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Eyelid Tumor

Chapter

Abstract

A 55-year-old woman presented with a rapidly growing 1.5-cm ulcerated lesion on the right lower eyelid. Low-power microscopic section yielded a picture of a vaguely nodular dermal proliferation of lightly eosinophilic and vacuolated cells (Fig. 26.1). At intermediate power, the neoplastic nodules consisted of a random admixture of optically clear and eosinophilic stained cells (Fig. 26.2). High-power examination yielded vacuolated cells composed of hyperchromatic nuclei (Fig. 26.3).

Keywords

Sebaceous carcinoma Muir–Torre syndrome Sebocytes 

References

  1. 1.
    Abbas O, Mahalingam M. Cutaneous sebaceous neoplasms as markers of Muir-Torre syndrome: a diagnostic algorithm. J Cutan Pathol. 2009;26:613–9.CrossRefGoogle Scholar
  2. 2.
    Mugit MM, Foot B, Walters SJ, Mudhar HS, Roberts F, Rennie IG. Observational prospective cohort study of patients with newly-diagnosed ocular sebaceous carcinoma. Br J Ophthalmol. 2013;97:47–51.CrossRefGoogle Scholar
  3. 3.
    Shields JA, Demirci H, Marr BP, Eagle RC Jr, Stefanyszyn M, Shields CL. Conjunctival epithelia involvement by eyelid sebaceous carcinoma. Ophthal Plast Reconstr Surg. 2005;21:92–6.CrossRefPubMedGoogle Scholar
  4. 4.
    Ansai S, Takeichi H, Arase S, Kawana S, Kimura T. Sebaceous carcinoma: an immunohistochemical reappraisal. Am J Dermatopathol. 2011;33:579–87.CrossRefPubMedGoogle Scholar
  5. 5.
    Oster D, Prieto VG, Reed JA, Deavers MT, Lazar AJ, Ivan D. Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 177 cases. Mod Pathol. 2010;23:567–73.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media LLC 2018

Authors and Affiliations

  1. 1.American University of the Caribbean School of MedicineClermontUSA
  2. 2.Louisiana State University School of MedicineNew OrleansUSA

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