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Key Roles of Reactive Oxygen and Nitrogen Species

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Comprehensive Clinical Plasma Medicine

Abstract

Reactive oxygen and nitrogen species (RONS) are formed in biologically significant quantities whenever cold atmospheric pressure plasma is established in or near air. RONS enter adjacent aqueous liquid solutions readily and can strongly affect cells and tissue, mainly through their influence on redox (‘oxidation-reduction’) biological processes. Understanding and controlling these interactions is essential to plasma biomedical interactions. Plasma biomedicine is therefore significantly based on the complex and multiple properties of free radicals and other reactive species in a biological context. This chapter briefly summarizes some of the key emerging concepts of RONS in plasma biomedicine as well as some of the classic references regarding the roles of RONS in aerobic biology and medicine.

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Author information

Authors and Affiliations

  1. Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA

    David B. Graves

  2. Institute of Virology, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany

    Georg Bauer

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  1. David B. Graves
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  2. Georg Bauer
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Corresponding author

Correspondence to David B. Graves .

Editor information

Editors and Affiliations

  1. University Medicine Greifswald, Department of Oral and Maxillofacial Surgery/Plastic Surgery, Greifswald, Germany

    Hans-Robert Metelmann

  2. Leibniz Institute for Plasma Science and Technology (INP Greifswald) and University Medicine Greifswald Institute for Hygiene and Environmental Medicine, Greifswald, Germany

    Thomas von Woedtke

  3. Leibniz Institute for Plasma Science and Technology (INP Greifswald), Greifswald, Germany

    Klaus-Dieter Weltmann

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Graves, D.B., Bauer, G. (2018). Key Roles of Reactive Oxygen and Nitrogen Species. In: Metelmann, HR., von Woedtke, T., Weltmann, KD. (eds) Comprehensive Clinical Plasma Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-67627-2_4

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  • DOI: https://doi.org/10.1007/978-3-319-67627-2_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-67626-5

  • Online ISBN: 978-3-319-67627-2

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