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The History of Lung Transplantation

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Lung Transplantation

Abstract

This chapter presents a historical milestone of lung transplantation from the early experimental studies and clinical attempts to the advances of the Toronto Group and Stanford Group to the most recent developments.

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References

  1. Demikhov VP. Experimental transplantation of vital organs. New York: Consultants Bureau; 1962.

    Google Scholar 

  2. Vigneswaran W, Garrity E, Odell J. Lung transplantation: principles and practice. General topics. History of lung transplantation. Boca Raton: CRC Press; 2015.

    Google Scholar 

  3. Carrel A, Guthrie CC. Anastomosis of blood vessels by the patching method and transplantation of kidney (classical article reprinted from JAMA 1906;47:1648-51). Yale J Biol Med. 2001;74:243–7.

    PubMed  PubMed Central  CAS  Google Scholar 

  4. Carrel A. The surgery of blood vessels, etc. Bull John Hopkins Hosp. 1907;18:18–28.

    Google Scholar 

  5. Murray JE, Merril JP, Harrison JH. Kidney transplantation between seven pairs of identical twins. Ann Surg. 1958;148:343–57.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Metras H. Note preliminare sur la greffe totale du pumon chez le chien. Proc Acad Sci (Paris). 1950;231:1176–8.

    Google Scholar 

  7. Staudacher V, Bellinazzo P, Pulin A. Primi rilievi su tentativi di reimpianti autoplastici e di trapianti omoplastici dei lobi pulmonari. Chirurgia (Milano). 1959;5:233–27.

    Google Scholar 

  8. Juvenelle AA, Citret C, Wiles CE, Stewart JD. Pneumonectomy with replantation of the lung in the dog for physiologic study. J Thorac Surg. 1951;21:111–5.

    PubMed  CAS  Google Scholar 

  9. Neptune WB, Weller R, Bailey CP. Experimental lung transplantation. J Thorac Surg. 1953;26:275–89.

    PubMed  CAS  Google Scholar 

  10. Hardin CA, Kittle CE. Experiences with transplantation of the lung. Science. 1954;119:97–8.

    Article  CAS  PubMed  Google Scholar 

  11. Shumway SJ, Shumway NE. Thoracic transplantation. Part I. Historical background. Blackwell Science: Cambridge; 1995.

    Google Scholar 

  12. Blumenstock DA, Collin JA, Thomas ED, Ferrebee JW. Homotransplants of the lung in dogs. Surgery. 1962;51:541–5.

    Google Scholar 

  13. Hardy JD, Eraslan S, Dalton ML Jr, Alican F, Turner MD. Re-implantation and homotransplantations of the lung: laboratory studies and clinical potential. Ann Surg. 1963;157:707–18.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Hardy JD, Webb WR, Dalton ML, Walker GR. Lung homotransplantations in man. JAMA. 1963;186:1065–74.

    Article  CAS  PubMed  Google Scholar 

  15. Derom F, Barbier F, Ringoir S, Versieck J, Rolly G, Berzsenyi G, Vermeire P, Vrints L. Ten month survival after lung homotransplantations in man. J Thorac Cardiovasc Surg. 1971;61:835–46.

    CAS  PubMed  Google Scholar 

  16. Veith FJ. Lung transplantation. Ann Thorac Surg. 1970;9:580–3.

    Article  CAS  PubMed  Google Scholar 

  17. Nakae S, Webb WR, Theodorides T, Sugg WL. Respiratory function following cardiopulmonary denervation in dog, cat, and monkey. Surg Gynecol Obstet. 1967;125:1285–92.

    PubMed  CAS  Google Scholar 

  18. Yeh TJ, Ellison LT, Ellison RG. Functional evaluation of the autotransplanted lung in the dog. Am Rev Resp Dis. 1962;86:791–7.

    PubMed  CAS  Google Scholar 

  19. Linberg EJ, Demetriades A, Armstrong BW, Konsuwan N. Lung reimplantation in the dog. JAMA. 1961;178:486–7.

    Article  CAS  PubMed  Google Scholar 

  20. Blumenstock DA, Kahn DR. Replantation and transplantation of the canine lung. J Surg Res. 1961;1:40–7.

    Article  Google Scholar 

  21. Veith FJ, Richards K. Improved technic for canine lung transplantation. Ann Surg. 1970;171:553–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Nelems JMB, Rebuck AS, Cooper JD, Goldberg M, Halloran PF, Vellend H. Human lung transplantation. Chest. 1980;78:569–73.

