Abstract
Clinical case. Differential diagnosis: Synucleinopathies with parkinsonism (PD, MSA, DLB). Diagnosis: Temporal profile of motor and autonomic dysfunction, brain MRI, cardiac sympathetic imaging. Main autonomic manifestations of PD: orthostatic hypotension, gastrointestinal, bladder dysfunction and sudomotor dysfunction. Symptoms management and prognosis.
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Espay AJ, LeWitt PA, Hauser RA, Merola A, Masellis M, Lang AE. Neurogenic orthostatic hypotension and supine hypertension in Parkinson’s disease and related synucleinopathies: prioritization of treatment targets. Lancet Neurol. 2016;15:954–66.
Fasano A, Visanji N, Liu LWC, Lang AE, Pfeiffer RF. Gastrointestinal dysfunction in Parkinson’s disease. Lancet Neurol. 2015;14:625–39.
Goldstein DS. Dysautonomia in Parkinson disease. Compr Physiol. 2014;4:805–26.
Vichayanrat E, Low DA, Iodice V, Stuebner E, Hagen EM, Mathias CJ. Twenty-four-hour ambulatory blood pressure and heart rate profiles in diagnosing orthostatic hypotension in Parkinson’s disease and multiple system atrophy. Eur J Neurol. 2017;24:90–7.
Sakakibara R, Tateno F, Nagao T, Yamamoto T, Uchiyama T, Yamanishi T, Yano M, Kishi M, Tsuyusaki Y, Aiba Y. Bladder function of patients with Parkinson's disease. Eur J Neurol. 2017;24:90–7.
Benarroch EE, Smithson IL, Low PA, Parisi JE. Depletion of catecholaminergic neurons of the rostral ventrolateral medulla in multiple systems atrophy with autonomic failure. Ann Neurol. 1998;43:156–63.
Benarroch EE, Schmeichel AM, Sandroni P, Low PA, Parisi JE. Involvement of vagal autonomic nuclei in multiple system atrophy and Lewy body disease. Neurology. 2006;66(3):378–83.
Ito T, Sakakibara R, Yasuda K, Yamamoto T, Uchiyama T, Liu Z, et al. Incomplete emptying and urinary retention in multiple-system atrophy: when does it occur and how do we manage it? Mov Disord. 2006;21:816–23.
Jecmenica-Lukic M, Poewe W, Tolosa E, Wenning GK. Premotor signs and symptoms of multiple system atrophy. Lancet Neurol. 2012;11:361–8.
Iodice V, Lipp A, Ahlskog JE, Sandroni P, Fealey RD, Parisi JE, Matsumoto JY, Benarroch EE, Kimpinski K, Singer W, Gehrking TL, Gehrking JA, Sletten DM, Schmeichel AM, Bower JH, Gilman S, Figueroa J, Low PA. Autopsy confirmed multiple system atrophy cases: Mayo experience and role of autonomic function tests. J Neurol Neurosurg Psychiatry. 2012;83:453–9.
Coon E, Sletten D, Suarez M, Mandrekar J, Ahlskog J, Bower J, Matsumoto J, Silber Benarroch E, Fealey R, Sandroni P, Low PA, Singer W. Clinical features and autonomic testing predict. Survival in multiple system atrophy. Brain. 2015;138:3623–31.
Coon EA, Fealey RD, Sletten DM, Mandrekar JN, Benarroch EE, Sandroni P, Low PA, Singer W. Anhidrosis in multiple system atrophy involves pre- and postganglionic sudomotor dysfunction. Mov Disord. 2017;32:397–404.
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Idiaquez, J., Benarroch, E., Nogues, M. (2018). Chronic Autonomic Failure Associated with Parkinsonism, Ataxia or Dementia. In: Idiaquez, J., Benarroch, E., Nogues, M. (eds) Evaluation and Management of Autonomic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-72251-1_7
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DOI: https://doi.org/10.1007/978-3-319-72251-1_7
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