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Changes in Spinal Muscle Oxygenation and Perfusion During the Biering-Sørensen Test: Preliminary Results of a Study Employing NIRS-Based Muscle Oximetry

  • Andrea Vrana
  • Felix Scholkmann
  • Brigitte Wirth
  • Martin Flueck
  • Barry Kim Humphreys
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1072)

Abstract

Low back pain (LBP) is suggested to be related to deconditioning of back muscles by a decreased capacity for hyperemia in exercising muscles. However, only inconsistent evidence exists regarding back muscle perfusion and oxygen saturation in healthy subjects and patients suffering from (chronic) LBP. Aim: We measured muscle perfusion in healthy subjects during the Biering-Sørensen (BS) test (the gold standard for evaluating back muscle endurance) using a commercial near-infrared spectroscopy (NIRS) device. We analysed data sets of five female healthy subjects (age: 34 ± 15 years) who reached the maximum of 4 min during the BS test. Muscle oxygenation (SmO2) and perfusion ([tHb]) were measured using the Moxy NIRS device (Fortiori Design LLC, Hutchinson, USA). Probes were set unilaterally on M. longissimus, M. iliocostalis and M. multifidus. Additionally, mean arterial blood pressure (MAP), pulse pressure (PP), heart rate (HR), arterial oxygen saturation (SpO2) and lactate (pre, task, post) were measured. We observed (i) a large inter-subject variability in the SmO2 and [tHb] responses in the three muscles (i.e., SmO2 desaturations in the in M. longissimus across subjects during the task ranging from 1.1% to −56.6%), and (ii) a consistent response of the systemic signals in all subjects (i.e., increase in MAP, PP and HR). Lactate changes (post task minus task period) correlated with changes in PP and SmO2 of the multifidus muscle. Our preliminary results showed that during the BS test the response in the peripheral muscles was more variable than the central systemic response. A goal for future investigations is to explain this variability in the periphery by considering, for example, subject-specific changes in systemic cardiovascular activity, lactate and in the microvascular perfusion of muscle tissue.

Notes

Acknowledgments

We gratefully acknowledge funding by the Foundation for the Education of Chiropractors in Switzerland.

References

  1. 1.
    Murray CJ, Barber RM, Foreman KJ et al (2015) Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition. Lancet 386(10009):2145–2191CrossRefPubMedGoogle Scholar
  2. 2.
    Smeets RJ, Wade D, Hidding A et al (2006) The association of physical deconditioning and chronic low back pain: a hypothesis-oriented systematic review. Disabil Rehabil 28(11):673–693CrossRefPubMedGoogle Scholar
  3. 3.
    Kovacs KM, Marras WS, Litsky AS et al (2001) Localized oxygen use of healthy and low back pain individuals during controlled trunk movements. J Spinal Disord 14(2):150–158CrossRefPubMedGoogle Scholar
  4. 4.
    Kell RT, Bhambhani Y (2006) Relationship between erector spinae static endurance and muscle oxygenation-blood volume changes in healthy and low back pain subjects. Eur J Appl Physiol 96(3):241–248CrossRefPubMedGoogle Scholar
  5. 5.
    Kankaanpaa M, Colier WN, Taimela S et al (2005) Back extensor muscle oxygenation and fatigability in healthy subjects and low back pain patients during dynamic back extension exertion. Pathophysiology 12(4):267–273CrossRefPubMedGoogle Scholar
  6. 6.
    Kauppila LI (2009) Atherosclerosis and disc degeneration/low-back pain – a systematic review. Eur J Vasc Endovasc Surg 37(6):661–670CrossRefPubMedGoogle Scholar
  7. 7.
    Biering-Sorensen F (1984) Physical measurements as risk indicators for low-back trouble over a one-year period. Spine (Phila Pa 1976) 9(2):106–119CrossRefGoogle Scholar
  8. 8.
    Wang L, JacquesL Zheng SL (1995) MCML – Monte Carlo modeling of light transport in multi-layered tissues. Comput Methods Prog Biomed 47(2):131–146CrossRefGoogle Scholar
  9. 9.
    Albert WJ, Sleivert GG, Neary JP et al (2004) Monitoring individual erector spinae fatigue responses using electromyography and near infrared spectroscopy. Can J Appl Physiol 29(4):363–378CrossRefPubMedGoogle Scholar
  10. 10.
    Piiper J (2000) Perfusion, diffusion and their heterogeneities limiting blood-tissue O2 transfer in muscle. Acta Physiol Scand 168(4):603–607CrossRefPubMedGoogle Scholar
  11. 11.
    Hicks A, McGillRL Hughson S (1999) Tissue oxygenation by near-infrared spectroscopy and muscle blood flow during isometric contractions of the forearm. Can J Appl Physiol 24(3):216–230CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Andrea Vrana
    • 1
  • Felix Scholkmann
    • 2
    • 3
  • Brigitte Wirth
    • 1
  • Martin Flueck
    • 4
  • Barry Kim Humphreys
    • 1
  1. 1.Integrative Spinal Research, Department of Chiropractic MedicineUniversity Hospital BalgristZurichSwitzerland
  2. 2.Biomedical Optics Research Laboratory (BORL), Department of NeonatologyUniversity Hospital Zurich, University of ZurichZurichSwitzerland
  3. 3.Scholkmann Data Analysis ServicesZurichSwitzerland
  4. 4.Laboratory for Muscle Plasticity, Department of OrthopedicsUniversity of Zurich, Balgrist CampusZurichSwitzerland

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