Renal Function Monitoring in a Critically Sick Patient
Causes of Acute Kidney Injury (AKI) are multifactorial; risk and severity are increased by preexisting renal insufficiency and by co-morbidities. Predicting likelihood of AKI and careful monitoring are crucial to modify management and change clinical course. Sepsis, hypovolaemia and nephrotoxic agents are important factors in AKI and are modifiable. Some renal failure is caused by nephro-urological disease for which there may be specific therapy. Failure to recognize AKI early results in significant kidney damage. Acute kidney injury (AKI) and fluid overload are independently associated with short- and long-term morbidity and mortality. Focus on preservation of renal function is important.
KeywordsAKI, acute kidney injury Acute kidney insufficiency Blood pressure Hypovolaemia Nephrotoxicity Oliguria Creatinine GFR
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