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Childhood Melanoma

  • Elisabetta Fulgione
  • Elvira Moscarella
  • Graziella Babino
  • Elena De Col
  • Vincenzo Piccolo
  • Giuseppe Argenziano
Chapter

Abstract

Childhood melanoma is rare, accounting for approximately 2% of all pediatric malignant tumors. In pigmented melanoma, the multicomponent pattern is the most frequently observable dermatoscopic aspect, whereas in amelanotic melanoma a polymorphous vascular pattern, often associated with remnants of pigmentation, is usually detected. Less frequent features, but highly specific for nodular amelanotic melanoma, are the milky red globules, characterized by reddish-whitish color, irregular size, and blurred borders. Dermatoscopy, in addition to conventional and modified EFG (Elevation, Firmness, Growing) criteria, helps in detecting childhood melanoma, although histopathology is mandatory for the diagnosis.

Keywords

Childhood melanoma Pigmented melanoma Hypomelanotic/amelanotic melanoma Multicomponent pattern Polymorphous vascular pattern 

References

  1. 1.
    Ferrari A, Bono A, Baldi M et al (2005) Does melanoma behave differently in younger children than in adults? A retrospective study of 33 cases of childhood melanoma from a single institution. Pediatrics 115:649–654CrossRefPubMedGoogle Scholar
  2. 2.
    Zalaudek I, Sgambato A, Ferrara G, Argenziano G (2008) Diagnosis and management of melanocytic skin lesion in the pediatric praxis. A review of the literature. Minerva Pediatr 60:291–312PubMedGoogle Scholar
  3. 3.
    Wong MPH, Janette R, Jenine K et al (2013) Incidence of childhood and adolescent melanoma in the United States: 1073-2009. Pediatrics 131:846–854CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Lu C, Zhang J, Nagahawatte P et al (2015) The genomic landscape of childhood and adolescent melanoma. J Invest Dermatol 135:816–823CrossRefPubMedGoogle Scholar
  5. 5.
    Huynh PM, Grant-Kels JM, Grin CM (2005) Childhood melanoma: update and treatment. Int J Dermatol 44:715–723CrossRefPubMedGoogle Scholar
  6. 6.
    Richardson SK, Tannous ZS, Mihm MC Jr (2002) Congenital and infantile melanoma: review of the literature and report of an uncommon variant, pigment-synthesizing melanoma. J Am Acad Dermatol 47:77–90CrossRefPubMedGoogle Scholar
  7. 7.
    Sahin S, Levin I, Kopf AW et al (1998) Risk of melanoma in medium-sized congenital melanocytic nevi: a follow-up study. J Am Acad Dermatol 39:428–433CrossRefPubMedGoogle Scholar
  8. 8.
    Kanzler MH, Mraz-Gernhard S (2001) Primary cutaneous malignant melanoma and its precursor lesions: diagnosis and therapeutic overview. J Am Acad Dermatol 45:260–276CrossRefPubMedGoogle Scholar
  9. 9.
    Bonifazi E, Bilancia M, Berloco A et al (2001) Melanoma nel bambino da 0 a 12 anni: revisione di 289 casi di letteratura. Eur J Pediatr Dermatol 11:157–175Google Scholar
  10. 10.
    Cordoro KM, Gupta D, Frieden IJ et al (2013) Pediatric melanoma: results of a large cohort study and proposal for modified ABCD detection criteria for children. J Am Acad Dermatol 68:913–925CrossRefPubMedGoogle Scholar
  11. 11.
    Moscarella E, Piccolo V, Argenziano G et al (2013) Problematic lesions in children. Dermatol Clin 31:535–547CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Elisabetta Fulgione
    • 1
  • Elvira Moscarella
    • 1
    • 2
  • Graziella Babino
    • 1
  • Elena De Col
    • 1
  • Vincenzo Piccolo
    • 1
  • Giuseppe Argenziano
    • 1
  1. 1.Dermatology UnitUniversity of CampaniaNaplesItaly
  2. 2.Dermatology and Skin Cancer UnitArcispedale S. Maria Nuova, IRCCSReggio EmiliaItaly

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