Abstract
AVNRT is the most frequent form of paroxysmal supraventricular tachycardia. In French the term is TRIN (tachycardie par reentre intra-nodale) and in English AVNRT (atrioventricular node reentrant tachycardia). It can be induced in the EP lab by atrial or ventricular stimulation in the basal state or after drug administration. The drug of choice is isoprenaline, but in some European countries, the lack of the drug produced efforts to search for another options. There is no study that compares efficacy of atropine versus adrenaline for AVNRT induction in the EP lab. In our study, we compared the two drugs in terms of efficacy and side effects. The investigators hypothesized that adrenaline would be a better and more convenient for the induction of arrhythmias since adrenaline is administered as an intravenous infusion over several minutes, in comparison to atropine, which is administered as a bolus. We demonstrated our hypothesis by statistical analysis.
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References
Akhtar M, Damato AN, Batsford WP, Caracta AR, Ruskin JN, Weisfogel GM, et al. Induction of atrioventricular nodal reentrant tachycardia after atropine. Report of five cases. Am J Cardiol. 1975;36:286–91.
Hariman RJ, Gomes JA, El-Sherif N. Catecholamine- dependent atrioventricular nodal reentrant tachycardia. Circulation. 1983;67:681–6.
Wu D. A-V nodal reentry. Pacing Clin Electrophysiol. 1983;6:1190–200.
Kim YH, Leitch JW, Klein GJ, Yee R, Leather RA. Effect of atropine and isoproterenol on tachycardia induction in asymptomatic patients with Wolff- Parkinson-White electrocardiographic pattern. Can J Cardiol. 1992;8:716–20.
Cismaru G, Rosu R, Muresan L, Puiu M, Andronache M, Hengan E, et al. The value of adrenaline in the induction of supraventricular tachycardia in the EP lab. Europace. 2014;16:1634–8.
Toda I, Kawahara T, Murakawa Y, Nozaki A, Kawakubo K, Inoue H, et al. Electrophysiological study of young patients with exercise related paroxysmal of palpitation: role of atropine and isoprenaline for initiation of supraventricular tachycardia. Br Heart J. 1989;61:268–73.
Huycke EC, Lai WT, Nguyen NX, Keung EC, Sung RJ. Role of intravenous isoproterenol in the electrophysiological induction of atrioventricular node reentrant tachycardia in patients with dual atrioventricular node pathways. Am J Cardiol. 1989;64(18):1131–7.
Brembilla- Perrot B, Terrier de la Chaise A, Pichene M, Aliot E, Cherrier F, Pernot C. Isoprenaline as an aid to the induction of catecholamine dependent supraventricular tachycardia during programmed stimulation. Br Heart J. 1989;61:348–55.
Stellbrink C, Diem B, Schauerte P, Brehmer K, Schuett H, Hanrath P. Differential effects of atropine and isoproterenol on inducibility of atrioventricular nodal reentrant tachycardia. J Interv Card Electrophysiol. 2001;5:463–9.
Katz DF, Hegeman TW, Aleong R. Use of isoproterenol for assessment of anterograde accessory pathway conduction properties in sedated asymptomatic patients with ventricular pre-excitation. J Innov Cardiac Rhythm Manage. 2013;4:1428–33.
Oral H, Crawford T, Frederick M, Gadeela N, Wimmer A, Dey S, et al. Inducibility of paroxysmal atrial fibrillation by isoproterenol and its relation to the mode of onset of atrial fibrillation. J Cardiovasc Electrophysiol. 2008;19:466–70.
Katritsis DG, Camm AJ. Classification and differential diagnosis of atrio-ventricular nodal reentrant tachycardia. Europace. 2006;8:29–36.
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Asamoah, J. (2019). Adrenaline Versus Atropine for AVNRT Induction. In: Cismaru, G. (eds) Arrhythmia Induction in the EP Lab. Springer, Cham. https://doi.org/10.1007/978-3-319-92729-9_10
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DOI: https://doi.org/10.1007/978-3-319-92729-9_10
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