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Bacterial Pathogens and Their Virulence Factors pp 209–239Cite as

Escherichia spp.

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References

  • Ahmed SA, Awosika J, Baldwin C, Bishop-Lilly KA, Biswas B, Broomall S, Chain PS, Chertkov O, Chokoshvili O, Coyne S, Davenport K, Detter JC, Dorman W, Erkkila TH, Folster JP, Frey KG, George M, Gleasner C, Henry M, Hill KK, Hubbard K, Insalaco J, Johnson S, Kitzmiller A, Krepps M, Lo CC, Luu T, McNew LA, Minogue T, Munk CA, Osborne B, Patel M, Reitenga KG, Rosenzweig CN, Shea A, Shen X, Strockbine N, Tarr C, Teshima H, van Gieson E, Verratti K, Wolcott M, Xie G, Sozhamannan S, Gibbons HS, Threat Characterization C (2012) Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2. PLoS One 7:e48228

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Barnich N, Boudeau J, Claret L, Darfeuille-Michaud A (2003) Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn’s disease. Mol Microbiol 48:781–794

    Article  CAS  PubMed  Google Scholar 

  • Barnich N, Carvalho FA, Glasser AL, Darcha C, Jantscheff P, Allez M, Peeters H, Bommelaer G, Desreumaux P, Colombel JF, Darfeuille-Michaud A (2007) CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Investig 117:1566–1574

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012) Shiga toxins. Toxicon 60:1085–1107

    Article  CAS  PubMed  Google Scholar 

  • Bielaszewska M, Aldick T, Bauwens A, Karch H (2014) Hemolysin of enterohemorrhagic Escherichia coli: structure, transport, biological activity and putative role in virulence. Int J Med Microbiol 304:521–529

    Article  CAS  PubMed  Google Scholar 

  • Blattner FR, Plunkett G III, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y (1997) The complete genome sequence of Escherichia coli K-12. Science 277:1453–1462

    Article  CAS  PubMed  Google Scholar 

  • Boisen N, Struve C, Scheutz F, Krogfelt KA, Nataro JP (2008) New adhesin of enteroaggregative Escherichia coli related to the Afa/Dr/AAF family. Infect Immun 76:3281–3292

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Boisen N, Melton-Celsa AR, Scheutz F, O’Brien AD, Nataro JP (2015) Shiga toxin 2a and enteroaggregative Escherichia coli – a deadly combination. Gut Microbes 6:272–278

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Campellone K, Leong JM (2003) Tails of two Tirs: actin pedestal formation by enteropathogenic E. coli and enterohemorrhagic E. coli O157:H7. Curr Opin Microbiol 6:82–90

    Article  CAS  PubMed  Google Scholar 

  • Chassaing B, Rolhion N, de Vallee A, Salim SY, Prorok-Hamon M, Neut C, Campbell BJ, Soderholm JD, Hugot JP, Colombel JF, Darfeuille-Michaud A (2011) Crohn disease – associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae. J Clin Investig 121:966–975

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chaudhuri RR, Sebaihia M, Hobman JL, Webber MA, Leyton DL, Goldberg MD, Cunningham AF, Scott-Tucker A, Ferguson PR, Thomas CM, Frankel G, Tang CM, Dudley EG, Roberts IS, Rasko DA, Pallen MJ, Parkhill J, Nataro JP, Thomson NR, Henderson IR (2010) Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. PLoS One 5:e8801

    Article  PubMed  PubMed Central  Google Scholar 

  • Clements A, Young JC, Constantinou N, Frankel G (2012) Infection strategies of enteric pathogenic Escherichia coli. Gut Microbes 3:71–87

    Article  PubMed  PubMed Central  Google Scholar 

  • Cote JP, Charbonneau ME, Mourez M (2013) Glycosylation of the Escherichia coli TibA self-associating autotransporter influences the conformation and the functionality of the protein. PLoS One 8:e80739

    Article  PubMed  PubMed Central  Google Scholar 

  • Croxen MA, Finlay BB (2010) Molecular mechanisms of Escherichia coli pathogenicity. Nat Rev Microbiol 8:26–38

