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Numerical Basics of Bioimpedance Measurements

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Bioimpedance in Biomedical Applications and Research

Abstract

Fundamental issues in various areas of bioimpedance application, such as impedance cardiography, electrical impedance tomography, and bioimpedance analysis of body composition and spectroscopy, require mathematical models. Highly inhomogeneous and anisotropic structure of the human body makes the numerical simulation of bioimpedance measurements the inevitable tool. In this chapter, we present essential elements and the workflow of the finite element method (FEM)-based computational technology in bioimpedance modeling: 3D image segmentation, adaptive mesh generation, finite element discretization, as well as construction and visualization of current density, potential, and sensitivity fields. The cornerstone of the technology is an anatomically correct 3D model of the human body from the Visible Human Project (VHP). The technology provides an online numerical simulator of bioimpedance measurements using a conventional 4-electrode and 10-electrode placement schemes.

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Acknowledgements

The authors thank V.Yu. Salamatova, V.K. Kramarenko, and A.S. Yurova for segmentation of the VHP data and performing numerical experiments, G.V. Kopytov for the development of user’s interface for the online numerical simulator, and D.V. Nikolaev and A.V. Smirnov for problem formulation, valuable discussion, and financial support of the initial part of this study. Our work was supported by the Russian Foundation for Basic Research (RFBR grants 17-01-00886 and 17-51-53160).

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Danilov, A., Rudnev, S., Vassilevski, Y. (2018). Numerical Basics of Bioimpedance Measurements. In: Simini, F., Bertemes-Filho, P. (eds) Bioimpedance in Biomedical Applications and Research. Springer, Cham. https://doi.org/10.1007/978-3-319-74388-2_8

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  • DOI: https://doi.org/10.1007/978-3-319-74388-2_8

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