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Ovarian Cancer: Current Applications of Minimally Invasive Techniques

  • Giovanni Favero
  • Christhardt Köhler
  • Alexandre Silva e Silva
  • Jesus Paula Carvalho
Chapter

Abstract

In developed countries, ovarian cancer is the second most frequent cancer of the female genital tract and is certainly the most lethal [1]. The incidence and the mortality related to this neoplasm have significantly increased over the last decades, and it will certainly constitute a major healthcare problem in the near future [2]. It is estimated that 125,000 women worldwide die each year due to this condition [3]. Despite a number of screening efforts, approximately 75% of patients are diagnosed with advanced forms of the disease (advanced ovarian cancer, AOC) [4]. In fact, surgery represents the cornerstone of treatment for this condition, and diverse studies have clearly demonstrated that achievement of complete cytoreduction (no macroscopic residual tumor) has a substantial impact on survival [5, 6]. Unfortunately, due to the magnitude of disease dissemination, only in about 20–50% of the patients with AOC is primary optimal debulking surgery technically possible [4, 6, 7]. In this scenario, alternative strategies such as neoadjuvant chemotherapy (NACT), leading to higher rates of adequate resection, may be beneficial to a number of patients who are initially considered inoperable [4, 8]. The recent introduction into clinical practice of NACT for AOC, coupled with the development of modern technology and an increased number of skilled laparoscopic surgeons, has created a more favorable scenario for endoscopic debulking, at least in selected cases. However, there is currently a notorious paucity of data regarding the feasibility and oncologic safety of this new strategy.

Keywords

ovarian cancer laparoscopy surgical staging 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Giovanni Favero
    • 1
    • 2
  • Christhardt Köhler
    • 2
  • Alexandre Silva e Silva
    • 1
  • Jesus Paula Carvalho
    • 1
  1. 1.Department of GynecologyInstituto do Câncer do Estado de São Paulo – ICESP Faculdade de Medicina da Universidade de São PauloSão PauloBrazil
  2. 2.Department of Advanced Gynecologic Surgery and OncologyAsklepios Hospital HamburgHamburgGermany

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