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Infections of the Ears, Nose, Throat, and Sinuses pp 317–327Cite as

Cervical Lymphadenitis in Children

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Abstract

Cervical lymphadenitis is a common complaint of childhood and most often indicates a local or systemic infectious etiology rather than malignancy or serious disease. Cervical lymphadenitis may present acutely (usually bacterial or viral in etiology), or follow an indolent course (for example atypical organisms, animal or vector-borne infections) leading to subacute/chronic lymphadenitis. A complete history (including exposure and dietary history) and physical examination are important to determine appropriate initial diagnostic evaluation and/or empiric therapy. High level imaging and surgical intervention may be indicated to prevent complications or achieve cure. The prognosis is excellent with most children making a complete recovery.

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References

  1. Healy CM, Baker CJ. Cervical lymphadenitis. In: Feigin and Cherry’s Textbook of Pediatric Infectious Diseases, 7th ed, Cherry JD, Harrison GJ, Kaplan SL, et al. (eds), Elsevier Saunder, Philadelphia 2014. p. 175-89.

    Google Scholar 

  2. Thorell EA. Cervical lymphadenitis and neck infections. In: Principles and Practice of Pediatric Infectious Diseases, 4th ed. Long SS, Pickering LK, Prober CG, (eds). Elsevier Saunders, Philadelphia 2012. p. 135–47.

    Google Scholar 

  3. Baker CJ. Group B streptococcal cellulitis-adenitis in infants. Am J Dis Child. 1982;136:631–3.

    PubMed  CAS  Google Scholar 

  4. Barton LL, Feigin RD. Childhood cervical lymphadenitis: a reappraisal. J Pediatr. 1974;84:846–52.

    Article  CAS  PubMed  Google Scholar 

  5. Cmejrek RC, Coticchia JM, Arnold JE. Presentation, diagnosis, and management of deep-neck abscesses in infants. Arch Otolaryngol Head Neck Surg. 2002;128:1361–4.

    Article  PubMed  Google Scholar 

  6. Coticchia JM, Getnick GS, Yun RD, Arnold JE. Age-, site-, and time-specific differences in pediatric deep neck abscesses. Arch Otolaryngol Head Neck Surg. 2004;130:201–7.

    Article  PubMed  Google Scholar 

  7. Worley ML, Seif JM, Whigham AS, Mims JW, Shetty AK, Evans AK. Suppurative cervical lymphadenitis in infancy: microbiology and sociology. Clin Pediatr (Phila). 2015;54:629–34.

    Article  Google Scholar 

  8. Gerber JS Coffin SE, Smathers SA, Zaoutis TE. Trend in the incidence of methicillin-resistant Staphylococcus aureus infections in children’s hospitals in the United States. Clin Infect Dis. 2009;49:65–71.

    Article  PubMed  Google Scholar 

  9. Duggal P, Naseri I, Sobol SE. The increased risk of community-acquired methicillin-resistant Staphylococcus aureus in young children. Laryngoscope. 2012;121:51–5.

    Article  Google Scholar 

  10. American Academy of Pediatrics. Plague. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 624–6.

    Google Scholar 

  11. Kwit N, Nelson C, Kugeler K, et al. Human plague-United States, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:918–9.

    Article  PubMed  Google Scholar 

  12. American Academy of Pediatrics. Tuleremia. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 839–41.

    Google Scholar 

  13. World Health Organization. Diphtheria detected in Spain. http://www.euro.who.int/en/health-topics/disease-prevention/vaccines-and-immunization/news/news/2015/06/diphtheria-detected-in-spain.

  14. American Academy of Pediatrics. Tuberculosis. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 805–31.

    Google Scholar 

  15. American Academy of Pediatrics. Diseases caused by nontuberculous mycobacteria. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases, 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 831–9.

    Google Scholar 

  16. Armstrong KL, James RW, Dawson DJ, et al. Mycobacterium haemophilum causing perihilar or cervical lymphadenitis in healthy children. J Pediatr. 1992;121:202–5.

    Article  CAS  PubMed  Google Scholar 

  17. American Academy of Pediatrics. Toxoplasma gondii infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 787–96.

    Google Scholar 

  18. American Academy of Pediatrics. Cat-scratch disease. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 280–3.

    Google Scholar 

  19. Margileth AM, Wear DJ, Hadfield TL, et al. Cat-scratch disease: bacteria in skin at the primary inoculation site. JAMA. 1984;252:928–31.

    Article  CAS  PubMed  Google Scholar 

  20. Zangwill KM, Hamilton DH, Perkins BA, et al. Cat scratch disease in Connecticut: epidemiology—risk factors, and evaluation of a new diagnostic test. N Engl J Med. 1993;329:8–13.

