Bacterial Allergens

  • Gómez-Gascón LidiaEmail author
  • Barbara M. Bröker
Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)


According to the hygiene hypothesis, bacterial infection as well as exposure to a complex microbial environment early in life confer protection from allergy. On the flip side of the coin, colonization and infection by certain bacterial species have been associated with an increased risk of allergy development as well as with exacerbations of allergic symptoms. Moreover, bacteria themselves and their products can become targets of allergic immune responses, eliciting the generation of specific Th2 cells and IgE. Some bacterial factors are even able to trigger allergic inflammation in animal models, suggesting that they are true allergens. This review summarizes the state of the art regarding pro-allergenic properties of bacteria.


Allergy Asthma Cystic fibrosis Bacterial allergens T-helper type 2 


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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of ImmunologyUniversity Medicine GreifswaldGreifswaldGermany

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