Staphylococcus spp.

  • Douglas I. Johnson
Chapter

Abstract

  • Genomics: multiple S. aureus strains have been sequenced, including methicillin-resistant and methicillin-sensitive clinical isolates and community isolates (Holden et al. 2004):
    • Staphylococcus aureus strain MRSA252 (methicillin-resistant) chromosome: 2,902,619 bp; 2671 predicted ORFs

    • Staphylococcus aureus strain MSSA476 (methicillin-sensitive) chromosome: 2,799,802 bp; 2565 predicted ORFs

    • Staphylococcus epidermidis strain ATCC 12228 chromosome: 2,499,279 bp; 2419 predicted ORFs (Zhang et al. 2003)

    • Staphylococcus saprophyticus strain ATCC 15305 chromosome: 2,516,575 bp; 2446 predicted ORFs (Kuroda et al. 2005)

  • Cell morphology:
    • Cocci: irregular “grape-like” clusters (Fig. 9.1)

  • Gram stain:
    • Gram positive

  • Growth (Ramsey et al. 2014):
    • Facultative anaerobes; catalase positive.

    • Coagulase positive (S. aureus); most other Staphylococcus spp. are coagulase negative.

    • Salt and desiccation tolerant; associated with colonization of the skin.

    • Reservoirs: ~one-third of population are carriers; predominantly found on the skin, mucous membranes in the anterior nares (nose) and the respiratory tract, the gastrointestinal tract, and on vaginal mucous membranes; occasionally found in contaminated soil and contaminated food products; antibiotic-resistant strains are often found in hospital environments.

    • Expert biofilm formers (see below).

    • At least 40 species fall into 11 taxonomic groups, many of which are associated with specific mammalian species.

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© Springer International Publishing AG 2018

Authors and Affiliations

  • Douglas I. Johnson
    • 1
  1. 1.Department of Microbiology & Molecular GeneticsUniversity of VermontBurlingtonUSA

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