    Article  CAS  PubMed  Google Scholar 

  23. Lima O, Cooper JD, Peters WJ, Ayabe H, Townsend E, Luk SC, Goldberg M. Effects of methylprednisolone and azathioprine on bronchial healing following lung autotransplantation. J Thorac Cardiovasc Surg. 1981;82:211–5.

    PubMed  CAS  Google Scholar 

  24. Goldberg M, Lima O, Morgan E, Ayabe HA, Luk S, Ferdman A, Peters WJ, Cooper JD. A comparison between cyclosporin A and methylprednisolone plus azathioprine on bronchial healing following canine lung autotransplantation. J Thorac Cardiovasc Surg. 1983;85:821–6.

    PubMed  CAS  Google Scholar 

  25. Stone RM, Ginsberg RJ, Colapinto RF, Pearson FG. Bronchial artery regeneration after radical hilar stripping. Surg Forum. 1966;17:109–10.

    PubMed  CAS  Google Scholar 

  26. Mills NL, Boyd AD, Gheranpong C, Spencer FC. The significance of bronchial circulation in lung transplantation. J Thorac Cardiovasc Surg. 1970;60:866–74.

    PubMed  CAS  Google Scholar 

  27. Pearson FG, Golberg M, Stone RM, Colapinto RF. Bronchial arterial circulation restored after reimplantation of canine lung. Can J Surg. 1970;13:243–50.

    PubMed  CAS  Google Scholar 

  28. Rabinovich JJ. Re-establishment of bronchial arteries after experimental lung lobe autotransplantation. J Thorac Cardiovasc Surg. 1972;64:119–26.

    PubMed  CAS  Google Scholar 

  29. Siegelman SS, Hagstrom JWC, Koerner SR, Veith FJ. Restoration of bronchial artery circulation after canine lung allotransplantation. J Thorac Cardiovasc Surg. 1977;73:792–5.

    PubMed  CAS  Google Scholar 

  30. Lima O, Goldberg M, Peters WJ, Ayabe H, Townsend E, Cooper JD. Bronchial omentopexy in canine lung transplantation. J Thorac Cardiovasc Surg. 1982;83:418–21.

    PubMed  CAS  Google Scholar 

  31. Reitz BA, Wallwork JL, Hunt SA, Pennock JL, Billingham ME, Oyer PE, Stinson EB, Shumway NE. Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease. N Engl J Med. 1982;306:557–64.

    Article  CAS  PubMed  Google Scholar 

  32. Toronto Lung Transplant Group. Sequential bilateral lung transplantation for Paraquat poisoning. J Thorac Cardiovasc Surg. 1985;89:734–42.

    Google Scholar 

  33. Toronto Lung Transplant Group. Unilateral lung transplantation for pulmonary fibrosis. N Engl J Med. 1986;314:1140–5.

    Article  Google Scholar 

  34. Dark JH, Patterson GA, Al-Jilaihawi AN, Hsu H, Egan TM, Cooper JD. Experimental en bloc double-lung transplantation. Ann Thorac Surg. 1986;42(4):394–8.

    Article  CAS  PubMed  Google Scholar 

  35. Cooper JD, Pearson FG, Patterson GA, Todd TR, Ginsberg RJ, Goldberg M, DeMajo WA. Technique of successful lung transplantation in humans. J Thorac Cardiovasc Surg. 1987;93(2):173–81.

    PubMed  CAS  Google Scholar 

  36. Calhoon JH, Grover FL, Gibbons WJ, Bryan CL, Levine SM, Bailey SR, Nichols L, Lum C, Trinkle JK. Single lung transplantation. Alternative indications and technique. J Thorac Cardiovasc Surg. 1991;101(5):816–24.