    CAS  PubMed  Google Scholar 

  • Croxen MA, Law RJ, Scholz R, Keeney KM, Wlodarska M, Finlay BB (2013) Recent advances in understanding enteric pathogenic Escherichia coli. Clin Microbiol Rev 26:822–880

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dale AP, Woodford N (2015) Extra-intestinal pathogenic Escherichia coli (ExPEC): disease, carriage and clones. J Infect 71:615–626

    Article  PubMed  Google Scholar 

  • Dean P, Kenny B (2009) The effector repertoire of enteropathogenic E. coli: ganging up on the host cell. Curr Opin Microbiol 12:101–109

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dudley EG, Abe C, Ghigo JM, Latour-Lambert P, Hormazabal JC, Nataro JP (2006) An IncI1 plasmid contributes to the adherence of the atypical enteroaggregative Escherichia coli strain C1096 to cultured cells and abiotic surfaces. Infect Immun 74:2102–2114

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Elsinghorst EA, Kopecko DJ (1992) Molecular cloning of epithelial cell invasion determinants from enterotoxigenic Escherichia coli. Infect Immun 60:2409–2417

    CAS  PubMed  PubMed Central  Google Scholar 

  • Elsinghorst EA, Weitz JA (1994) Epithelial cell invasion and adherence directed by the enterotoxigenic Escherichia coli tib locus is associated with a 104-kilodalton outer membrane protein. Infect Immun 62:3463–3471

    CAS  PubMed  PubMed Central  Google Scholar 

  • Estrada-Garcia T, Navarro-Garcia F (2012) Enteroaggregative Escherichia coli pathotype: a genetically heterogeneous emerging foodborne enteropathogen. FEMS Immunol Med Microbiol 66:281–298

    Article  CAS  PubMed  Google Scholar 

  • Farfan MJ, Torres AG (2012) Molecular mechanisms that mediate colonization of Shiga toxin-producing Escherichia coli strains. Infect Immun 80:903–913

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fasano A, Noriega FR, Maneval DRJ, Chanasongcram S, Russell R, Guandalini S, Levine MM (1995) Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro. J Clin Investig 95:2853–2861

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Flatau G, Lemichez E, Gauthier M, Chardin P, Paris S, Fiorentini C, Boquet P (1997) Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine. Nature 12:729–733

    Article  Google Scholar 

  • Fleckenstein JM, Hardwidge PR, Munson GP, Rasko DA, Sommerfelt H, Steinsland H (2010) Molecular mechanisms of enterotoxigenic Escherichia coli infection. Microbes Infect 12:89–98

    Article  CAS  PubMed  Google Scholar 

  • Gomes TA, Elias WP, Scaletsky IC, Guth BE, Rodrigues JF, Piazza RM, Ferreira LC, Martinez MB (2016) Diarrheagenic Escherichia coli. Braz J Microbiol 47(Suppl 1):3–30

    Article  PubMed  PubMed Central  Google Scholar 

  • Gonzales-Siles L, Sjöling AS (2016) The different ecological niches of enterotoxigenic Escherichia coli. Environ Microbiol 5:741–751

    Article  Google Scholar 

  • de Groot JC, Schluter K, Carius Y, Quedenau C, Vingadassalom D, Faix J, Weiss SM, Reichelt J, Standfuss-Gabisch C, Lesser CF, Leong JM, Heinz DW, Bussow K, Stradal TE (2011) Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli. Structure 19:1294–1306

    Article  PubMed  PubMed Central  Google Scholar 

  • Guignot J, Chaplais C, Coconnier-Polter MH, Servin AL (2007) The secreted autotransporter toxin, Sat, functions as a virulence factor in Afa/Dr diffusely adhering Escherichia coli by promoting lesions in tight junction of polarized epithelial cells. Cell Microbiol 9:204–221

    Article  CAS  PubMed  Google Scholar 

  • Henderson IR, Czeczulin J, Eslava C, Noriega F, Nataro JP (1999) Characterization of Pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun 67:5587–5596

    CAS  PubMed  PubMed Central  Google Scholar 

  • Huang SH, Wan ZS, Chen YH, Jong AY, Kim KS (2001) Further characterization of Escherichia coli brain microvascular endothelial cell invasion gene ibeA by deletion, complementation, and protein expression. J Infect Dis 183:1071–1078

