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Diagnostic Approach

  • Alen Bišćanin
Chapter
Part of the Clinical Gastroenterology book series (CG)

Abstract

Diabetic autonomic neuropathy and coexisting histomorphological and biomechanical gastrointestinal tract remodeling lead to impaired gut motility and bacterial overgrowth in diabetics. The whole gastrointestinal tract may be affected, and we can expect motility disorder, abnormal secretion, absorption and transportation. Clinical consequences of colon engagement are diarrhea, constipation, and fecal incontinence (and their alternation or combination) as the most frequent symptoms of enteropathy. In general, diagnosis of diabetic autonomic neuropathy-related diarrhea, constipation, or fecal incontinence will be made by exclusion. There are no strict recommendations about diagnostic workout, and the most usual recommendations for the diagnostic approach to diabetic autonomic neuropathy-related gastrointestinal disorders are based on the experience of individual clinical centers. Diagnostic workout always starts with a detailed patient history, physical examination, and pathological findings, which indicate further specific testing.

Keywords

Diabetic autonomic neuropathy Gastrointestinal complications of diabetes mellitus Diabetic diarrhea Constipation Fecal incontinence Small-intestine bacterial overgrowth (SIBO) 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Alen Bišćanin
    • 1
    • 2
  1. 1.Department of Gastroenterology and HepatologySestre milosrdnice University Hospital CenterZagrebCroatia
  2. 2.School of MedicineUniversity of ZagrebZagrebCroatia

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