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Neonatal Surgery pp 485–489Cite as

Wilms Tumor in Neonates

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Abstract

Wilms tumor (WT) or nephroblastoma is the second commonest neonatal renal tumor accounting for 20% of cases and represents the most important renal malignancy during childhood. This neoplasm develops from the primitive metanephric blastema, the primitive tissue of normal kidney, but it may be formed also by cell of nonrenal tissues. In neonates affected by nephroblastoma, only 16% of these are being diagnosed antenatally, and the rest are identified during investigation for maternal polyhydramnios, hydrops fetalis, or other congenital anomalies. Wilms tumor occurs in males and females equally, and in 1% of cases, there is a family history, and it is associated with various congenital syndromes [1, 2]. A recent AIEOP study reports that infants have a good prognosis than older children affected by WT because of a biological diversity and an earlier diagnosis occurring during screening test administered for the study of genitourinary abnormalities or genetic syndromes associated to early infancy [3].

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Author information

Authors and Affiliations

  1. Department of Pediatric Hematology Oncology, Sant’Orsola-Malpighi University Hospital, Bologna, Italy

    Matteo Carella, Riccardo Masetti & Andrea Pession

  2. Department of Pediatric Surgery, Sant’Orsola-Malpighi University Hospital, Bologna, Italy

    Claudio Antonellini & Beatrice Randi

Authors
  1. Matteo Carella
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  2. Riccardo Masetti
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  3. Claudio Antonellini
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  4. Beatrice Randi
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  5. Andrea Pession
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Corresponding author

Correspondence to Andrea Pession .

Editor information

Editors and Affiliations

  1. Pediatric Surgery, S.Orsola Hospital, University of Bologna, Bologna, Italy

    Mario Lima

  2. Pediatric Surgeon FMH EBPS, Lausanne-Pully, Switzerland

    Olivier Reinberg

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Carella, M., Masetti, R., Antonellini, C., Randi, B., Pession, A. (2019). Wilms Tumor in Neonates. In: Lima, M., Reinberg, O. (eds) Neonatal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-93534-8_37

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  • DOI: https://doi.org/10.1007/978-3-319-93534-8_37

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-93532-4

  • Online ISBN: 978-3-319-93534-8

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