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Atypical Breast Proliferative Lesions and Benign Breast Disease pp 79–88Cite as

Diagnostic Management of the Atypical Hyperplasias: Core Biopsy Alone Versus Excisional Biopsy

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Abstract

Atypical ductal hyperplasia (ADH) and atypical lobular hyperplasia (ALH) are two indeterminate lesions found on breast core needle biopsy (CNB). These lesions have the potential to upstage to carcinoma on excisional biopsy. A number of studies have attempted to identify factors that may be associated with a low rate of upgrading to malignancy, thereby allowing conservative management to avoid unnecessary surgery. Patients with ADH on CNB continue to have a substantial risk of upgrade. In contrast, some patients with ALH on CNB with concordant pathologic, radiologic, and clinical information have a relatively low risk of upstaging on excision. Therefore, patients with ADH on CNB must be excised while a discussion of the risks and benefits are recommended for patients diagnosed with ALH.

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Authors and Affiliations

  1. Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Emily Siegel M.D. & Alice Chung M.D.

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  1. Emily Siegel M.D.
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  2. Alice Chung M.D.
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Correspondence to Alice Chung M.D. .

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Editors and Affiliations

  1. Samuel Oschin Comprehensive Cancer Inst, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Farin Amersi

  2. School of Medicine, University of Washington School of Medicine, Seattle, WA, USA

    Kristine Calhoun

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Siegel, E., Chung, A. (2018). Diagnostic Management of the Atypical Hyperplasias: Core Biopsy Alone Versus Excisional Biopsy. In: Amersi, F., Calhoun, K. (eds) Atypical Breast Proliferative Lesions and Benign Breast Disease . Springer, Cham. https://doi.org/10.1007/978-3-319-92657-5_6

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  • DOI: https://doi.org/10.1007/978-3-319-92657-5_6

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