    Article  CAS  PubMed  Google Scholar 

  • Hughes JM, Murad F, Chang B, Guerrant RL (1978) Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature 271:755–756

    Article  CAS  PubMed  Google Scholar 

  • Kaas RS, Friis C, Ussery DW, Aarestrup FM (2012) Estimating variation within the genes and inferring the phylogeny of 186 sequenced diverse Escherichia coli genomes. BMC Genomics 13:577–590

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kaper JB, Nataro JP, Mobley HL (2004) Pathogenic Escherichia coli. Nat Rev Microbiol 2:123–140

    Article  CAS  PubMed  Google Scholar 

  • Khan NA, Kim Y, Shin S, Kim KS (2007) FimH-mediated Escherichia coli K1 invasion of human brain microvascular endothelial cells. Cell Microbiol 9:169–178

    Article  CAS  PubMed  Google Scholar 

  • Kim KS, Itabashi H, Gemski P, Sadoff J, Warren RL, Cross AS (1992) The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat. J Clin Investig 90:897–905

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Korea CG, Ghigo JM, Beloin C (2011) The sweet connection: solving the riddle of multiple sugar-binding fimbrial adhesins in Escherichia coli: multiple E. coli fimbriae form a versatile arsenal of sugar-binding lectins potentially involved in surface-colonisation and tissue tropism. BioEssays 33:300–311

    Article  CAS  PubMed  Google Scholar 

  • Lapaquette P, Bringer MA, Darfeuille-Michaud A (2012) Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response. Cell Microbiol 14:791–807

    Article  CAS  PubMed  Google Scholar 

  • Lara-Tejero M, Galan JE (2001) CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun 69:4358–4365

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lara-Tejero M, Galán JE (2002) Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol 10:147–152

    Article  CAS  PubMed  Google Scholar 

  • Lathem WW, Grys TE, Witowski SE, Torres AG, Kaper JB, Tarr PI, Welch RA (2002) StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor. Mol Microbiol 45:277–288

    Article  CAS  PubMed  Google Scholar 

  • Law RJ, Gur-Arie L, Rosenshine I, Finlay BB (2013) In vitro and in vivo model systems for studying enteropathogenic Escherichia coli infections. Cold Spring Harb Perspect Med 3:a009977

    Article  PubMed  PubMed Central  Google Scholar 

  • Le Bouguenec C, Servin AL (2006) Diffusely adherent Escherichia coli strains expressing Afa/Dr adhesins (Afa/Dr DAEC): hitherto unrecognized pathogens. FEMS Microbiol Lett 256:185–194

    Article  PubMed  Google Scholar 

  • Lee MS, Koo S, Jeong DG, Tesh VL (2016) Shiga toxins as multi-functional proteins: induction of host cellular stress responses, role in pathogenesis and therapeutic applications. Toxins 8(77):1–23. doi:10.3390/toxins8030077

  • Liang S, Hajishengallis G (2010) Heat-labile enterotoxins as adjuvants or anti-inflammatory agents. Immunol Investig 39:449–467

    Article  CAS  Google Scholar 

  • Lindberg AA, Brown JE, Stromberg N, Westling-Ryd M, Schultz JE, Karlsson KA (1987) Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1. J Biol Chem 262:1779–1785

    CAS  PubMed  Google Scholar 

  • Lugering A, Benz I, Knochenhauer S, Ruffing M, Schmidt MA (2003) The Pix pilus adhesin of the uropathogenic Escherichia coli strain X2194 (O2 : K(−): H6) is related to Pap pili but exhibits a truncated regulatory region. Microbiology 149:1387–1397

    Article  PubMed  Google Scholar 

  • Ma Z, Jacobsen FE, Giedroc DP (2009) Metal transporters and metal sensors: how coordination chemistry controls bacterial metal homeostasis. Chem Rev 109:4644–4681

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mann EA, Saeed SA (2012) Gastrointestinal infection as a trigger for inflammatory bowel disease. Curr Opin Gastroenterol 28:24–29

    Article  CAS  PubMed  Google Scholar 

  • McWilliams BD, Torres AG (2014) Enterohemorrhagic Escherichia coli adhesins. Microbiol Spectr 2. https://doi.org/10.1128/microbiolspec.EHEC-0003-2013

