Institutionalising the Medical Evaluation of CAM: Dietary and Herbal Supplements as a Peculiar Example of (Differential) Legitimisations of CAM in the USA

  • Geoffroy Carpier
  • Patrice Cohen
Chapter
Part of the Health, Technology and Society book series (HTE)

Abstract

In this chapter, we present a specific aspect of our socio-anthropological research focusing on the federal institutionalisation of CAM in the USA: the case of ‘dietary and herbal supplements’ (D/HS). We show how the case provides a good example of different and specific configurations of medical research on CAM since the 1990s through the creation of three federal entities. Based on an analysis of controversies and challenges around specific ‘D/HS’, we interrogate the manners in which a plurality of federal and non-federal agents involved in this mixed social space collaborates and competes on the medical evaluation of CAM—particularly around ideas of efficacy, safety, authenticity, and integration—shaping and re-shaping the places they assign to CAM within the broader American health system.

Notes

Acknowledgements

This research was funded by the French National Cancer Institute (INCa) from January 2015 to January 2018.

References

  1. Atlani-Duault, L. (2009). Au Bonheur des autres: anthropologie de l’aide humanitaire. Paris: Armand Colin.Google Scholar
  2. Baszanger, I. (1986). Les maladies chroniques et leur ordre négocié. Revue Française de Sociologie, 27(1), 3–27.CrossRefGoogle Scholar
  3. Bothwell, L. E., & Podolsky, S. H. (2016). The history of clinical trials: The emergence of the randomized, controlled trial. New England Journal of Medicine, 375, 501–504.CrossRefGoogle Scholar
  4. Bourret, P., & Le Moigne, P. (2014). Essais cliniques, production de la preuve et mutation de la biomédecine. Sciences sociales et santé, 3(32), 5–11.CrossRefGoogle Scholar
  5. Cambrosio, A., & Keating, P. (2008). Cancer clinical trials: The emergence and development of a new style of practice. In D. Cantor (Ed.), Cancer in the twentieth century (pp. 197–223). Baltimore: Johns Hopkins University Press.Google Scholar
  6. Cambrosio, A., Keating, P., & Nelson, N. (2014). Régimes thérapeutiques et dispositifs de preuves en oncologie: l’organisation des essais cliniques, des groupes coopérateurs aux consortiums de recherche. Sciences sociales et santé, 3(32), 13–42.CrossRefGoogle Scholar
  7. Castel, P., & Friedberg, E. (2010). Institutional change as an interactive process: The case of the modernization of the French Cancer Centers. Organization Science, 21(2), 311–330.CrossRefGoogle Scholar
  8. Chen, N. (2009). Food, medicine, and the quest for good health. New York: Columbia University Press.Google Scholar
  9. Dubet, F. (2002). Le déclin de l’institution. Paris: Le Seuil.Google Scholar
  10. Foster, S. (2011). A brief history of adulteration of herbs, spices, and botanical drugs. HerbalGram, 92, 42–57.Google Scholar
  11. Fuselier, B., & Marquis, N. (2009). Transaction sociale et négociation: deux notions à articuler. Négociations, 2(12), 23–33.CrossRefGoogle Scholar
  12. Hess, D. J. (1999). Evaluating alternative cancer therapies: A guide to the science and politics of an emerging medical field. New Brunswick: Rutgers University Press.Google Scholar
  13. Hess, D. J. (2002). The raw and the organic: Politics of therapeutic cancer diets in the United States. The Annals of the American Academy of Political and Social Science, 583(1), 76–96.CrossRefGoogle Scholar
  14. Jasanoff, S. (1990). The fifth branch: Science advisers as policymakers. Cambridge, MA and London: Harvard University Press.Google Scholar
  15. Jütte, R. (2001). Alternative medicine and medico-historical semantics. In R. Jütte, M. Eklöf, & M. C. Nelson (Eds.), Historical aspects of unconventional medicine – Approaches, concepts, case studies (pp. 11–26). Sheffield: European Association for the History of Medicine and Health Publications.Google Scholar
  16. Lee, M. R. (2011). The history of ephedra (Ma-Huang). Journal of the Royal College of Physicians of Edinburgh, 41(1), 78–84.CrossRefGoogle Scholar
  17. Markle, G. E., & Petersen, J. C. (1980). Politics, science, and cancer: The laetrile phenomenon. Boulder, CO: Westview Press.Google Scholar
  18. Marks, H. (1997). The progress of experiment: Science and therapeutic reform in the United States (1900–1990). Cambridge: Cambridge University Press.Google Scholar
  19. Meimon, J. (2011). Sur le fil. La naissance d’une institution. In M. Offerlé & J. Lagroye (Eds.), Sociologie de l’institution (pp. 105–129). Paris: Belin.Google Scholar
  20. Meldrum, M. L. (2000). A brief history of the randomized controlled trial. From oranges and lemons to the gold standard. Hematology/Oncology Clinics of North America, 14(4), 745–760.CrossRefGoogle Scholar
  21. Micollier, E. (2011). Un savoir thérapeutique hybride et mobile. Éclairage sur la recherche médicale en médecine chinoise en Chine aujourd’hui. Revue d’anthropologie des connaissances, 1(5), 41–70.CrossRefGoogle Scholar
  22. Offerlé, M., & Lagroye, J. (Eds.). (2011). Sociologie de l’institution. Paris: Belin.Google Scholar
  23. Olivier de Sardan, J. P. (2008). La rigueur du qualitatif: les contraintes empiriques de l’interprétation socio-anthropologique. Lauvain-la-Neuve: Academia-Bruylant.Google Scholar
  24. Petryna, A. (2009). When experiments travel: Clinical trials and the global search for human subjects. Princeton: Princeton University Press.CrossRefGoogle Scholar
  25. Smith, M. E. (1992). The Burzynski controversy in the United States and in Canada: A comparative case study in the sociology of alternative medicine. The Canadian Journal of Sociology/Cahiers Canadiens De Sociologie, 17(2), 133–160.CrossRefGoogle Scholar
  26. Strauss, A. (1978). Negotiations: Varieties, contexts, processes, and social order. San Francisco: Jossey-Bass.Google Scholar