    Article  CAS  PubMed  Google Scholar 

  21. Rajasekaran K, Krakovitz P. Enlarged neck lymph nodes in children. Pediatr Clin N Am. 2013;60:923–36.

    Article  Google Scholar 

  22. Rosenberg TL, Nolder AR. Pediatric cervical lymphadenopathy. Otolaryngol Clin N Am. 2014;47:721–31.

    Article  Google Scholar 

  23. Sundaresh HP, Kumar A, Hokanson JT, et al. Etiology of cervical lymphadenitis in children. Am Fam Physician. 1981;24:147–51.

    PubMed  CAS  Google Scholar 

  24. American Academy of Pediatrics. Group B Streptococcal infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 745–50.

    Google Scholar 

  25. Albanyan EA, Baker CJ. Is lumbar puncture necessary to exclude meningitis in neonates and young infants: lessons from the group B streptococcus cellulitis – adenitis syndrome. Pediatrics. 1998;102:985–6.

    Article  CAS  PubMed  Google Scholar 

  26. American Academy of Pediatrics. Diphtheria. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 325–9.

    Google Scholar 

  27. McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation. 2017;135:e927–99.

    Article  PubMed  Google Scholar 

  28. American Academy of Pediatrics. Kawasaki disease. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 494–500.

    Google Scholar 

  29. American Academy of Pediatrics. Epstein Barr virus infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 336–40.

    Google Scholar 

  30. American Academy of Pediatrics. Cytomegalovirus infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015: 317–322.

    Google Scholar 

  31. American Academy of Pediatrics. Adenovirus infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 226–8.

    Google Scholar 

  32. American Academy of Pediatrics. Human herpesvirus 6 (including Roseola) and 7. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015: 449–452.

    Google Scholar 

  33. American Academy of Pediatrics. Enterovirus (nonpoliovirus). In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 333–6.

    Google Scholar 

  34. Carithers HA. Cat-scratch disease: an overview based on a study of 1200 patients. Am J Dis Child. 1985;139:1124–33.

    Article  CAS  PubMed  Google Scholar 

  35. Carithers HA, Carithers CM, Edwards RO Jr. Cat-scratch disease: its natural history. JAMA. 1969;207:312–6.

    Article  CAS  PubMed  Google Scholar 

  36. Carithers HA. Oculoglandular disease of Parinaud: a manifestation of cat-scratch disease. Am J Dis Child. 1978;132:1195–200.

    Article  CAS  PubMed  Google Scholar 

  37. American Academy of Pediatrics. Nocardiosis. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 571–2.

    Google Scholar 

  38. Marshall GS, Edwards KM, Butler J, et al. Syndrome of periodic fever, pharyngitis, and aphthous stomatitis. J Pediatr. 1987;110:43–6.

    Article  CAS  PubMed  Google Scholar 

  39. American Academy of Pediatrics. Arcanobacterium haemolyticum infections. In: Kimberlin DW, Brady MT, Jackson M, Long SS, editors. Red book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2015. p. 246–7.

    Google Scholar 

  40. Davis SD, Comstock GW. Mycobacterial cervical adenitis in children. J Pediatr. 1961;58:771–8.

    Article  CAS  PubMed  Google Scholar 

  41. Flint D, Mahadevan M, Barber C, et al. Cervical lymphadenitis due to non-tuberculous mycobacteria: surgical treatment and review. Int J Pediatr Otorhinolaryngol. 2000;53:187–94.

    Article  CAS  PubMed  Google Scholar 

  42. Lindeboom JA. Surgical treatment for nontuberculous mycobacterial (NTM) cervicofacial lymphadenitis in children. J Oral Maxillofac Surg. 2012;70:345–8.

    Article  PubMed  Google Scholar 

  43. Zimmermann P, Tebruegge M, Curtis N, Ritz N. The management of non-tuberculous cervicofacial lymphadenitis in children: a systematic review and meta-analysis. J Infect. 2015;71:9–18.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Infectious Diseases Section, Baylor College of Medicine, Houston, TX, USA

    C. Mary Healy

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  1. C. Mary Healy
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Correspondence to C. Mary Healy .

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Editors and Affiliations

  1. Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

    Marlene L. Durand

  2. Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA

    Daniel G. Deschler

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Healy, C.M. (2018). Cervical Lymphadenitis in Children. In: Durand, M., Deschler, D. (eds) Infections of the Ears, Nose, Throat, and Sinuses. Springer, Cham. https://doi.org/10.1007/978-3-319-74835-1_26

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  • DOI: https://doi.org/10.1007/978-3-319-74835-1_26

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  • Print ISBN: 978-3-319-74834-4

  • Online ISBN: 978-3-319-74835-1

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