Skip to main content
SpringerLink
Log in

Sleep Issues in Myopathic Disorders and Muscular Dystrophies

  • Chapter
  • First Online:
Sleep Issues in Neuromuscular Disorders

  • 523 Accesses

Abstract

Myopathies and muscular dystrophies are disease inherent to muscles and have the common feature of muscle weakness. Multiple sleep disorders are associated with them. Sleep disordered breathing disorder (SRBD) is the most common sleep disorder in both myopathies and muscular dystrophies. Various different factors contributed to the development of SRBD that include diaphragmatic involvement, coexisting cardiac abnormalities, reduction in lung volumes and capacities, and airway obstruction. Other sleep disorders in these conditions include insomnia, restless legs syndrome, hypersomnolence, and parasomnias.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 99.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fermin AM, Afzal U, Culebras A. Sleep in neuromuscular diseases. Sleep Med Clin. 2016;11(1):53–64. https://doi.org/10.1016/j.jsmc.2015.10.005.Epub2016Jan9.

    Article  PubMed  Google Scholar 

  2. Peppard PE, Young T, Hla KM. Increased prevalence of sleep-disorderd breathing in adults. Am J Epidemiol. 2013;177(9):1006–14.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Arens R, Muzumdar H. Sleep, Sleep disordered breathing, and nocturnal hypoventilation in children with Neuromuscular diseases. Pediatr Respir Rev. 2010;11(1):24.

    Article  Google Scholar 

  4. Phillips MF, Smith PE, Carroll N, Calverley PM. Nocturnal oxygenation and prognosis in Duchenne muscular dystrophy. Am J Respir Crit Care Med. 1999;160(1):198–202.

    Article  CAS  PubMed  Google Scholar 

  5. Aboussouan LS. Sleep-disordered breathing in neuromuscular disease. Am J Respir Crit Care Med. 2015;191(9):979–89.

    Article  PubMed  Google Scholar 

  6. Hudgel DW, Devadatta P. Decrease in functional residual capacity during sleep in normal humans. J Appl Physiol. 1984;57:1319–22.

    Article  CAS  PubMed  Google Scholar 

  7. Ibanez J, Raurich JM. Normal values of functional residual capacity in the sitting and supine positions. Intensive Care Med. 1982;8:173–7.

    Article  CAS  PubMed  Google Scholar 

  8. Appleberg J, Nordahl G, Janson C. Lung volume and its correlation to nocturnal apnoea and desaturation. Respir Med. 2000;94:233–9.

    Article  Google Scholar 

  9. Van de Graff WB. Thoracic influence on upper airway patency. J Appl Physiol (1985). 1988;65:2124–31.

    Article  Google Scholar 

  10. White JE, Drinnan MJ, Smithson AJ, Griffiths CJ, Gibson GJ. Respiratory muscle activity and oxygenation during sleep in patients with muscular weakness. Eur Respir J. 1989;2:26–30.

    Google Scholar 

  11. Smith PE, Edwards RH, Claverly PM. Mechanisms of sleep-disordered breathing in chronic neuromuscular disease: implications for management. Q J Med. 1991;81:961–73.

    Article  CAS  PubMed  Google Scholar 

  12. McCool FD, Tzelepis GE. Dysfunction of the diaphragm. N Engl J Med. 2012;366:932–42.

    Article  CAS  PubMed  Google Scholar 

  13. Shahrizaila N, Kinnear WJM, Wills AJ. Respiratory involvement in inherited primary muscle conditions. J Neurol Neurosurg Psychiatry. 2006;77(10):1108–15.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Ferrerio A, Quijano-Roy S, Piche C. Mutations of the Selenoprotein N gene, which is implicated in rigid spine muscular dystrophy, cause the classical phenotype of multiminicore disease: reassessing the nosology of early-onset myopathies. Am J Hum Genet. 2002;71(4):739–49. https://doi.org/10.1086/342719.

    Article  Google Scholar 

  15. Mellies U, Ragette R, Schwake C. Sleep disordered breathing and respiratory failure in acid maltase deficiency. Neurology. 2001;57(7):1290–5.

    Article  CAS  PubMed  Google Scholar 

  16. Teixeira A, Cherin P, Similowski T. Diaphragmatic dysfunction in patients with idiopathic inflammatory myopathies. Neuromuscul Disord. 2005;15(1):32–9. https://doi.org/10.1016/j.nmd.2004.09.006.

    Article  PubMed  Google Scholar 

  17. Latronico N, Bolton C. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol. 2011;10(10):931–41. https://doi.org/10.1016/S1474-4422(11)70178-8.

