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Herpes Simplex and Varicella Zoster Virus

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Meningitis and Encephalitis

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Abstract

Herpes simplex virus (HSV) and varicella zoster virus (VZV) are DNA viruses in the family Herpesviridae, subfamily Alphaherpesvirinae. These viruses are common causes of human mucocutaneous infections and, although central nervous system (CNS) infection occurs in only a minority of cases, are among the most common causes of meningoencephalitis in the United States [1]. The spectrum of CNS disease for both HSV and VZV ranges from a mild, self-limited meningitis to fulminant and sometimes fatal encephalitis. While these viruses share many commonalities, the epidemiology, clinical presentation, and, to some extent, treatment are distinct; therefore HSV and VZV CNS infections will be discussed separately in this chapter.

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  1. Vanderbilt University Medical Center, Department of Infectious Diseases, Nashville, TN, USA

    Karen C. Bloch MD, MPH

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  1. UT Health-McGovern Medical School, Houston, Texas, USA

    Rodrigo Hasbun

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Bloch, K.C. (2018). Herpes Simplex and Varicella Zoster Virus. In: Hasbun, R. (eds) Meningitis and Encephalitis. Springer, Cham. https://doi.org/10.1007/978-3-319-92678-0_9

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  • DOI: https://doi.org/10.1007/978-3-319-92678-0_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-92677-3

  • Online ISBN: 978-3-319-92678-0

  • eBook Packages: MedicineMedicine (R0)

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