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Proximal Small Intestine: Inflammatory Patterns

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Endoscopic Biopsy Interpretation

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Abstract

This chapter details the inflammatory reaction patterns and the tumour-forming processes found in mucosal biopsy specimens and mucosal resection specimens of the small intestine. In terms of inflammatory reactions, most attention is given to the finding of intraepithelial lymphocytosis with associated lamina propria inflammation. The major diagnostic consideration is coeliac disease; however, the other causes of this reaction pattern are fully discussed. Less common inflammatory processes and their causes are also presented following the schema developed in Chap. 1. Finally, infective conditions affecting the small intestine, but often elsewhere in the gastrointestinal tract, are fully covered in this chapter.

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References

  1. Caselli M, Gaudio M, Chiamenti CM, Trevisani L, Sartori S, Saragoni L, Boldrini P, Dentale A, Ruina M, Alvisi V. Histologic findings and Helicobacter pylori in duodenal biopsies. J Clin Gastroenterol. 1998;26(1):74–80.

    Article  CAS  PubMed  Google Scholar 

  2. Wyatt JI, Rathbone BJ, Sobala GM, Shallcross T, Heatley RV, Axon AT, Dixon MF. Gastric epithelium in the duodenum: its association with Helicobacter pylori and inflammation. J Clin Pathol. 1990;43(12):981–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Khulusi S, Badve S, Patel P, Lloyd R, Marrero JM, Finlayson C, Mendall MA, Northfield TC. Pathogenesis of gastric metaplasia of the human duodenum: role of Helicobacter pylori, gastric acid, and ulceration. Gastroenterology. 1996;110(2):452–8.

    Article  CAS  PubMed  Google Scholar 

  4. Moran CJ, Kolman OK, Russell GJ, Brown IS, Mino-Kenudson M. Neutrophilic infiltration in gluten-sensitive enteropathy is neither uncommon nor insignificant: assessment of duodenal biopsies from 267 pediatric and adult patients. Am J Surg Pathol. 2012;36(9):1339–45.

    Article  PubMed  Google Scholar 

  5. De Petris G, López JI. Histopathology of diaphragm disease of the small intestine. Am J Clin Pathol. 2008;130:518–25.

    Article  PubMed  Google Scholar 

  6. Isaacs PE, Sladen GE, Filipe I. Mefenamic acid Enteropathy. J Clin Pathol. 1987;40(10):1221–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Brown IS, Miller GC, Bettington ML, Rosty C. Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn’s disease-related ileitis. Virchows Arch. 2017;470:597.

    Article  PubMed  Google Scholar 

  8. Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut. 2006;55(6):749–53.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Paerregaard A. What Does the IBD Patient Hide in the Upper Gastrointestinal Tract? Inflamm Bowel Dis. 2009;15(7):1101–4.

    Article  PubMed  Google Scholar 

  10. Biagi F, Luinetti O, Campanella J, et al. Intraepithelial lymphocytes in the villous tip: do they indicate potential celiac disease? J Clin Pathol. 2004;57:835.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Verress B, Franzen L, Bodin L, Borch K. Duodenal intraepithelial lymphocyte-count revisited. Scand J Gastroenterol. 2004;4:138.

    Article  Google Scholar 

  12. Hayat M, Cairns A, Dixon MF, O’Mahony S. Quantitation of intraepithelial lymphocytes in human duodenum: what is normal? J Clin Pathol. 2002;55:393.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Brown I, Mino-Kenudson M, Deshpande V, Lauwers GY. Intraepithelial lymphocytosis in architecturally preserved proximal small intestinal mucosa - an increasing diagnostic problem with a wide differential diagnosis. Arch Pathol Lab Med. 2006;130(7):1020–5.

    PubMed  Google Scholar 

  14. Kakar S, Mehra V, et al. Significance of intraepithelial lymphocytosis in small bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol. 2003;98(9):2027–33.

