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Mycoplasma spp.

  • Douglas I. Johnson
Chapter

Abstract

  • Mycoplasma pneumoniae chromosome: 816,394 bp; 677 predicted ORFs (Dandekar et al. 2000; Himmelreich et al. 1996)

  • Mycoplasma genitalium chromosome: 580,076 bp; 470 predicted ORFs (Fraser et al. 1995)

References

  1. Balish MF (2014) Mycoplasma pneumoniae, an underutilized model for bacterial cell biology. J Bacteriol 196:3675–3682CrossRefPubMedPubMedCentralGoogle Scholar
  2. Baseman JB, Morrison-Plummer J, Drouillard D, Puelo-Scheppke B, Tryon VV, Holt SC (1987) Identification of a 32-kilodalton protein of Mycoplasma pneumoniae associated with hemadsorption. Isr J Med Sci 23:474–479PubMedGoogle Scholar
  3. Bose S, Segovia JA, Somarajan SR, Chang TH, Kannan TR, Baseman JB (2014) ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity. mBio 5:e02186–e02114CrossRefPubMedPubMedCentralGoogle Scholar
  4. Dandekar T, Huynen M, Regula JT, Ueberle B, Zimmermann CU, Andrade MA (2000) Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames. Nucleic Acids Res 28:3278–3288CrossRefPubMedPubMedCentralGoogle Scholar
  5. Fraser CM, Gocayne JD, White O, Adams MD, Clayton RA, Fleischmann RD, Bult CJ, Kerlavage AR, Sutton G, Kelley JM, Fritchman RD, Weidman JF, Small KV, Sandusky M, Fuhrmann J, Nguyen D, Utterback TR, Saudek DM, Phillips CA, Merrick JM, Tomb JF, Dougherty BA, Bott KF, Hu PC, Lucier TS, Peterson SN, Smith HO, Hutchison CAR, Venter JC (1995) The minimal gene complement of Mycoplasma genitalium. Science 270:397–403CrossRefPubMedGoogle Scholar
  6. Himmelreich R, Hilbert H, Plagens H, Pirkl E, Li BC, Herrmann R (1996) Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae. Nucleic Acids Res 24:4420–4449CrossRefPubMedPubMedCentralGoogle Scholar
  7. Kannan TR, Baseman JB (2006) ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens. Proc NatI Acad Sci USA 103:6724–6729CrossRefGoogle Scholar
  8. Kannan TR, Musatovova O, Balasubramanian S, Cagle M, Jordan JL, Krunkosky TM, Davis A, Hardy RD, Baseman JB (2010) Mycoplasma pneumoniae community acquired respiratory distress syndrome toxin expression reveals growth phase and infection-dependent regulation. Mol Microbiol 76:1127–1141CrossRefPubMedPubMedCentralGoogle Scholar
  9. Krause DC (1996) Mycoplasma pneumoniae cytadherence: unravelling the tie that binds. Mol Microbiol 20:247–253CrossRefPubMedGoogle Scholar
  10. Krause DC (1998) Mycoplasma pneumoniae cytadherence: organization and assembly of the attachment organelle. Trends Microbiol 6:15–18CrossRefPubMedGoogle Scholar
  11. Lluch-Senar M, Cozzuto L, Cano J, Delgado J, Llorens-Rico V, Pereyre S, Bebear C, Serrano L (2015) Comparative “-omics” in Mycoplasma pneumoniae clinical isolates reveals key virulence factors. PLoS One 10:e0137354CrossRefPubMedPubMedCentralGoogle Scholar
  12. Nakane D, Kenri T, Matsuo L, Miyata M (2015) Systematic structural analyses of attachment organelle in Mycoplasma pneumoniae. PLoS Pathog 11:e1005299CrossRefPubMedPubMedCentralGoogle Scholar
  13. Parrott GL, Kinjo T, Fujita J (2016) A compendium for Mycoplasma pneumoniae. Front Microbiol 7:513PubMedPubMedCentralGoogle Scholar
  14. Relich RF, Balish MF (2011) Insights into the function of Mycoplasma pneumoniae protein P30 from orthologous gene replacement. Microbiology 157:2862–2870CrossRefPubMedPubMedCentralGoogle Scholar
  15. Romero-Arroyo CE, Jordan J, Peacock SJ, Willby MJ, Farmer MA, Krause DC (1999) Mycoplasma pneumoniae protein p30 is required for cytadherence and associated with proper cell development. J Bacteriol 181:1079–1087PubMedPubMedCentralGoogle Scholar
  16. Saraya T, Kurai D, Nakagaki K, Sasaki Y, Niwa S, Tsukagoshi H, Nunokawa H, Ohkuma K, Tsujimoto N, Hirao S, Wada H, Ishii H, Nakata K, Kimura H, Kozawa K, Takizawa H, Goto H (2014) Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications. Front Microbiol 5:410PubMedPubMedCentralGoogle Scholar
  17. Shimizu T (2016) Inflammation-inducing factors of Mycoplasma pneumoniae. Front Microbiol 7:414CrossRefPubMedPubMedCentralGoogle Scholar
  18. Simmons WL, Daubenspeck JM, Osborne JD, Balish MF, Waites KB, Dybvig K (2013) Type 1 and type 2 strains of Mycoplasma pneumoniae form different biofilms. Microbiology 159:737–747CrossRefPubMedPubMedCentralGoogle Scholar
  19. Su HC, Hutchison CA 3rd, Giddings MC (2007) Mapping phosphoproteins in Mycoplasma genitalium and Mycoplasma pneumoniae. BMC Microbiol 7:63CrossRefPubMedPubMedCentralGoogle Scholar
  20. Taylor-Robinson D, Jensen JS (2011) Mycoplasma genitalium: from Chrysalis to multicolored butterfly. Clin Microbiol Rev 24:498–514CrossRefPubMedPubMedCentralGoogle Scholar
  21. Unemo M, Jensen JS (2017) Antimicrobial-resistant sexually transmitted infections: gonorrhoea and Mycoplasma genitalium. Nat Rev Urol.  https://doi.org/10.1038/nrurol.2016.268
  22. Waites KB, Talkington DF (2004) Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev 17:697–728CrossRefPubMedPubMedCentralGoogle Scholar
  23. Waites KB, Xiao L, Liu Y, Balish MF, Atkinson TP (2017) Mycoplasma pneumoniae from the respiratory tract and beyond. Clin Microbiol Rev 30:747–809CrossRefPubMedGoogle Scholar
  24. Wodke JA, Alibes A, Cozzuto L, Hermoso A, Yus E, Lluch-Senar M, Serrano L, Roma G (2015) MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae. Nucleic Acids Res 43:D618–D623CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Douglas I. Johnson
    • 1
  1. 1.Department of Microbiology & Molecular GeneticsUniversity of VermontBurlingtonUSA

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