Adjuvant Endocrine Therapy

  • Rena Shah
  • Ruth M. O’ReganEmail author
Part of the Cancer Treatment and Research book series (CTAR, volume 173)


The use of hormonal therapy in breast cancer has improved the overall outcome for patients with early-stage hormone receptor-positive disease. The choice of hormone therapy is related to multiple factors, including menopausal state, patient preference, and potential side effects. Molecular profiling has allowed therapy to be tailored for an individual patient to some extent. However, further molecular studies are needed to individualize the choice and length of adjuvant hormone therapy. Ongoing studies are evaluating the role of additional targeted therapies, such as CDK4/6 inhibitors, to further improve outcome for patients with early-stage hormone receptor-positive breast cancer.


Breast cancer Adjuvant Endocrine therapy Hormone therapy Tamoxifen Aromatase inhibitors Molecular profiling  


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.University of Wisconsin Carbone Cancer CenterMadisonUSA

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