    Article  PubMed  Google Scholar 

  15. Mahadeva S, Wyatt JI, et al. Is a raised intraepithelial lymphocyte count with normal duodenal villous architecture clinically relevant? J Clin Pathol. 2002;55:424–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Goldstein NS, Underhill J. Morphologic features suggestive of gluten sensitivity in architecturally normal duodenal biopsy specimens. Am J Clin Pathol. 2001;116:63–71.

    Article  CAS  PubMed  Google Scholar 

  17. Robert ME. Gluten sensitive enteropathy and other causes of small intestinal lymphocytosis. Semin Diagn Pathol. 2005;22(4):284–94.

    Article  PubMed  Google Scholar 

  18. Chang F, Mahadeva U, Deere H. Pathological and clinical significance of increased intraepithelial lymphocytes (IELs) in small bowel mucosa. APMIS. 2005;113:385.

    Article  PubMed  Google Scholar 

  19. Rosinach M, et al. Lymphocytic duodenosis: aetiology and long-term response to specific treatment. Dig Liver Dis. 2012;44(8):643–8.

    Article  PubMed  Google Scholar 

  20. Aziz I, Evans KE, Hopper AD, et al. A prospective study into the aetiology of lymphocytic duodenosis. Aliment Pharmacol Ther. 2010;32:1392–7.

    Article  CAS  PubMed  Google Scholar 

  21. Shmidt E, Smyrk TC, Faubion WA, Oxentenko AS. Duodenal intraepithelial lymphocytosis with normal villous architecture in pediatric patients: Mayo Clinic experience, 2000-2009. J Pediatr Gastroenterol Nutr. 2013;56(1):51–5.

    Article  PubMed  Google Scholar 

  22. Mino-Kenudson M, Brown I, Lauwers GY. Histopathological diagnosis of gluten-sensitive enteropathy. Curr Diagn Pathol. 2005;11(4):274–83.

    Article  Google Scholar 

  23. Brown I, Smith J, Rosty C. Gastrointestinal pathology in celiac disease: a case series of 150 consecutive newly diagnosed patients. Am J Clin Pathol. 2012;138(1):42–9.

    Article  PubMed  Google Scholar 

  24. Antonioli D. Celiac disease: a progress report. Mod Pathol. 2003;16(4):342–6.

    Article  PubMed  Google Scholar 

  25. Owens SR, Greenson JK. The pathology of malabsorption: current concepts. Histopathology. 2007;50(1):64–82.

    Article  CAS  PubMed  Google Scholar 

  26. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of celiac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol. 1999;11:1185.

    Article  CAS  PubMed  Google Scholar 

  27. Corazza GR, Villanacci V. Celiac disease. J Clin Pathol. 2005;58:573.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Weir DC, Glickman JN, Roiff T, et al. Variability of histopathological changes in childhood celiac disease. Am J Gastroenterol. 2010;105(1):207–12.

    Article  PubMed  Google Scholar 

  29. Ravelli A, Bolognini S, Gambarotti M, Villanacci V. Variability of histologic lesions in relation to biopsy site in gluten-sensitive enteropathy. Am J Gastroenterol. 2005;100:177.

    Article  PubMed  Google Scholar 

  30. Daum S, Cellier C, Mulder CJ. Refractory celiac disease. Best Pract Res Clin Gastroenterol. 2005;19:413.

    Article  PubMed  Google Scholar 

  31. Robert ME, Ament ME, Weinstein WM. The histologic spectrum and clinical outcome of refractory and unclassified sprue. Am J Surg Pathol. 2000;24:676.

    Article  CAS  PubMed  Google Scholar 

  32. Di Sabatino A, Miceli E, Dhaliwal W, et al. Distribution, proliferation, and function of Paneth cells in uncomplicated and complicated adult celiac disease. Am J Clin Pathol. 2008;130:34.