  • Mellies JL, Lorenzen E (2014) Enterohemorrhagic Escherichia coli virulence gene regulation. Microbiol Spectr 2:EHEC-0004-2013

    Article  PubMed  Google Scholar 

  • Melton-Celsa AR (2014) Shiga toxin (Stx) classification, structure, and function. Microbiol Spectr 2:EHEC-0024-2013

    Google Scholar 

  • Ménard LP, Dubreuil JD (2002) Enteroaggregative Escherichia coli heat-stable enterotoxin 1 (EAST1): a new toxin with an old twist. Crit Rev Microbiol 28:43–60

    Article  PubMed  Google Scholar 

  • Miajlovic H, Smith SG (2014) Bacterial self-defence: how Escherichia coli evades serum killing. FEMS Microbiol Lett 354:1–9

    Article  CAS  PubMed  Google Scholar 

  • Mulvey MA (2002) Adhesion and entry of uropathogenic Escherichia coli. Cell Microbiol 4:257–271

    Article  CAS  PubMed  Google Scholar 

  • Nataro JP, Deng Y, Maneval DR, German AL, Martin WC, Levine MM (1992) Aggregative adherence fimbriae I of enteroaggregative Escherichia coli mediate adherence to HEp-2 cells and hemagglutination of human erythrocytes. Infect Immun 60:2297–2304

    CAS  PubMed  PubMed Central  Google Scholar 

  • Navarro-Garcia F (2014) Escherichia coli O104:H4 pathogenesis: an enteroaggregative E. coli shiga toxin-producing E. coli : explosive cocktail of high virulence. Microbiol Spectr 2. https://doi.org/10.1128/microbiolspec.EHEC-0008-2013

  • Navarro-Garcia F, Sears C, Eslava C, Cravioto A, Nataro JP (1999) Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli. Infect Immun 67:2184–2192

    CAS  PubMed  PubMed Central  Google Scholar 

  • Nesta B, Spraggon G, Alteri C, Moriel DG, Rosini R, Veggi D, Smith S, Bertoldi I, Pastorello I, Ferlenghi I, Fontana MR, Frankel G, Mobley HLT, Rappuoli R, Pizza M, Serino L, Soriani M (2012) FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. MBio 3:e00010–e00012

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Patel SK, Dotson J, Allen KP, Fleckenstein JM (2004) Identification and molecular characterization of EatA, an autotransporter protein of enterotoxigenic Escherichia coli. Infect Immun 72:1786–1794

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Perna NT, Plunkett G III, Burland V, Mau B, Glasner JD, Rose DJ, Mayhew GF, Evans PS, Gregor J, Kirkpatrick HA, Posfai G, Hackett J, Klink S, Boutin A, Shao Y, Miller L, Grotbeck EJ, Davis NW, Limk A, Dimalantak ET, Potamousis KD, Apodaca J, Anantharaman TS, Lin J, Yen G, Schwartz DC, WelchI RA, Blattner FR (2001) Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature 409:529–533

    Article  CAS  PubMed  Google Scholar 

  • Porcheron G, Garenaux A, Proulx J, Sabri M, Dozois CM (2013) Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence. Front Cell Infect Microbiol 3:90

    Article  PubMed  PubMed Central  Google Scholar 

  • Prasadarao NV (2002) Identification of Escherichia coli outer membrane protein A receptor on human brain microvascular endothelial cells. Infect Immun 70:4556–4563

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ristow LC, Welch RA (2016) Hemolysin of uropathogenic Escherichia coli: a cloak or a dagger? BBA 1858:538–545

    Article  CAS  PubMed  Google Scholar 

  • Rolhion N, Barnich N, Claret L, Darfeuille-Michaud A (2005) Strong decrease in invasive ability and outer membrane vesicle release in Crohn’s disease-associated adherent-invasive Escherichia coli strain LF82 with the yfgL gene deleted. J Bacteriol 187:2286–2296

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rolhion N, Barnich N, Bringer MA, Glasser AL, Ranc J, Hebuterne X, Hofman P, Darfeuille-Michaud A (2010) Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion. Gut 59:1355–1362

