Abstract
Tumours and polypoid lesions of the colon are the most commonly encountered biopies in gastrointestinal practice. In this chapter, the entities are presented according to the schema outlined in chapter 1. Particular attention is paid to serrated lesions in the colon which is an area where our understanding of the morphological classification and pathogenesis of the lesions has expanded recently. Special attention is also given to inflammatory bowel disease related dysplastic lesions and to mesenchymal lesions of the colon, many of which almost exclusively occur at this site.
Keywords
- Tumour
- Tumour-like lesions
- Non-neoplastic glandular proliferations
- Glandular tumours with no stromal invasion
- Glandular tumour with stromal invasion
- Metastasis
- Diffuse round cell
- Spindle cell pattern
- Non-invasive round cell tumours
- Vascular lesion
- Adipose tissue
- Biphasic pattern
- Stromal expansion
- Cystic lesion
- Inflammatory lesions
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References
Devereaux CE, Devereaux RG. Heterotopic gastric mucosa of the rectum with a review of the literature. J Clin Gastroenterol. 1994;19(1):41–5.
Bettington M, Walker N, Rosty C, et al. Critical appraisal of the diagnosis of the sessile serrated adenoma. Am J Surg Pathol. 2014;38:158–66.
Rex DK, Ahnen DJ, Baron JA, et al. Serrated lesions of the colorectum: review and recommendations from an expert panel. Am J Gastroenterol. 2012;107:1315–29.
Bettington ML, Walker NI, Rosty C, et al. A clinicopathological and molecular analysis of 200 traditional serrated adenomas. Mod Pathol. 2015; Mar;28(3):414–27.
Rosty C, Bettington M. Serrated colorectal polyps and polyposis. Diagn Histopathol. 2014;20:30–7.
Brown I, et al. Adverse histological features in malignant colorectal polyps: a contemporary series of 239 cases. J Clin Pathol. 2016;69(4):292–9.
Ueno H, et al. Risk factors for an adverse outcome in early invasive colorectal carcinoma. Gastroenterology. 2004;127:385–94.
Doyle LA, Hornick JL, Fletcher CD. PEComa of the gastrointestinal tract: clinicopathologic study of 35 cases with evaluation of prognostic parameters. Am J Surg Pathol. 2013;37(12):1769–82.
Nakasono M, Hirokawa M, Muguruma N, Okahisa T, Okamura S, Ito S, Miyamoto H, Wada S, Fukuda T, Sano T. Colorectal xanthomas with polypoid lesion: report of 25 cases. APMIS. 2004;112(1):3–10. Review
Miettinen M, Sarlomo-Rikala M, Sobin LH. Mesenchymal tumors of muscularis mucosae of colon and rectum are benign leiomyomas that should be separated from gastrointestinal stromal tumors--a clinicopathologic and immunohistochemical study of eighty-eight cases. Mod Pathol. 2001;14:950–6.
Gibson JA, Hornick JL. Mucosal schwann cell “hamartoma”: clinicopathologic study of 26 neural colorectal polyps distinct from neurofibromas and mucosal neuromas. Am J Surg Pathol. 2009;33(5):781–7.
An S, Jang J, Min K, Kim MS, Park H, Park YS, Kim J, Lee JH, Song HJ, Kim KJ, Yu E, Hong SM. Granular cell tumor of the gastrointestinal tract: histologic and immunohistochemical analysis of 98 cases. Hum Pathol. 2015;46(6):813–9.
Groisman GM, Polak-Charcon S. Fibroblastic polyp of the colon and colonic perineurioma: 2 names for a single entity? Am J Surg Pathol. 2008;32(7):1088–94.
Huber AR, Shikle JF. Benign fibroblastic polyps of the colon. Arch Pathol Lab Med. 2009;133(11):1872–6.
Williams GT, Bussey HJR, Morson BC. Inflammatory cap polyps of the large intestine. Br J Surg. 1985;72(Suppl):133.
Lobert PF, Appelman HD. Inflammatory cloacogenic polyp. A unique inflammatory lesion of the anal transitional zone. Am J Surg Pathol. 1981;5:761–6.
Nakamura S, Kino I, Akagi T. Inflammatory myoglandular polyps of the colon and rectum. A clinicopathological study of 32 pedunculated polyps, distinct from other types of polyps. Am J Surg Pathol. 1992;16:772–9.
Kelly JK. Polypoid prolapsing mucosal folds in diverticular disease. Am J Surg Pathol. 1991;15:871–8.
Alizart MM, Rosty C, Brown IS. Colonic mucosubmucosal elongated polyp: a clinicopathologic study of 13 cases and review of the literature. Am J Surg Pathol. 2011;35(12):1818–22.
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Brown, I., Miller, G.C. (2019). Large Intestine: Neoplastic Patterns and Mimics. In: Kumarasinghe, M., Brown, I. (eds) Endoscopic Biopsy Interpretation. Springer, Cham. https://doi.org/10.1007/978-3-319-79117-3_11
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DOI: https://doi.org/10.1007/978-3-319-79117-3_11
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