    Article  CAS  PubMed  Google Scholar 

  33. Ho-Yen C, Chang F, van der Walt J, Mitchell T, Ciclitira P. Recent advances in refractory celiac disease: a review. Histopathology. 2009;54:783.

    Article  CAS  PubMed  Google Scholar 

  34. Al-Toma A, Verbeek WH, Mulder CJ. Update on the management of refractory celiac disease. J Gastrointestin Liver Dis. 2007;16:57.

    PubMed  Google Scholar 

  35. Patey-Mariaud De Serre N, Cellier C, et al. Distinction between celiac disease and refractory sprue: a simple immunohistochemical method. Histopathology. 2000;37:70.

    Article  CAS  PubMed  Google Scholar 

  36. Rubio-Tapia A, Murray JA. Classification and management of refractory celiac disease. Gut. 2010;59(4):547–57.

    Article  PubMed  Google Scholar 

  37. Choi EY, McKenna BJ. Olmesartan-associated enteropathy: a review of clinical and histologic findings. Arch Pathol Lab Med. 2015;139(10):1242–7.

    Article  CAS  PubMed  Google Scholar 

  38. Akram S, Murray JA, Pardi DS, et al. Adult autoimmune enteropathy: Mayo Clinic Rochester experience. Clin Gastroenterol Hepatol. 2007;5:1282.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Montalto M, D’Onofrio F, Santoro L, et al. Autoimmune enteropathy in children and adults. Scand J Gastroenterol. 2009;44:1029.

    Article  CAS  PubMed  Google Scholar 

  40. Patey-Mariaud de Serre N, Canioni D, Ganousse S, et al. Digestive histopathological presentation of IPEX syndrome. Mod Pathol. 2009;22:95.

    Article  CAS  PubMed  Google Scholar 

  41. Masia R, Peyton S, Lauwers GY, Brown I. Gastrointestinal biopsy findings of autoimmune enteropathy: a review of 25 cases. Am J Surg Pathol. 2014;38(10):1319–29.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Kesuaai I, Kuitonen P, Savilahti E, Sippenen P. Mast cells and eosinophils in the jejunal mucosa of patients with intestinal cows’ milk allergy and celiac disease of childhood. J Pediatr Gastroenterol Nutr. 1984;3:368.

    Article  Google Scholar 

  43. Kokkonen J, Holm K, Karttunen TJ, Mäki M. Children with untreated food allergy express a relative increment in the density of duodenal gammadelta+ T cells. Scand J Gastroenterol. 2000;35:1137.

    Article  CAS  PubMed  Google Scholar 

  44. Ament ME, Rubin CE. Soy protein—another cause of the flat intestinal lesion. Gastroenterology. 1972;62:227.

    CAS  PubMed  Google Scholar 

  45. Vitoria JC, Camerero C, Sojo A, Ruiz A, Roderiguez-Soriano J. Enteropathy related to fish, rice, and chicken. Arch Dis Child. 1982;57:44.

    CAS  PubMed  PubMed Central  Google Scholar 

  46. Batheja MJ, Leighton J, Azueta A, Heigh R. The Face of Tropical Sprue in 2010. Case Rep Gastroenterol. 2010;4(2):168–72.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Walker MM. What is tropical sprue? J Gastroenterol Hepatol. 2003;18:887.

    Article  PubMed  Google Scholar 

  48. Haghighi P, Wolf PL. Tropical sprue and subclinical enteropathy: a vision for the nineties. Crit Rev Clin Lab Sci. 1997;34:313.

    Article  CAS  PubMed  Google Scholar 

  49. Nath SK. Tropical sprue. Curr Gastroenterol Rep. 2005;7(5):343–9.

    Article  PubMed  Google Scholar 

  50. Swanson VL, Thomassen RW. Pathology of the jejunal mucosa in tropical sprue. Am J Pathol. 1965;46:511–51.

    CAS  PubMed  PubMed Central  Google Scholar 

  51. Wheby MS, Swanson VL, Bayless TM. Comparison of ileal and jejunal biopsies in tropical sprue. Am J Clin Nutr. 1971;24:117–23.

