Autoimmune Thyroid Disease

  • Jessica R. Smith
  • Stephen A. Huang


Autoimmune thyroid disease affects approximately 2% of the female population and 0.2% of the male population. Its overall prevalence peaks in adulthood, but it is also the most common etiology of acquired thyroid dysfunction in pediatrics. This chapter presents a summary of autoimmune thyroid disease, discussing chronic autoimmune thyroiditis and Graves’ disease, with an emphasis on their clinical management. Normal levels of thyroid hormone are critical to neurodevelopment and growth, and by maintaining an appropriate index of suspicion, the clinician can often recognize thyroid dysfunction in its early stages.


Thyroid Hypothyroidism Hyperthyroidism Autoimmune Hashimoto’s disease Graves’ disease Thyroiditis 



We are indebted to Dr. Reed Larsen, Chief of the Brigham and Women’s Hospital Thyroid Section in Boston, for helpful comments and assistance in the review of this chapter.


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Thyroid Program, Medicine/EndocrinologyBoston Children’s HospitalBostonUSA
  2. 2.Pediatrics, Medicine/Endocrinology DepartmentBoston Children’s HospitalBostonUSA

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