    PubMed  CAS  Google Scholar 

  37. Garfein ES, Ginsberg ME, Gorenstein L, McGregor CC, Schulman LL. Superiority of end-to-end versus telescoped bronchial anastomosis in single lung transplantation for pulmonary emphysema. J Thorac Cardiovasc Surg. 2001;121(1):149–54.

    Article  CAS  PubMed  Google Scholar 

  38. Schröder C, Scholl F, Daon E, Goodwin A, Frist WH, Roberts JR, Christian KG, Ninan M, Milstone AP, Loyd JE, Merrill WH, Pierson RN III. A modified bronchial anastomosis technique for lung transplantation. Ann Thorac Surg. 2003;75(6):1697–704.

    Article  PubMed  Google Scholar 

  39. Egan TM, Kaiser LR, Cooper JD. Lung transplantation. Curr Probl Surg. 1989;26:673–751.

    Article  CAS  PubMed  Google Scholar 

  40. Goldsmith MF. Mother to child: first living donor lung transplant. JAMA. 1990;264:2724.

    Article  CAS  PubMed  Google Scholar 

  41. American Thoracic Society, Medical Section of the American Lung Association. Lung transplantation. Report of the ATS workshop on lung transplantation. American Thoracic Society, Medical Section of the American Lung Association. Am Rev Respir Dis. 1993;147:772–6.

    Google Scholar 

  42. Egan TM, Murray S, Bustami RT, Shearon TH, McCullough KP, Edwards LB, Coke MA, Garrity ER, Sweet SC, Heiney DA, Grover FL. Development of the new lung allocation system in the United States. Am J Transplant. 2006;6:1212–27.

    Article  CAS  PubMed  Google Scholar 

  43. Health Resources and Services Administration (HRSA), Department of Health and Human Services (HHS). Organ procurement and transplantation network. Final Rule. Fed Regist. 2013;78:40033–42.

    Google Scholar 

  44. Schreinemakers HHJ, De Leyn PRJ, Marcus M, Wouters P, Moerman F, Flameng W, Lerut A, Cooper J. Role of bronchial arteries in lung function. Ann Thorac Surg. 1992;54:395–7.

    Article  Google Scholar 

  45. Daly RC, McGregor CG. Routine immediate direct bronchial artery revascularization for single-lung transplantation. Ann Thorac Surg. 1994;57:1446–52.

    Article  CAS  PubMed  Google Scholar 

  46. Schreinemakers HH, Weder W, Miyoshi S, Harper BD, Shimokawa S, Egan TM, McKnight R, Cooper JD. Direct revascularization of bronchial arteries for lung transplantation: an anatomical study. Ann Thorac Surg. 1990;49:44–53.

    Article  CAS  PubMed  Google Scholar 

  47. Couraud L, Baudet E, Martigne C, Roques X, Velly JF, Laborde N, Dubrez J, Clerc F, Dromer C, Vallieres E. Bronchial revascularization in double-lung transplantation: a series of 8 patients. Bordeaux Lung and Heart-Lung Transplant Group. Ann Thorac Surg. 1992;53:88–94.

    Article  CAS  PubMed  Google Scholar 

  48. Pettersson G, Nørgaard MA, Arendrup H, Brandenhof P, Helvind M, Joyce F, Stentoft P, Olesen PS, Thiis JJ, Efsen F, Mortensen SA, Svendsen UG. Direct bronchial artery revascularization and en bloc double lung transplantation—surgical techniques and early outcome. J Heart Lung Transplant. 1997;16:320–33.

    PubMed  CAS  Google Scholar 

  49. Daly RC, Tadjkarimi S, Khaghani A, Banner NR, Yacoub MH. Successful double-lung transplantation with direct bronchial artery revascularization. Ann Thorac Surg. 1993;56:885–92.

    Article  CAS  PubMed  Google Scholar 

  50. Nørgaard MA, Olsen PS, Svendsen UG, Pettersson G. Revascularization of the bronchial arteries in lung transplantation: an overview. Ann Thorac Surg. 1996;62:1215–21.

    Article  PubMed  Google Scholar 

  51. Nørgaard MA, Efsen F, Arendrup H, Olsen PS, Svendsen UG, Pettersson G. Surgical and arteriographic results of bronchial artery revascularization in lung and heart lung transplantation. J Heart Lung Transplant. 1997;16:302–12.