    Article  CAS  PubMed  Google Scholar 

  52. Brown IS, Bettington A, Bettington M, Rosty C. Tropical Sprue – revisiting an under recognised condition. Am J Surg Pathol. 2014;38(5):666–72.

    Article  PubMed  Google Scholar 

  53. Rana SV, Bhardwaj SB. Small intestinal bacterial overgrowth. Scand J Gastroenterol. 2008;43:1030–7.

    Article  CAS  PubMed  Google Scholar 

  54. Lappinga PJ, Abraham SC, Murray JA, Vetter EA, Patel R, Wu TT. Small intestinal bacterial overgrowth: histopathologic features and clinical correlates in an underrecognized entity. Arch Pathol Lab Med. 2010;134:264–70.

    PubMed  Google Scholar 

  55. Haboubi NY, Lee GS, Montgomery RD. Duodenal mucosal morphometry of elderly patients with small intestinal bacterial overgrowth: response to antibiotic treatment. Age Ageing. 1991;20:29.

    Article  CAS  PubMed  Google Scholar 

  56. Riordan SM, McIver CJ, Wakefield D, et al. Small intestinal mucosal immunity and morphometry in luminal overgrowth of indigenous gut flora. Am J Gastroenterol. 2001;96:494.

    Article  CAS  PubMed  Google Scholar 

  57. Castigli E, Wilson SA, Garibyan L, et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet. 2005;37:829–34.

    Article  CAS  PubMed  Google Scholar 

  58. Malamut G, Verkarre V, Suarez F, Viallard JF, Lascaux AS, Cosnes J, Bouhnik Y, Lambotte O, Béchade D, Ziol M, Lavergne A, Hermine O, Cerf-Bensussan N, Cellier C. The enteropathy associated with common variable immunodeficiency: the delineated frontiers with celiac disease. Am J Gastroenterol. 2010;105(10):2262–75.

    Article  CAS  PubMed  Google Scholar 

  59. Daniels JA, Lederman HM, Maitra A, Montgomery EA. Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review. Am J Surg Pathol. 2007;31(12):1800–12.

    Article  PubMed  Google Scholar 

  60. Washington K, Stenzel TT, Buckley RH, Gottfried MR. Gastrointestinal pathology in patients with common variable immunodeficiency and X-linked agammaglobulinemia. Am J Surg Pathol. 1996;20(10):1240–52.

    Article  CAS  PubMed  Google Scholar 

  61. Joo M, Shim SH, Chang SH, Kim H, Chi JG, Kim NH. Nodular lymphoid hyperplasia and histologic changes mimicking celiac disease, collagenous sprue, and lymphocytic colitis in a patient with selective IgA deficiency. Pathol Res Pract. 2009;205(12):876–80.

    Article  PubMed  Google Scholar 

  62. Maguire AA, Greenson JK, Lauwers GY, et al. Collagenous sprue: a clinicopathologic study of 12 cases. Am J Surg Pathol. 2009;33:1440.

    Article  PubMed  Google Scholar 

  63. Freeman HJ. Update on collagenous sprue. World J Gastroenterol. 2010;16(3):296–8.

    Article  PubMed  PubMed Central  Google Scholar 

  64. DeBrosse CW, Case JW, Putnam PE, et al. Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatr Dev Pathol. 2006;9(3):210–8.

    Article  PubMed  Google Scholar 

  65. Lucendo AJ, Arias A. Eosinophilic gastroenteritis: an update. Expert Rev Gastroenterol Hepatol. 2012;6(5):591–601.

    Article  CAS  PubMed  Google Scholar 

  66. Washington K, Jagasia M. Pathology of graft-versus-host disease in the gastrointestinal tract. Hum Pathol. 2009;40(7):909–17.

