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Malignant

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The Milan System for Reporting Salivary Gland Cytopathology

Abstract

Malignant salivary gland tumors include a diverse group of primary neoplasms involving both the major and minor salivary glands. In addition, various secondary neoplasms (e.g., metastatic cutaneous squamous cell carcinoma) can also involve the salivary glands or lymph nodes within or closely associated with salivary glands. A majority of malignant tumors occur in the parotid and submandibular glands and account for most of the salivary gland fine-needle aspirations (FNA). While some low-grade salivary gland cancers overlap cytomorphologically with their benign counterparts, many of the more common primary cancers in well-sampled and prepared FNAs with adequate material for ancillary studies will exhibit features that are sufficiently distinctive to be classified as "Malignant." Once the specimen is deemed malignant, grading should be attempted since that can influence clinical management.

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Author information

Authors and Affiliations

  1. Department of Pathology, Loyola University Hospital, Maywood, IL, USA

    Swati Mehrotra, Güliz A. Barkan, Stefan E. Pambuccian & Eva M. Wojcik

  2. Pathology and Cytopathology, Jordan University Hospital, Amman, Jordan

    Mousa A. Al-Abbadi

  3. Histopathology, Microbiology and Forensic Medicine, University of Jordan – College of Medicine, Amman, Jordan

    Mousa A. Al-Abbadi

  4. Department of Anatomic and Molecular Pathology, National Laboratory of Health, Dudelange, Luxembourg

    Philippe Vielh

  5. Pathology and Laboratory Medicine, Temple University Hospital, Philadelphia, PA, USA

    He Wang

Authors
  1. Swati Mehrotra
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  2. Mousa A. Al-Abbadi
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  3. Güliz A. Barkan
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  4. Stefan E. Pambuccian
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  5. Philippe Vielh
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  6. He Wang
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  7. Eva M. Wojcik
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Corresponding author

Correspondence to Swati Mehrotra .

Editor information

Editors and Affiliations

  1. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

    William C. Faquin

  2. Unita’ Operativa Istopatologia e Citodiagnostica, Fondazione Policlinico Universitario A. Gemelli, Rome, Roma, Italy

    Esther Diana Rossi

  3. Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

    Zubair Baloch

  4. Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA

    Güliz A. Barkan

  5. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

    Maria P. Foschini

  6. Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

    Daniel F.I. Kurtycz

  7. Department of Pathology, Jewish General Hospital and McGill University, Montreal, Québec, Canada

    Marc Pusztaszeri

  8. Department of Anatomic and Molecular Pathology, National Laboratory of Health, Dudelange, Luxembourg

    Philippe Vielh

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Mehrotra, S. et al. (2018). Malignant. In: Faquin, W., et al. The Milan System for Reporting Salivary Gland Cytopathology . Springer, Cham. https://doi.org/10.1007/978-3-319-71285-7_7

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  • DOI: https://doi.org/10.1007/978-3-319-71285-7_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-71284-0

  • Online ISBN: 978-3-319-71285-7

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