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Surgical Treatment of Ductal Carcinoma In Situ

  • Meghan R. Flanagan
  • Kimberly J. Van ZeeEmail author
Chapter

Abstract

DCIS comprises approximately 25% of breast cancers diagnosed in the United States. All treatments result in excellent survival, but local recurrence rates vary dramatically. Mastectomy is associated with extremely low recurrence, and five randomized controlled trials have shown that radiation following breast conservation decreases the risk of local recurrence by half. Various combinations of clinicopathologic factors are also associated with lower risk of recurrence, but there is no subset of DCIS patients that does not experience a significant risk reduction with radiation. Each woman with DCIS deserves a careful discussion of the various treatment options, including accurate recurrence risk estimates and the relative importance to her of the risks and benefits of each option, to help her choose the optimal treatment for her.

Keywords

Breast cancer Ductal carcinoma in situ (DCIS) Surgical treatment Mastectomy Breast-conserving surgery (BCS) Adjuvant radiation Local recurrence Recurrence risk estimation Nomogram Risk models 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Breast Service, Department of SurgeryMemorial Sloan Kettering Cancer CenterNew YorkUSA

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