    Article  PubMed  Google Scholar 

  67. Snover DC. Graft-versus-host disease of the gastrointestinal tract. Am J Surg Pathol. 1990;14(Suppl 1):101–8.

    PubMed  Google Scholar 

  68. Ogawa F, Mino-Kenudson M, Shimizu M, Ligato S, Lauwers GY. Gastroduodenitis associated with yttrium 90-microsphere selective internal radiation: an iatrogenic complication in need of recognition. Arch Pathol Lab Med. 2008;132(11):1734–8.

    PubMed  Google Scholar 

  69. Conte D, Velio P, Brunelli L, et al. Stainable iron in gastric and duodenal mucosa of primary hemochromatosis patients and alcoholics. Am J Gastroenterol. 1987;82:237–40.

    CAS  PubMed  Google Scholar 

  70. Abraham SC, Yardley JH, Wu TT. Erosive injury to the upper gastrointestinal tract in patients receiving iron medication. Am J Surg Pathol. 1999;23:1241–7.

    Article  CAS  PubMed  Google Scholar 

  71. Kaye P, Abdulla K, Wood J, James P, Foley S, Ragunath K, Atherton J. Iron-induced mucosal pathology of the upper gastrointestinal tract: a common finding in patients on oral iron therapy. Histopathology. 2008;53(3):311–7.

    Article  CAS  PubMed  Google Scholar 

  72. West B. Pseudomelanosis duodeni. J Clin Gastroenterol. 1988;10(2):127–9.

    Article  CAS  PubMed  Google Scholar 

  73. Rex DK, Jersild RA Jr. Further characterization of the pigment in pseudomelanosis duodeni in three patients. Gastroenterology. 1988;95(1):177–82.

    Article  CAS  PubMed  Google Scholar 

  74. Foster CS. The brown bowel syndrome: a possible smooth muscle mitochondrial myopathy. Histopathology. 1979;3:1.

    Article  CAS  PubMed  Google Scholar 

  75. Horn T, Svendsen LB, Nielsen R. Brown-bowel syndrome. Review of the literature and presentation of cases. Scand J Gastroenterol. 1990;25:66.

    Article  CAS  PubMed  Google Scholar 

  76. Brandt LJ, Davidoff A, Bernstein LH, et al. Small-intestine involvement in Waldenstrom’s macroglobulinemia. Case report and review of the literature. Dig Dis Sci. 1981;26:174.

    Article  CAS  PubMed  Google Scholar 

  77. Gad A, Willén R, Carlén B, Gyland F, Wickander M. Duodenal involvement in Waldenström’s macroglobulinemia. J Clin Gastroenterol. 1995;20(2):​174–6.

    Article  CAS  PubMed  Google Scholar 

  78. Harris M, Burton IE, Scarffe JH. Macroglobulinaemia and intestinal lymphangiectasia: a rare association. J Clin Pathol. 1983;36(1):30–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  79. Sattianayagam PT, Hawkins PN, Gillmore JD. Systemic amyloidosis and the gastrointestinal Tract. Nat Rev Gastroenterol Hepatol. 2009;6:608–17.

    Article  CAS  PubMed  Google Scholar 

  80. Ebert EC, Nagar M. Gastrointestinal manifestations of amyloidosis. Am J Gastroenterol. 2008;103(3):776–87.

    Article  PubMed  Google Scholar 

  81. Hemmer PR, Topazian MD, Gertz MA, Abraham SC. Globular amyloid deposits isolated to the small bowel: a rare association with AL amyloidosis. Am J Surg Pathol. 2007;31:141–5.

    Article  PubMed  Google Scholar 

  82. Gould M, Zarrin-Khameh N, Sellin J. Small Bowel Amyloidosis. Curr Gastroenterol Rep. 2013;350(1-6):15.

    Google Scholar 

  83. Cutz E, Rhoads JM, Drumm B, et al. Micro inclusion disease: an inherited defect of brush border assembly and differentiation. N Engl J Med. 1989;320:646.

