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Tufted Angioma and Kaposiform Hemangioendothelioma

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Evidence-Based Management of Head and Neck Vascular Anomalies

Abstract

Tufted angiomas (TA) and kaposiform hemangioendothelioma (KHE) are classified as benign vascular tumors with locally aggressive potential. They share many similar histologic and clinical features and are believed to be two entities that lie along a spectrum (Le et al, Am J Surg Pathol 34:1563–1573, 2010; Osio et al, Arch Dermatol 146:758–763, 2010). Within the same tumor, there are focal areas of both KHE and TA histopathologic phenotype, and longitudinal transformation from TA to KHE has been described (Chu et al, Dermatology 206:334–337, 2003). A unique feature of these tumors is their potential to develop a severe, life-threatening coagulopathy called Kasabach-Merritt phenomenon (KMP) (Croteau SE and Gupta D, Semin Cutan Med Surg 35:147–52, 2016).

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Authors and Affiliations

  1. Division of Dermatology, Department of Pediatrics, University of Washington, Seattle Children’s Hospital, Seattle, WA, USA

    Deepti Gupta MD

  2. Division of Hematology-Oncology, Department of Pediatrics, University of Washington, Seattle Children’s Hospital, Seattle, WA, USA

    Amy Geddis MD, PhD

  3. Department of Otolaryngology, Children’s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA

    Robert Chun MD

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  1. Deepti Gupta MD
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  2. Amy Geddis MD, PhD
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Correspondence to Robert Chun MD .

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Editors and Affiliations

  1. Otolaryngology-Head and Neck Surgery, University of Washington, Seattle Children’s Hospital, Seattle, WA, USA

    Jonathan A. Perkins

  2. Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA

    Karthik Balakrishnan

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Gupta, D., Geddis, A., Chun, R. (2018). Tufted Angioma and Kaposiform Hemangioendothelioma. In: Perkins, J., Balakrishnan, K. (eds) Evidence-Based Management of Head and Neck Vascular Anomalies. Springer, Cham. https://doi.org/10.1007/978-3-319-92306-2_9

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  • DOI: https://doi.org/10.1007/978-3-319-92306-2_9

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