Skip to main content

Brain Tumor Segmentation Using an Adversarial Network

  • Conference paper
  • First Online:
Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (BrainLes 2017)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 10670))

Included in the following conference series:

Abstract

Recently, the convolutional neural network (CNN) has been successfully applied to the task of brain tumor segmentation. However, the effectiveness of a CNN-based method is limited by the small receptive field, and the segmentation results don’t perform well in the spatial contiguity. Therefore, many attempts have been made to strengthen the spatial contiguity of the network output. In this paper, we proposed an adversarial training approach to train the CNN network. A discriminator network is trained along with a generator network which produces the synthetic segmentation results. The discriminator network is encouraged to discriminate the synthetic labels from the ground truth labels. Adversarial adjustments provided by the discriminator network are fed back to the generator network to help reduce the differences between the synthetic labels and the ground truth labels and reinforce the spatial contiguity with high-order loss terms. The presented method is evaluated on the Brats2017 training dataset. The experiment results demonstrate that the presented method could enhance the spatial contiguity of the segmentation results and improve the segmentation accuracy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Menze, B.H., Jakab, A., Bauer, S., Kalpathy-Cramer, J., Farahani, K., Kirby, J., et al.: The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2015)

    Article  Google Scholar 

  2. Pereira, S., Pinto, A., Alves, V., Silva, C.A.: Brain tumor segmentation using convolutional neural networks in MR images. IEEE Trans. on Med. Imaging 35(5), 1240–1251 (2016)

    Article  Google Scholar 

  3. Zhao, X., Wu, Y., Song, G., Li, Z., Fan, Y., Zhang, Y.: Brain tumor segmentation using a fully convolutional neural network with conditional random fields. In: Crimi, A., Menze, B., Maier, O., Reyes, M., Winzeck, S., Handels, H. (eds.) BrainLes 2016. LNCS, vol. 10154, pp. 77–80. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-55524-9_8

    Google Scholar 

  4. Havaei, M., Davy, A., Wardefarley, D., Biard, A., Courville, A., Bengio, Y., et al.: Brain tumor segmentation with deep neural networks. Med. Image Anal. 35, 18–31 (2017)

    Article  Google Scholar 

  5. Li, Z., Wang, Y., Yu, J., Shi, Z., Guo, Y., Chen, L., et al.: Low grade glioma segmentation based on CNN with fully connected CRF. J. Healthc. Eng. 2017 (2017). https://doi.org/10.1155/2017/9283480. Article No. 9283480

  6. Kamnitsas, K., Ledig, C., Newcombe, V.F., Simpson, J.P., Kane, A.D., Menon, D.K., et al.: Efficient multi-scale 3D CNN with fully connected crf for accurate brain lesion segmentation. Med. Image Anal. 36, 61–78 (2017)

    Article  Google Scholar 

  7. Luc, P., Couprie, C., Chintala, S., Verbeek, J.: Semantic segmentation using adversarial networks. arXiv:1611.08408 (2016)

  8. Goodfellow, I.J., Pouget-Abadie, J., Mirza, M., Xu, B., Warde-Farley, D., Ozair, S., et al.: Generative adversarial networks. In: NIPS, pp. 2672–2680 (2014)

    Google Scholar 

  9. Radford, A., Metz, L., Chintala, S.: Unsupervised representation learning with deep convolutional generative adversarial networks. arXiv:1511.06434 (2015)

  10. Bakas, S., Akbari, H., Sotiras, A., Bilello, M., Rozycki, M., Kirby, J., et al.: Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic features. Sci Data 4 (2017). https://doi.org/10.1038/sdata.2017.117. Article No.170117

  11. Bakas, S., Akbari, H., Sotiras, A., Bilello, M., Rozycki, M., Kirby, J., at al.: Segmentation Labels and Radiomic Features for the Pre-operative Scans of the TCGA-GBM collection. The Cancer Imaging Archive (2017)

    Google Scholar 

  12. Bakas, S., Akbari, H., Sotiras, A., Bilello, M., Rozycki, M., Kirby, J., at al.: Segmentation Labels and Radiomic Features for the Pre-operative Scans of the TCGA-LGG collection. The Cancer Imaging Archive (2017)

    Google Scholar 

Download references

Acknowledgments

This work was supported by the National Basic Research Program of China (2015CB755500), the National Natural Science Foundation of China (11474071).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Yuanyuan Wang or Jinhua Yu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Li, Z., Wang, Y., Yu, J. (2018). Brain Tumor Segmentation Using an Adversarial Network. In: Crimi, A., Bakas, S., Kuijf, H., Menze, B., Reyes, M. (eds) Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2017. Lecture Notes in Computer Science(), vol 10670. Springer, Cham. https://doi.org/10.1007/978-3-319-75238-9_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-75238-9_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-75237-2

  • Online ISBN: 978-3-319-75238-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics