Abstract
Lung transplant is performed to treat a number of end-stage pulmonary diseases. Because many of the imaging features of post-transplant complications are nonspecific, accurate interpretation of surveillance scans following lung transplantation requires knowledge of modern surgical techniques and predictable post-procedure complications based on the time course after surgery. Computed tomography (CT) is the mainstay of lung transplantation imaging and will be the primary focus of this review.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Christie JD, Edwards LB, Kucheryavaya AY, Benden C, Dipchand AI, Dobbels F, et al. The Registry of the International Society for Heart and Lung Transplantation: 29th adult lung and heart-lung transplant report-2012. J Heart Lung Transplant. 2012;31(10):1073–86. https://doi.org/10.1016/j.healun.2012.08.004.
Schaffer JM, Singh SK, Reitz BA, Zamanian RT, Mallidi HR. Single- vs double-lung transplantation in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis since the implementation of lung allocation based on medical need. JAMA. 2015;313(9):936–48. https://doi.org/10.1001/jama.2015.1175.
Ng YL, Paul N, Patsios D, Walsham A, Chung TB, Keshavjee S, Weisbrod G. Imaging of lung transplantation: review. AJR Am J Roentgenol. 2009;192(3 Suppl):S1–13, quiz S14–9. https://doi.org/10.2214/ajr.07.7061.
Krishnam MS, Suh RD, Tomasian A, Goldin JG, Lai C, Brown K, et al. Postoperative complications of lung transplantation: radiologic findings along a time continuum. Radiographics. 2007;27(4):957–74. https://doi.org/10.1148/rg.274065141.
Madan R, Chansakul T, Goldberg HJ. Imaging in lung transplants: checklist for the radiologist. Indian J Radiol Imaging. 2014;24(4):318–26. https://doi.org/10.4103/0971-3026.143894.
Ward S, Muller NL. Pulmonary complications following lung transplantation. Clin Radiol. 2000;55(5):332–9. https://doi.org/10.1053/crad.2000.0439.
Bittner HB, Dunitz J, Hertz M, Bolman MR 3rd, Park SJ. Hyperacute rejection in single lung transplantation—case report of successful management by means of plasmapheresis and antithymocyte globulin treatment. Transplantation. 2001;71(5):649–51.
Kundu S, Herman SJ, Winton TL. Reperfusion edema after lung transplantation: radiographic manifestations. Radiology. 1998;206(1):75–80. https://doi.org/10.1148/radiology.206.1.9423654.
Ferrer J, Roldan J, Roman A, Bravo C, Monforte V, Pallissa E, et al. Acute and chronic pleural complications in lung transplantation. J Heart Lung Transplant. 2003;22(11):1217–25.
Herridge MS, de Hoyos AL, Chaparro C, Winton TL, Kesten S, Maurer JR. Pleural complications in lung transplant recipients. J Thorac Cardiovasc Surg. 1995;110(1):22–6. https://doi.org/10.1016/s0022-5223(05)80005-4.
Grathwohl KW, Derdak S. Images in clinical medicine. Buffalo chest. N Engl J Med. 2003;349(19):1829. https://doi.org/10.1056/NEJMicm010281.
Erasmus JJ, McAdams HP, Tapson VF, Murray JG, Davis RD. Radiologic issues in lung transplantation for end-stage pulmonary disease. AJR Am J Roentgenol. 1997;169(1):69–78. https://doi.org/10.2214/ajr.169.1.9207503.
King-Biggs MB. Acute pulmonary allograft rejection. Mechanisms, diagnosis, and management. Clin Chest Med. 1997;18(2):301–10.
Semenkovich JW, Glazer HS, Anderson DC, Arcidi JM Jr, Cooper JD, Patterson GA. Bronchial dehiscence in lung transplantation: CT evaluation. Radiology. 1995;194(1):205–8. https://doi.org/10.1148/radiology.194.1.7997554.
Kshettry VR, Kroshus TJ, Hertz MI, Hunter DW, Shumway SJ, Bolman RM 3rd. Early and late airway complications after lung transplantation: incidence and management. Ann Thorac Surg. 1997;63(6):1576–83.
Burns KE, Iacono AT. Pulmonary embolism on postmortem examination: an under-recognized complication in lung-transplant recipients? Transplantation. 2004;77(5):692–8.
Shlobin OA, Dropulic LK, Orens JB, McDyer JF, Conte JV, Yang SY, Girgis R. Mediastinal mass due to Aspergillus fumigatus after lung transplantation: a case report. J Heart Lung Transplant. 2005;24(11):1991–4. https://doi.org/10.1016/j.healun.2005.02.020.
Collins J, Muller NL, Kazerooni EA, Paciocco G. CT findings of pneumonia after lung transplantation. AJR Am J Roentgenol. 2000;175(3):811–8. https://doi.org/10.2214/ajr.175.3.1750811.
Paraskeva M, Bailey M, Levvey BJ, Griffiths AP, Kotsimbos TC, Williams TP, et al. Cytomegalovirus replication within the lung allograft is associated with bronchiolitis obliterans syndrome. Am J Transplant. 2011;11(10):2190–6. https://doi.org/10.1111/j.1600-6143.2011.03663.x.
King BJ, Iyer H, Leidi AA, Carby MR. Gastroesophageal reflux in bronchiolitis obliterans syndrome: a new perspective. J Heart Lung Transplant. 2009;28(9):870–5. https://doi.org/10.1016/j.healun.2009.05.040.
Verleden GM, Raghu G, Meyer KC, Glanville AR, Corris P. A new classification system for chronic lung allograft dysfunction. J Heart Lung Transplant. 2014;33(2):127–33. https://doi.org/10.1016/j.healun.2013.10.022.
Konen E, Weisbrod GL, Pakhale S, Chung T, Paul NS, Hutcheon MA. Fibrosis of the upper lobes: a newly identified late-onset complication after lung transplantation? AJR Am J Roentgenol. 2003;181(6):1539–43. https://doi.org/10.2214/ajr.181.6.1811539.
Ofek E, Sato M, Saito T, Wagnetz U, Roberts HC, Chaparro C, et al. Restrictive allograft syndrome post lung transplantation is characterized by pleuroparenchymal fibroelastosis. Mod Pathol. 2013;26(3):350–6. https://doi.org/10.1038/modpathol.2012.171.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Kadoch, M., Guo, H.H. (2018). Lung Transplantation Imaging. In: Fananapazir, G., Lamba, R. (eds) Transplantation Imaging. Springer, Cham. https://doi.org/10.1007/978-3-319-75266-2_3
Download citation
DOI: https://doi.org/10.1007/978-3-319-75266-2_3
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-75264-8
Online ISBN: 978-3-319-75266-2
eBook Packages: MedicineMedicine (R0)