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Polynomial-Time Algorithms for Phylogenetic Inference Problems

  • Leo van IerselEmail author
  • Remie Janssen
  • Mark Jones
  • Yukihiro Murakami
  • Norbert Zeh
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 10849)

Abstract

A common problem in phylogenetics is to try to infer a species phylogeny from gene trees. We consider different variants of this problem. The first variant, called Unrestricted Minimal Episodes Inference, aims at inferring a species tree based on a model of speciation and duplication where duplications are clustered in duplication episodes. The goal is to minimize the number of such episodes. The second variant, Parental Hybridization, aims at inferring a species network based on a model of speciation and reticulation. The goal is to minimize the number of reticulation events. It is a variant of the well-studied Hybridization Number problem with a more generous view on which gene trees are consistent with a given species network. We show that these seemingly different problems are in fact closely related and can, surprisingly, both be solved in polynomial time, using a structure we call “beaded trees”. However, we also show that methods based on these problems have to be used with care because the optimal species phylogenies always have some restricted form. We discuss several possibilities to overcome this problem.

Keywords

Phylogenetic inference problems Polynomial-time algorithms 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Leo van Iersel
    • 1
    Email author
  • Remie Janssen
    • 1
  • Mark Jones
    • 1
  • Yukihiro Murakami
    • 1
  • Norbert Zeh
    • 2
  1. 1.Delft Institute of Applied MathematicsDelft University of TechnologyDelftThe Netherlands
  2. 2.Faculty of Computer ScienceDalhousie UniversityHalifaxCanada

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