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Epidemiology of Bacterial Resistance

  • Patricia A. BradfordEmail author
Chapter
First Online:
Part of the Emerging Infectious Diseases of the 21st Century book series (EIDC)

Abstract

Bacterial pathogens have developed resistance to antibacterial agents through mutation and acquisition of a panoply of resistance determinants. Outbreaks of resistant strains have caused significant morbidity and mortality in the affected patient populations when they occur. A variety of typing methods are used to track and monitor resistance, including newer molecular techniques such as whole genome sequencing. Resistance has traditionally been centered among hospitalized patients; however, resistant pathogens are being isolated in the community setting with increasing frequency. Some resistant strains have developed into epidemic clones that have spread worldwide, but the factors involved in this dissemination remain undefined.

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Notes

Acknowledgment

I thank Charles R. Dean for assistance with information gathering.

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Antimicrobial Development Specialists, LLCNyackUSA

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