Contributors to Differences between Mixed and Central Venous Oxygen Saturation
Mixed venous oxygen saturation (SvO2) represents the relationship between systemic oxygen delivery (DO2) and consumption (VO2) and, therefore, the adequacy of oxygen supply to the tissues . SvO2 reflects the total amount of oxygen contained in the blood that returns to the right heart through the superior vena cava, inferior vena cava (IVC) and coronary sinus . Whereas SvO2 can only be obtained by right heart catheterization, central venous oxygen saturation (ScvO2) can be measured using a central venous catheter (CVC), which is easier to place, cheaper, and is assumed to have fewer complications than a pulmonary artery catheter (PAC) . Since the use of PAC in critically ill patients has declined , ScvO2 has been used as a surrogate of SvO2 . ScvO2 represents the blood oxygen saturation at the drainage from the superior or the inferior vena cava into the right atrium, depending on catheter position [5, 6].
The underlying assumption for using ScvO2as...
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