    Article  PubMed  Google Scholar 

  18. Madej-Pilarczyk A, Kochanski A. Emery-Dreifuss muscular dystrophy: the most recognizable laminopathy. Folia Neuopathol. 2016;54(1):1–8.

    CAS  Google Scholar 

  19. Sveen M-L, Thune JJ, Keber L. Cardiac involvement in patients with Limb-Girdle Muscular Dystrophy Type 2 and Becker muscular dystrophy. Arch Neurol. 2008;65(9):1196–201. https://doi.org/10.1001/arch-neur.65.9.1196.

    Article  PubMed  Google Scholar 

  20. van der Kooi AJ, Van Meegen M, Bolhuis PA. Genetic localization of a newly recognized autosomal dominant limb-girdle muscular dystrophy with cardiac involvement (LGMD1B) to chromosome 1q11-21. Am J Hum Genet. 1997;60:891–5.

    PubMed  PubMed Central  Google Scholar 

  21. Perloff JK, Stevenson WG, Weiss J. Cardiac involvement in myotonic muscular dystrophy: a prospective study of 25 patients. Am J Cardiol. 1984;54(8):1074–81. https://doi.org/10.1016/S0002-9149(84)80147-2.

    Article  CAS  PubMed  Google Scholar 

  22. Zhang LH, Fang LG, Cheng ZW, Fang Q. Cardiac manifestations of patients with mitochondrial disease. Zhonghua Xin Xue Guan Bing Za Zhi. 2009;37(10):892–5.

    PubMed  Google Scholar 

  23. Muller-Hocker J, Schafer S, Mendel B, Lochmuller H, Pongratz D. Nemaline cardiomyopathy in a young adult: an ultraimmunohistochemical study and review of literature. Ultrastruct Pathol. 2000;24(6):407–16.

    Article  CAS  PubMed  Google Scholar 

  24. Banwell BL, Becker LE, Jay V, et al. Cardiac manifestations of congenital fiber-type disproportion myopathy. J Child Neurol. 1999;14(2):83–7.

    Article  CAS  PubMed  Google Scholar 

  25. Lanfranchi PA, Braghiroli A, Giannuzzi P. Prognostic value of nocturnal Cheyne-Stokes respiration in chronic heart failure. Circulation. 1999;99:1435–40.

    Article  CAS  PubMed  Google Scholar 

  26. Muller C, Jones H, O’Grady G, Suzrez A, Heller J, Kishnani P. Language and speech function in children with infantile Pompe disease. J Pediatr Neurol. 2009;7:147–56.

    Google Scholar 

  27. Renard D, Humbertclaude V, Labauge P. Macroglossia in adult Duchenne muscular dystrophy. Acta Neurol Belg. 2010;110:288.

    CAS  PubMed  Google Scholar 

  28. Khan Y, Heckmatt JZ. Obstructive apnoeas in Duchenne muscular dystrophy. Thorax. 1994;49:157–61.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Suresh S, Wales P, Cooper DG. Sleep-related breathing disorder in Duchenne muscular dystrophy: disease spectrum in pediatricpopulation. J Paediatr Child Health. 2005;41:500–3.

    Article  PubMed  Google Scholar 

  30. Leonardis L, Blague R, Dolenc Groselj L. Sleep and breathing disorders in myotonic dystrophy type 2. Acta Neurol Scand. 2015;132:42–8.

    Article  CAS  PubMed  Google Scholar 

  31. Bianchi MLE, Losurdo A, Silvestri G. Prevalence and clinical correlates of sleep disordered breathing in myotonic dystrophy types 1 and 2. Sleep Breath. 2014;18:579–89. https://doi.org/10.1007/s11325-013-0921-5.

    Article  PubMed  Google Scholar 

  32. Beetar JT, Guilmette TJ, Sparadeo FR. Sleep and pain complaints in symptomatic traumatic brain injury and neurologic populations. Arch Phys Med Rehabil. 1996;77(12):1298–302.

    Article  CAS  PubMed  Google Scholar 

  33. Hoffman AJ, Given BA, Von Eye A. Relationships among pain, fatigue, insomnia and gender in persons with lung cancer. Oncol Nurs Forum. 2007;34(4):785–92.

    Article  PubMed  Google Scholar 

  34. Jennum P, Drewes AM, Andreasen A, Nielsen KD. Sleep and other symptoms in primary fibromyalgia and in healthy controls. J Rheumatol. 1993;20(10):1756–9.

    CAS  PubMed  Google Scholar 

  35. Power JD, Perrucio AV, Badley EM. Pain as a mediator of sleep problems in arthritis and other chronic conditions. Arthritis Rheum. 2005;53(6):911–9.

