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Pyoderma Gangrenosum

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Neutrophilic Dermatoses

Abstract

Pyoderma gangrenosum (PG), one of the most impressive cutaneous conditions, is an inflammatory ulceration with a distinctive clinical appearance, often associated with systemic diseases. Considerations on the significance of pyoderma gangrenosum, both in its classic ulcerative form and in its clinical variants, led to its inclusion among the spectrum of the neutrophilic dermatoses. Ongoing research aims at identifying genetic factors favoring PG, as well as deciphering the mechanisms of inflammation in PG.

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Acknowledgement

I am indebted to Professor Frank Powell, MD, for fruitful and friendly discussions, in addition to his outstanding writings and lectures on pyoderma gangrenosum.

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  1. Physician (Hon.) of Paris Hospitals, Paris, France

    Daniel Wallach

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  1. Daniel Wallach
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  1. Physician (Hon.) of Paris Hospitals, Paris, France

    Daniel Wallach

  2. Pathology Department, APHP Hôpital Saint Louis, Paris, France

    Marie-Dominique Vignon-Pennamen

  3. Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita’ degli Studi di Milano, Unita’ Operativa di Dermatologia, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, Milano, Italy

    Angelo Valerio Marzano

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Wallach, D. (2018). Pyoderma Gangrenosum. In: Wallach, D., Vignon-Pennamen, MD., Valerio Marzano, A. (eds) Neutrophilic Dermatoses. Springer, Cham. https://doi.org/10.1007/978-3-319-72649-6_6

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