. In: Gervasi, O., et al. Computational Science and Its Applications – ICCSA 2018. ICCSA 2018. Lecture Notes in Computer Science(), vol 10961. Springer, Cham.

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