Sources

    Institutional Archives

    1. NCCAM unprocessed archives at the Office of NIH History and National Library of MedicineGoogle Scholar

Institutional Corpus

  1. NCCIH-NCCAM:Google Scholar
  2. Congressional JustificationsGoogle Scholar
  3. Minutes of the National Advisory Council for Complementary and Integrative Health Press ReleasesGoogle Scholar
  4. Strategic PlansGoogle Scholar

Other Sources

  1. Abrams, D. et al. (2015). PRIMIER: A National Integrative Medicine Database. The Bravewell Collaborative.Google Scholar
  2. Banerji, P., et al. (2008). Cancer patients treated with the Banerji protocols utilising homoeopathic medicine: A best case series program of the National Cancer Institute USA. Oncology Reports, 20(1), 69–74.Google Scholar
  3. Barnes, P. M., Blume, B., & Nahin, R. (2008). CDC national health statistics report #12. In Complementary and alternative medicine use among adults and children: United States, 2007. Atlanta: Centers for Disease Control.Google Scholar
  4. Berman, B. M., & Larson, D. B. (1995). Alternative medicine: Expanding medical horizon: A report to the National Institutes of Health on alternative medical systems and Practices in the United States (pp. 30–34). Washington, DC: US GPO.Google Scholar
  5. Bodley, H. (2003). Medical examiner: Ephedra a factor in Blecher death. USA Today. Google Scholar
  6. Burton, T. M. (2000). In trials, potion of herbs slows prostate cancer. Wall Street Journal, B1.Google Scholar
  7. Burton, T. M. (2002). Recall of herbal supplement highlights gaps in regulation. Wall Street Journal.Google Scholar
  8. Chan, T. Y., Chan, J. C., Tomlinson, B., & Critchley, J. A. (1993). Chinese herbal medicines revisited: A Hong Kong perspective. Lancet, 342(8886–8887), 1532–1534.CrossRefGoogle Scholar
  9. Cheng, Y. C. (2011). Why and how to globalize traditional Chinese medicine. Journal of Traditional and Complementary Medicine, 1(1), 1–4.CrossRefGoogle Scholar
  10. Clarke, T. C., Black, L. I., Stussman, B. J., Barnes, P. M., & Nahin, R. L. (2015). Trends in the use of complementary health approaches among adults: United States, 2002–2012. National Health Statistics Reports, 79, 1.Google Scholar
  11. Congressional findings related to dietary supplements health and education act of 1994, Pub. L. No. 103–417, § 2, 15 (A), 108 Stat. 4325; 4326, Oct. 25, 1994.Google Scholar
  12. Connolly, D. (2008). Steve Blecher’s Death Five Years Later. Baltimore Sun.Google Scholar
  13. Cumberford, G. (2012). EMI vs EMA: ‘Economically motivated integrity’ vs. economically motivated adulteration in the natural products supply chain. HerbalGram, 94, 40–41.Google Scholar
  14. DiPaola, R. S., Zhang, H., Lambert, G. M., et al. (1998). Clinical and biological activity of an estrogenic herbal combination (PC- SPES) in prostate cancer. New England Journal of Medicine, 339, 785–791.CrossRefGoogle Scholar
  15. DSHEA, 21 U.S.C. § 321 (ff) (I) (A)–(F), 1994.Google Scholar
  16. Eisenberg, D. M., Kessler, R. C., Foster, C., Norlock, F. E., Calkins, D. R., & Del-Banco, T. L. (1993). Unconventional medicine in the United States: Prevalence, costs, and patterns of use. New England Journal of Medicine, 328(4), 246–252.CrossRefGoogle Scholar
  17. FDA. (2004). FDA issues regulation prohibiting sale of dietary supplements containing ephedrine alkaloids and reiterates its advice that consumers stop using these products. FDA Press Release.Google Scholar
