Occult Macular Dystrophy

  • Stephen H. Tsang
  • Tarun SharmaEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1085)


Patients with occult macular dystrophy (OMD) are usually middle-aged and have progressive loss of central vision or notice central scotoma, but no significant abnormality is seen in the fundus or fluorescein angiography. Optical coherence tomography (OCT) shows loss of the ellipsoid band in the central area (Fig. 19.1). Full-field electroretinography (ERG) is normal or may show diminished cone response; multifocal ERG reveals diminished amplitude in the central retina.


Autosomal dominant Occult macular dystrophy 

Suggested Reading

  1. Ahn SJ, Cho SI, Ahn J, Park SS, Park KH, Woo SJ. Clinical and genetic characteristics of Korean occult macular dystrophy patients. Invest Ophthalmol Vis Sci. 2013;54:4856–63.CrossRefGoogle Scholar
  2. Hayashi T, Gekka T, Kozaki K, Ohkuma Y, Tanaka I, Yamada H, Tsuneoka H. Autosomal dominant occult macular dystrophy with an RP1L1 mutation (R45W). Optom Vis Sci. 2012;89:684–91.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Jonas Children’s Vision Care, Bernard & Shirlee Brown Glaucoma Laboratory, Columbia Stem Cell Initiative-Departments of Ophthalmology, Biomedical Engineering, Pathology & Cell Biology, Institute of Human Nutrition, Vagelos College of Physicians and Surgeons, Columbia UniversityNew YorkUSA
  2. 2.Department of Ophthalmology, Columbia UniversityEdward S. Harkness Eye Institute, NewYork-Presbyterian HospitalNew YorkUSA

Personalised recommendations