Abstract
This chapter covers the study of human epidemiology, including family studies in genetic epidemiology, linkage analysis, genetic Mapping in human diseases, human genetic influences on diseases, genetic relationships in familial aggregation, and derivation of familial risk.
An Illustration is provided of a research project in genetic epidemiology research which included
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(1)
Heritability Analysis
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(2)
Molecular Variation Study Methods
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(3)
Genomics for Human Genetic Epidemiology
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Complex Traits and Mendelian Inheritance
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Mendel’s Laws
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Hardy-Weinberg Principle
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Gene Structure and Genetic Code
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Genetic Linkage and Linkage Disequilibrium
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Study Designs for of Rare Genetic Variations
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Spectrum of Variation
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Familial Factors in Human Genetic Epidemiology
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*Human Genetic Association
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Genetic Epidemiology Owing to Population Stratification
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Environmental Effects on Genetic Epidemiology
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Genetic Epidemiology and Public Health
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Chan, B.K.C. (2018). Applied Human Genetic Epidemiology. In: Biostatistics for Human Genetic Epidemiology. Advances in Experimental Medicine and Biology, vol 1082. Springer, Cham. https://doi.org/10.1007/978-3-319-93791-5_4
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DOI: https://doi.org/10.1007/978-3-319-93791-5_4
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