    Article  PubMed  Google Scholar 

  36. Della Marca G, Frusciante R, Vollono C, Ricci E. Pain and the alpha-sleep anomaly: a mechanism of sleep disruption in fascioscapulohumeral muscular dystrophy. Pain Med. 2013;14(4):487–97. https://doi.org/10.1111/pme.12054.

    Article  PubMed  Google Scholar 

  37. Bushby KM, Pollitt C, Johnson MA, Chinnery PF. Muscle pain as a prominent feature of FSHD: four illustrative case reports. Neuromuscul Disord. 1998;8(8):574–9.

    Article  CAS  PubMed  Google Scholar 

  38. Vianello A, Bevilacqua M, Vincenti E. Long-term nasal intermittent positive pressure ventilation in advanced Duchenne’s muscular dystrophy. Chest. 1994;105(2):445–8.

    Article  CAS  PubMed  Google Scholar 

  39. Mendell JR, Moxley RT, Florence J. Randomized, double-blind six-month trial of prednisone in Duchenne’s muscular dystrophy. N Engl J Med. 1989;320(24):1592–7.

    Article  CAS  PubMed  Google Scholar 

  40. Lam EM, Shepard PW, Milone M. Restless legs syndrome and daytime sleepiness are prominent in myotonic dystrophy type 2. Neurology. 2013;81(2):157–64. https://doi.org/10.1212/WNL.0b013e31829a340f.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Ekbom K, Ulfberg J. Restless legs syndrome. J Intern Med. 2009;266(5):419–31. https://doi.org/10.1111/j.1365-2796.2009.02159.

    Article  CAS  PubMed  Google Scholar 

  42. Salas RE, Gamaldo CE, Allen RP. Update in restless legs syndrome. Curr Opin Neurol. 2010;23(4):401–6. https://doi.org/10.1097/WCO.0b013e32833bcdd8.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Akamine RT, Grossklauss LF, Tufik S. Restless leg syndrome exacerbated by amytriptiline in a patient with Duchenne muscular dystrophy. Sleep Sci. 2014;7(3):178–80. https://doi.org/10.1016/j.slsci.2014.09.010. Epub 2014 Sep 27

    Article  PubMed  PubMed Central  Google Scholar 

  44. Dauvilliers YA, Laberge L. Myotonic dystrophy type 1, daytime sleepiness and REM sleep dysregulation. Sleep Med Rev. 2012;16(6):539–45. https://doi.org/10.1016/j.smrv.2012.01.001. Epub 2012 Mar 31

    Article  PubMed  Google Scholar 

  45. Yu H, Laberge L, Dauvilliers Y. Daytime sleepiness and REM sleep characteristics in myotonic dystrophy: a case-control study. Sleep. 2011;34(2):165–70.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Schneider-Gold C, Bellenberg B, Lukas C. Cortical and subcortical grey and white matter atrophy in myotonic dystrophies type 1 and 2 is associated with cognitive impairment, depression and daytime sleepiness. PLoS One. 2015;10(6):e0130352.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Romigi A, Albanese M, Massa R. Sleep-wake cycle and daytime sleepiness in the myotonic dystrophies. J Neurodegener Dis. 2013;2013:692026.

    CAS  PubMed  PubMed Central  Google Scholar 

  48. Chokroverty S, Bhat S, Rosen D, Farheen A. REM behavior disorder in myotonic dystrophy type 2. Neurology. 2012;78(24):2004. https://doi.org/10.1212/WNL.0b013e318259e28c.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neurology and Sleep Medicine, University of South Dakota-Sanford School of Medicine, Sioux Falls, SD, USA

    Valentina Joseph M.D.

  2. University of Missouri, Columbia, MO, USA

    Joe Devasahayam M.D.

  3. Department of Neurology, University of Missouri, Columbia, MO, USA

    Munish Goyal M.D.

Authors
  1. Valentina Joseph M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Joe Devasahayam M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Munish Goyal M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Neurology, University of Missouri, Columbia, Missouri, USA

    Raghav Govindarajan

  2. Department of Neurology, University of Missouri , Columbia, Missouri, USA

    Pradeep C. Bollu

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Joseph, V., Devasahayam, J., Goyal, M. (2018). Sleep Issues in Myopathic Disorders and Muscular Dystrophies. In: Govindarajan, R., Bollu, P. (eds) Sleep Issues in Neuromuscular Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-73068-4_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-73068-4_4

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-73067-7

  • Online ISBN: 978-3-319-73068-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation