Abstract
Hyaluronic acid (HA) is a glycosaminoglycan composed of numerous repetitions of D-glucuronic acid and N-acetyl-D-glucosamine. It is found naturally in many tissues of the human system, including the skin, the synovial fluid of joints, the vitreous humor of eyes, and the cartilage. About 50% of it is found in the skin. In physiological pH, it is a polyanionic polymer and highly loaded, so that it binds extensively to water, being able to retain it up to 1000 times its volume [1] (Fig. 39.1).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Kablik J, Monheit GD, Yu L, Chang G, Gershkovich J. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg. 2009;35(1):302–12.
Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143(2):155–63.
Glogau RG, Knott HM. Fillers: evolution, regression, and the future. Capitulo 2. Em: soft tissue augmentation. Editado por Jean Carruthers e Alastair Carruthers. Elsevier, 2013.
Sundaram H, Cassuto D. Biophysical characteristics of hyaluronic acid soft-tissues fillers and their relevance to aesthetic applications. Plast Reconstr Surg. 2013;132(4Suppl 2):5S–21S.
Pierre S, Liew S, Bernardin A. Basics of dermal filler rheology. Dermatol Surg. 2015;41(Suppl 1):S120–6.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Hans, N., Sakuma, T. (2020). Introduction: What Is Hyaluronic Acid Filler?. In: Costa, A. (eds) Minimally Invasive Aesthetic Procedures . Springer, Cham. https://doi.org/10.1007/978-3-319-78265-2_39
Download citation
DOI: https://doi.org/10.1007/978-3-319-78265-2_39
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-78264-5
Online ISBN: 978-3-319-78265-2
eBook Packages: MedicineMedicine (R0)