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Particles and Nanoparticles in Pharmaceutical Products pp 429–443Cite as

The Side Effects of Drugs: Nanopathological Hazards and Risks

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Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series ((AAPS,volume 29))

Abstract

Drugs are aimed at the prevention or treatment of diseases, but their positive effect cannot be guaranteed in any case. The chapter describes a few clinical cases of diseases contracted by the patient from particulate contaminants contained as foreign bodies in the drug either as such or in the form of their precursors. The cases were studied analysing the biopsic pathological samples by means of a scanning electron microscope coupled with an X-ray microprobe of an energy dispersive system. Once the foreign bodies are identified, an anamnestic work is performed to trace them in the patient’s environment and lifestyle, including the drugs he/she takes.

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Author information

Authors and Affiliations

  1. President of Health, Law and Science Association, Quai du Sujeut 16-18, Geneva, Switzerland

    Antonietta M. Gatti & Stefano Montanari

  2. Nanodiagnostics, via E. Fermi 1L, 41051, San Vito, MO, Italy

    Antonietta M. Gatti

Authors
  1. Antonietta M. Gatti
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  2. Stefano Montanari
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Corresponding author

Correspondence to Antonietta M. Gatti .

Editor information

Editors and Affiliations

  1. Pijnacker, Zuid-Holland, The Netherlands

    Henk G. Merkus

  2. Delft, Zuid-Holland, The Netherlands

    Gabriel M. H. Meesters

  3. Hilversum, Noord-Holland, The Netherlands

    Wim Oostra

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© 2018 American Association of Pharmaceutical Scientists

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Gatti, A.M., Montanari, S. (2018). The Side Effects of Drugs: Nanopathological Hazards and Risks. In: Merkus, H., Meesters, G., Oostra, W. (eds) Particles and Nanoparticles in Pharmaceutical Products. AAPS Advances in the Pharmaceutical Sciences Series, vol 29. Springer, Cham. https://doi.org/10.1007/978-3-319-94174-5_13

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