Diseases with Liver and Kidney Involvement

Chapter

Abstract

Many congenital and acquired diseases involve both concomitant kidney and liver disease. In these conditions the rate of disease progression is independent in each organ and a co-ordinated approach between nephrologist and hepatologist is essential for management, particularly when considering a need for combined transplantation.

Further Reading

  1. Bardet Biedl support group. Information leaflet. http://www.lmbbs.org.uk/LMBBS/file/Medical%20Booklet%202016(1).pdf.
  2. Bergmann C, Senderek J, Windelen E, Kupper F, Middeldorf I, Schneider F, Dornia C, Rudnik-Schoneborn S, Konrad M, Schmitt CP, Seeman T, Neuhaus TJ, Vester U, Kirfel J, Buttner R, Zerres K. Clinical consequences of PKHD1 mutations in 164 patients with autosomal-recessive polycystic kidney disease (ARPKD). Kidney Int. 2005;67:829–48.CrossRefGoogle Scholar
  3. Forsythe E, Sparks K, Best S, Borrows S, Hoskins B, Sabir A, Barrett T, Williams D, Mohammed S, Goldsmith D, Milford DV, Bockenhauer D, Foggensteiner L, Beales PL. Risk factors for severe renal disease in Bardet-Biedl syndrome. J Am Soc Nephrol. 2017;28:963–70.CrossRefGoogle Scholar
  4. Hulton SA. The primary hyperoxalurias: a practical approach to diagnosis and treatment. Int J Surg. 2016;36(Pt D):649–54.CrossRefGoogle Scholar
  5. Ranawaka R, Lloyd C, McKiernan PJ, Hulton SA, Sharif K, Milford DV. Combined liver and kidney transplantation in children: analysis of renal graft outcome. Pediatr Nephrol. 2016;31:1539–43.CrossRefGoogle Scholar
  6. Satir P, Pedersen LB, Christensen ST. The primary cilium at a glance. J Cell Sci. 2010;123:499–503.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NephrologyBirmingham Women’s and Children’s HospitalBirminghamUK

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