    PubMed  Google Scholar 

  52. Pettersson GB, Yun JJ, Nørgaard MA. Bronchial artery revascularization in lung transplantation: techniques, experience, and outcomes. Curr Opin Organ Transplant. 2010;15:572–7.

    Article  PubMed  Google Scholar 

  53. Reeb J, Cypel M. Ex vivo lung perfusion. Clin Transpl. 2016;30(3):183–94.

    Article  Google Scholar 

  54. Carrel A, Lindbergh CA. The culture of whole organs. Science. 1935;81:621–3.

    Article  CAS  PubMed  Google Scholar 

  55. Jirsch DW, Fisk RL, Couves CM. Ex vivo evaluation of stored lungs. Ann Thorac Surg. 1970;10(2):163–8.

    Article  CAS  PubMed  Google Scholar 

  56. Steen S, Sjoberg T, Pierre L, Liao Q, Eriksson L, Algotsson L. Transplantation of lungs from non-heart beating donor. Lancet. 2001;357:825–9.

    Article  CAS  PubMed  Google Scholar 

  57. Steen S, Liao Q, Wierup PN, Bolys R, Pierre L, Sjöberg T. Transplantation of lungs from non-heart-beating donors after functional assessment ex vivo. Ann Thorac Surg. 2003;76(1):244–52.

    Article  PubMed  Google Scholar 

  58. Steen S, Ingemansson R, Eriksson L, Pierre L, Algotsson L, Wierup P, Liao Q, Eyjolfsson A, Gustafsson R, Sjöberg T. First human transplantation of a nonacceptable donor lung after reconditioning ex vivo. Ann Thorac Surg. 2007;83(6):2191–4.

    Article  PubMed  Google Scholar 

  59. Cypel M, Yeung JC, Hirayama S, Rubacha M, Fischer S, Anraku M, Sato M, Harwood S, Pierre A, Waddell TK, de Perrot M, Liu M, Keshavjee S. Technique for prolonged normothermic ex vivo lung perfusion. J Heart Lung Transplant. 2008;27(12):1319–25.

    Article  PubMed  Google Scholar 

  60. Love RB, Stringham JC, Chomiak PN, Warner T, Pellett JR, Mentzer RM. Successful lung transplantation using a non-heart-beating donor [abstract]. J Heart Lung Transplant. 1995;14:S88.

    Google Scholar 

  61. Snell GI, Levvey BJ, Oto T, McEgan R, Pilcher D, Davies A, Marasco S, Rosenfeldt F. Early lung transplantation success utilizing controlled donation after cardiac death donors. Am J Transplant. 2008;8(6):1282–9.

    Article  CAS  PubMed  Google Scholar 

  62. Reeb J, Keshavjee S, Cypel M. Expanding the lung donor pool: advancements and emerging pathways. Curr Opin Organ Transplant. 2015;20(5):498–505.

    Article  PubMed  Google Scholar 

  63. Cypel M, Levvey B, Van Raemdonck D, Erasmus M, Dark J, Love R, Mason D, Glanville AR, Chambers D, Edwards LB, Stehlik J, Hertz M, Whitson BA, Yusen RD, Puri V, Hopkins P, Snell G, Keshavjee S, International Society for Heart and Lung Transplantation. International Society for Heart and Lung Transplantation donation after Circulatory Death Registry Report. J Heart Lung Transplant. 2015;34(10):1278–82.

    Article  PubMed  Google Scholar 

  64. Egan TM. Lung transplant from an uncontrolled donation after circulatory determination of death donor: moving to other countries. Am J Transplant. 2016;16(4):1051–2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  65. Egan TM, Requard JJ. Uncontrolled donation after circulatory determination of death donors (uDCDDs) as a source of lungs for transplant. Am J Transplant. 2015;15(8):2031–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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D’Armini, A.M., Grazioli, V., Viganò, M. (2018). The History of Lung Transplantation. In: Raghu, G., Carbone, R. (eds) Lung Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-91184-7_1

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  • DOI: https://doi.org/10.1007/978-3-319-91184-7_1

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