Management of the Potential Organ Donor

  • Margaret K. M. Ellis
  • Mitchell B. Sally
  • Darren J. Malinoski


Catastrophic neurologic injury and brain death have a wide range of pathophysiologic consequences, which can affect all organ systems. By stabilizing the hemodynamic, endocrine, respiratory, inflammatory, and metabolic derangements concomitant with catastrophic brain injury, the intensivist may improve a patient’s outcome. For patients who regress to brain death, optimal critical care also improves organ donation and transplantation-related outcomes. Through standardized, goal-directed, evidence-based critical care management and multidisciplinary collaboration and coordination with organ procurement organizations, the number of potential organs for donation may be increased, and the short-term and long-term function of transplanted organs may be improved.


Brain death Organ donation Transplantation Donor management goals Deceased organ donor Critical care Organ procurement organization 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Margaret K. M. Ellis
    • 1
  • Mitchell B. Sally
    • 2
  • Darren J. Malinoski
    • 2
  1. 1.Department of Anesthesiology and Perioperative MedicineOregon Health and Science UniversityPortlandUSA
  2. 2.Department of SurgeryOregon Health & Science UniversityPortlandUSA

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