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Roy K, Hilliard GM, Hamilton DJ, Luo J, Ostmann MM, Fleckenstein JM (2009) Enterotoxigenic Escherichia coli EtpA mediates adhesion between flagella and host cells. Nature 457:594–598

    Article  CAS  PubMed  Google Scholar 

  • Schmidt MA (2010) LEEways: tales of EPEC, ATEC and EHEC. Cell Microbiol 12:1544–1552

    Article  CAS  PubMed  Google Scholar 

  • Schmidt G, Sehr P, Wilm M, Selzer J, Mann M, Aktories K (1997) Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1. Nature 12:725–729

    Article  Google Scholar 

  • Servin AL (2005) Pathogenesis of Afa/Dr diffusely adhering Escherichia coli. Clin Microbiol Rev 18:264–292

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sharma G, Sharma S, Sharma P, Chandola D, Dang S, Gupta S, Gabrani R (2016) Escherichia coli biofilm: development and therapeutic strategies. J Appl Microbiol 121:309–319

    Article  CAS  PubMed  Google Scholar 

  • Sheikh J, Czeczulin JR, Harrington S, Hicks S, Henderson IR, Le Bouguénec C, Gounon P, Phillips A, Nataro JP (2002) A novel dispersin protein in enteroaggregative Escherichia coli. J Clin Investig 110:1329–1337

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Singh AP, Aijaz S (2016) Enteropathogenic E. coli: breaking the intestinal tight junction barrier. F1000Res 4:231

    Article  PubMed Central  Google Scholar 

  • Snyder GA, Cirl C, Jiang J, Chen K, Waldhuber A, Smith P, Römmler F, Snyder N, Fresquez T, Dürr S, Tjandra N, Miethke T, Xiao TS (2013) Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc NatI Acad Sci USA 110:6985–6990

    Article  CAS  Google Scholar 

  • Spangler BD (1992) Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 56:622–647

    CAS  PubMed  PubMed Central  Google Scholar 

  • Spurbeck RR, Stapleton AE, Johnson JR, Walk ST, Hooton TM, Mobley HL (2011) Fimbrial profiles predict virulence of uropathogenic Escherichia coli strains: contribution of ygi and yad fimbriae. Infect Immun 79:4753–4763

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Turner SM, Scott-Tucker A, Cooper LM, Henderson IR (2006) Weapons of mass destruction: virulence factors of the global killer enterotoxigenic Escherichia coli. FEMS Microbiol Lett 263:10–20

    Article  CAS  PubMed  Google Scholar 

  • Vila J, Sáez-López E, Johnson JR, Römling U, Dobrindt U, Cantón R, Giske CG, Naas T, Carattoli A, Martínez-Medina M, Bosch J, Retamar P, Rodríguez-Baño J, Baquero F, Soto SM, Gerdes K (2016) Escherichia coli: an old friend with new tidings. FEMS Microbiol Rev 40:437–463

    Article  CAS  PubMed  Google Scholar 

  • Weiglmeier PR, Rosch P, Berkner H (2010) Cure and curse: E. coli heat-stable enterotoxin and its receptor guanylyl cyclase C. Toxins 2:2213–2229

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wiles TJ, Kulesus RR, Mulvey MA (2008) Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp Mol Pathol 85:11–19

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wong AR, Pearson JS, Bright MD, Munera D, Robinson KS, Lee SF, Frankel G, Hartland EL (2011) Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements. Mol Microbiol 80:1420–1438

    Article  CAS  PubMed  Google Scholar 

  • Zhou M, Yang Y, Chen P, Hu H, Hardwidge PR, Zhu G (2015) More than a locomotive organelle: flagella in Escherichia coli. Appl Microbiol Biotechnol 99:8883–8890

    Article  CAS  PubMed  Google Scholar 

  • Zhuang X, Chen Z, He C, Wang L, Zhou R, Yan D, Ge B (2017) Modulation of host signaling in the inflammatory response by enteropathogenic Escherichia coli virulence proteins. Cell Mol Immunol 14:237–244

    Article  CAS  PubMed  Google Scholar 

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    Douglas I. Johnson

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Johnson, D.I. (2018). Escherichia spp.. In: Bacterial Pathogens and Their Virulence Factors. Springer, Cham. https://doi.org/10.1007/978-3-319-67651-7_15

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