Perspectives in General Surgery
Non-thermal plasma (NTP) offers promising opportunities to advance and refine surgical practice. The combination of stimulating tissue proliferation and decreasing bacterial load predestines NTP as add-on tool in wound treatment. Additionally, plasma-based modification of foreign materials, such as, vascular grafts or osteosynthesis materials improves their biocompatibility. Surgery in oncology is another auspicious field of application. Micrometastasis in the margins of excised tumors often cause tumor relapse. Due to selective induction of apoptosis in tumor cells, NTP treatment of wound margins after surgical bulk removal offers great potential minimize disease recurrence and improve patients’ outcome. However, compatibility with the special setting in an operating theatre is an issue not addressed yet with most plasma sources.
KeywordsNew surgical approaches Non-thermal plasma Tumor therapy Wound healing
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