    Article  CAS  PubMed  Google Scholar 

  84. Groisman G, Ben-Izhak O, Schwersenz A, et al. The value of polyclonal carcinoembryonic antigen immunostaining in the diagnosis of micro inclusion disease. Hum Pathol. 1993;24:1232.

    Article  CAS  PubMed  Google Scholar 

  85. Groisman GM, Amar M, Livne E. CD10: a valuable tool for the light microscopic diagnosis of microvillous inclusion disease (familial microvillous atrophy). Am J Surg Pathol. 2002;26:902.

    Article  PubMed  Google Scholar 

  86. Al-Daraji WI, Zelger B, Zelger B, Hussein MR. Microvillous inclusion disease: a clinicopathologic study of 17 cases from the UK. Ultrastruct Pathol. 2010;34(6):327–32.

    Article  PubMed  Google Scholar 

  87. Bell SW, Kerner JA Jr, Sibley RK. Microvillous inclusion disease. The importance of electron microscopy for diagnosis. Am J Surg Pathol. 1991;15:1157.

    Article  CAS  PubMed  Google Scholar 

  88. Cutz E, Sherman PM, Davidson GP. Enteropathies associated with protracted diarrhea of infancy: clinicopathological features, cellular and molecular mechanisms. Pediatr Pathol Lab Med. 1997;17:335.

    CAS  PubMed  Google Scholar 

  89. Sivagnanam M, Mueller JL, Lee H, et al. Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 2008;135(2):429–37.

    Article  CAS  PubMed  Google Scholar 

  90. Goulet OJ, Brousse N, Canioni D, et al. Syndrome of intractable diarrhoea with persistent villous atrophy in early childhood: a clinicopathological survey of 47 cases. J Pediatr Gastroenterol Nutr. 1998;26:151.

    Article  CAS  PubMed  Google Scholar 

  91. Ranganathan S, Schmitt LA, Sindhi R. Tufting enteropathy revisited: the utility of MOC31 (EpCAM) immunohistochemistry in diagnosis. Am J Surg Pathol. 2014;38(2):265–72.

    Article  PubMed  Google Scholar 

  92. Schmitt S, Küry S, Giraud M, et al. An update on mutations of the SLC39A4 gene in acrodermatitis enteropathica. Hum Mutat. 2009;30:926.

    Article  CAS  PubMed  Google Scholar 

  93. Kuitunen P, Kosnai I, Savilahti E. Morphometric study of the jejunal mucosa in various childhood enteropathies with special reference to intraepithelial lymphocytes. J Pediatr Gastroenterol Nutr. 1982;1:525.

    Article  CAS  PubMed  Google Scholar 

  94. Bohane TD, Cutz E, Hamilton JR, Gall DG. Acrodermatitis enteropathica, zinc, and the Paneth cell. A case report with family studies. Gastroenterology. 1977;73:587.

    CAS  PubMed  Google Scholar 

  95. Kobayashi Y, Suzuki H, Konno T, et al. Ultrastructural alterations of Paneth cells in infants associated with gastrointestinal symptoms. Tohoku J Exp Med. 1983;139:225.

    Article  CAS  PubMed  Google Scholar 

  96. Oberhuber G, Kastner N, Stolte M. Giardiasis: a histologic analysis of 567 cases. Scand J Gastroenterol. 1997;32:48–51.

    Article  CAS  PubMed  Google Scholar 

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  1. Envoi Pathology, Kelvin Grove, QLD, Australia

    Ian Brown

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  1. Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre and University of Western Australia, Perth, WA, Australia

    M. Priyanthi Kumarasinghe

  2. Envoi Pathology, Kelvin Grove, QLD, Australia

    Ian Brown

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Brown, I. (2019). Proximal Small Intestine: Inflammatory Patterns. In: Kumarasinghe, M., Brown, I. (eds) Endoscopic Biopsy Interpretation. Springer, Cham. https://doi.org/10.1007/978-3-319-79117-3_6

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