  18. FDA. (2009). Warning Letter, Burzynski Research Institute/IRB. ref: 10-HFD-45-09-0.Google Scholar
  19. FDA. (2010). Advancing regulatory science for public health. Washington, DC: U.S. GPO.Google Scholar
  20. FDA, Center for Drug Evaluation and Research. (2004). Guidance for industry: Botanical drug products. Washington, DC: U.S. GPO.Google Scholar
  21. Fontanarosa, P. B., Rennie, D., & DeAngelis, C. D. (2003). The need for regulation of dietary supplements – Lessons from ephedra. JAMA, 289(12), 1568–1570.CrossRefGoogle Scholar
  22. Haller, C. A., & Benowitz, N. L. (2000). Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. New England Journal of Medicine, 343(25), 1833–1838.CrossRefGoogle Scholar
  23. Hopp, C. (2015). Past and future research at national centre for complementary and integrative health (NCCIH) with respect to botanicals. HerbalGram, 107, 44–51.Google Scholar
  24. Jonas, W. (2005). Building an evidence house: Challenges and solutions to research in complementary and alternative medicine. Forsch Komplementärmed Klass Naturheilkd, 12(3), 159–167.Google Scholar
  25. Mansky, P. J., & Straus, S. E. (2002). St John’s wort: More implications for cancer patients. Journal of the National Cancer Institute, 94(16), 1187–1188.CrossRefGoogle Scholar
  26. Miller, F. G., Emanuel, E. J., Rosenstein, D. L., & Straus, S. E. (2004). Ethical issues concerning research in complementary and alternative medicine. JAMA, 291(5), 599–604.CrossRefGoogle Scholar
  27. New York Times. (1993). The 1993 Snake Oil Protection Act. New York Times, October 5.Google Scholar
  28. Public Citizens’ Health Research Group. (2001). Petition requesting a ban of Ephedra.Google Scholar
  29. Ron, H. J., Verweij, M. J., de Bruijn, P., Loos, W. J., & Sparreboom, A. (2002). Effects of St. John’s wort on irinotecan metabolism. Journal of the National Cancer Institute, 94(16), 1247–1249.CrossRefGoogle Scholar
  30. Seifried, H. E., Sorkin, B. C., & Costello, R. B. (2004). Free radicals: The pros and cons if antioxidants – Summary report of the National Institutes of Health symposium. The Journal of Nutrition, 134(11), 3143–3163.CrossRefGoogle Scholar
  31. U.S. Department of Health and Human Services, Food and Drug Administration Center for Drug Evaluation and Research. (2004). Guidance for industry: Botanical drug products. Washington DC: U.S. GPO.Google Scholar
  32. U.S. Department of Health and Human Services, Office of Inspector General. (2001). Adverse event reporting for dietary supplements: An inadequate safety valve. Washington, DC: U.S. GPO.Google Scholar
  33. Wang, L., & Arnold, K. (2002). Press release herbal dietary supplement alters metabolism of chemotherapy drug. Journal of the National Cancer Institute, 94(16), 1183.CrossRefGoogle Scholar
  34. Wolfe, S. (2003). Ephedra – Scientific evidence versus money/politics. Science, 300(5618), 437.CrossRefGoogle Scholar
  35. Zia, F., & White, J. (2009). Letter to the Editor. Integrative Cancer Therapies, 8(2), 113–114.CrossRefGoogle Scholar

Copyright information

© The Author(s) 2018

Authors and Affiliations

  • Geoffroy Carpier
    • 1
  • Patrice Cohen
    • 1
  1. 1.Université de RouenMont Saint AignanFrance

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