Abstract
In the present study we examined the effects of working memory training on cognitive flexibility in humans. Forty healthy male participants were divided into three groups (matched for demographic variables, schizotypy, impulsivity and baseline cognitive flexibility): a) fully adapted group (participants were fully trained with an executive working memory task for six consecutive days); b) partially adapted group (participants were partially trained with an executive working memory task for six consecutive days) and c) control group (participants did not receive cognitive training). Following training, participants were examined with a second cognitive flexibility task. We found that the fully adapted group had improved cognitive flexibility (they made fewer errors and needed fewer attempts to complete the test) compared with both the partially adapted (all p values <0.005) and the control (all p values <0.05) groups, who did not differ between each other (all p values >0.2). These findings could have significant implications in the development of therapeutic approaches for the improvement of cognitive deficits in neuropsychiatric disorders.
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References
Cañas, J.J., Quesada, J.F., AntolÃ, A., Fajardo, I.: Cognitive flexibility and adaptability to environmental changes in dynamic complex problem-solving tasks. Ergonomics 46(5), 482–501 (2007)
Moore, A., Malinowski, P.: Meditation, mindfulness and cognitive flexibility. Consciousness and Cognition 18, 176–186 (2009)
Boyle, P.A., Malloy, P.F., Salloway, S., Cahn-Weiner, D.A., Cohen, R., Cummings, J.L.: Executive Dysfunction and Apathy Predict Functional Impairment in Alzheimer Disease. The American Journal of Geriatric Psychiatry 11, 214–221 (2003)
Zgaljardic, D.J., Borodbc, J.C., Foldibd, N.S., Mattisa, P.J., Gordone, M.F., Feigina, A., Eidelberga, D.: An Examination of Executive Dysfunction Associated with Frontostriatal Circuitry in Parkinson’s disease. Journal of Clinical and Experimental Neuropsychology 28, 1127–1144 (2006)
Paul, S.M., Mytelka, D.S., Dunwiddie, C.T., Persinger, C.C., Munos, B.H., Lindborg, S.R., Schacht, A.L.: How to improve R&D productivity: the pharmaceutical industry’s grand challenge. Nature Reviews Drug Discovery 9, 203–214 (2010)
Baddeley, A.: Working Memory. Clarendon Press, Oxford (1986)
Honey, G.D., Fu, C.H., Kim, J., Brammer, M.J., Croudace, T.J., Suckling, J., Pich, E.M., Williams, S.C., Bullmore, E.T.: Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging data. NeuroImage 17, 573–582 (2002)
Jonides, J.: Working memory and thinking. In: Smith, E., Osherson, D. (eds.) Invitation to Cognitive Science: Thinking, pp. 215–265. MIT Press, Cambridge (2002)
Gur, R.E., Calkins, M.E., Gur, R.C., Horan, W.P., Nuechterlein, K.H., Seidman, L.J., Horan, W.P., Nuechterlein, K.H., Seidman, L.J., Stone, W.S.: The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes (2007)
Dajani, D.R., Uddin, L.Q.: Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience. Trends in Neurosciences 38, 571–578 (2015)
Jolles, D.D., van Buchem, M.A., Crone, E.A., Rombouts, S.A.R.B.: Functional brain connectivity at rest changes after working memory training. Human Brain Mapping 34(2), 396–406 (2013)
Dresler, M., Shirer, W.R., Konrad, B.N., Müller, N.C.J., Wagner, I.C., Fernández, G., et al.: Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron 93(5), 1227–1235 (2017)
Olesen, P.J., Westerberg, H., Klingberg, T.: Increased prefrontal and parietal activity after training of working memory. Nature Neuroscience 7, 75–79 (2004)
Morrison, A.B., Chein, J.M.: Does working memory training work? The promise and challenges of enhancing cognition by training working memory. Psychonomic Bulletin & Review 18, 46–60 (2011)
Klingberg, T., Fernell, E., Olesen, P.J., Johnson, M., Gustafsson, P., Dahlstrom, K., Gillberg, C.G., Forssberg, H., Westerberg, H.: Computerized Training of Working Memory in Children With ADHD-A Randomized, Controlled Trial. Journal of the American Academy of Child & Adolescent Psychiatry 44, 177–186, 920 (2005)
Buschkuehl, M., Jaeggi, S.M., Jonides, J.: Neuronal effects following working memory training. Developmental Cognitive Neuroscience 2, 167–179 (2012)
Verghese, J., Mahoney, J., Ambrose, A.F., Wang, C., Holtzer, R.: Effect of cognitive remediation on gait in sedentary seniors. Journal of Gerontology. A Biological Sciences Medical Sciences 65(A), 1338–1343 (2010)
Papp, K.V., Walsh, S.J., Snyder, P.J.: Immediate and delayed effects of cognitive interventions in healthy elderly: a review of current literature and future directions. Alzheimers Dementia 5, 50–60 (2009)
Shatil, E.: Does combined cognitive training and physical activity training enhance cognitive abilities more than either alone? A four-condition randomized controlled trial among healthy older adults. Frontiers in Aging Neuroscience 5, 1–12 (2013)
Persson, J., Reuter-Lorenz, P.: Gaining control: Training executive function and far transfer of the ability to resolve interference. Psychological Science 19(9), 881–888 (2008)
Klingberg, T.: Training and plasticity of working memory. Trends in cognitive Sciences 14, 317–324 (2010)
Dahlin, E., Neely, A.S., Larsson, A., Bäckman, L., Nyberg, L.: Transfer of Learning After Updating Training Mediated by the Striatum. Science 320, 1510–1512 (2008)
Curtis, E.C., D’Esposito, M.: Persistent activity in the prefrontal cortex during working memory. Trends in Cognitive Sciences 7, 415–423 (2003)
Kim, C., Johnson, N.F., Cilles, S.E., Gold, B.T.: Common and Distinct Mechanisms of Cognitive Flexibility in Prefrontal Cortex. The Journal of Neuroscience 31, 4771–4779 (2011)
Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Dunbar, G.C.: The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry 59, 22–33 (1998)
Wechsler, D.: Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). NCS Pearson Inc., San Antonio (2008)
Raven, J., Raven, J.C., Court, J.H.: Manual for Raven’s Progressive Matrices and Vocabulary Scales. Section 1: General Overview. Harcourt Assessment, San Antonio (2003)
Nelson, H.E.: A modified card sorting test sensitive to frontal lobe defects. Cortex 12(4), 313–324 (1976)
Milner, B.: Effects of different brain lesions on card sorting. Archives of Neurology 9(1), 90–100 (1963)
Fray, P.J., Robbins, T.W.: Cantab battery: Proposed utility in neurotoxicology. Neurotoxicology and Teratology 18(4), 499–504 (1996)
Robbins, T.W., James, M., Owen, A.M., Sahakian, B.J., Lawrence, A.D., McInnes, L., Rabbitt, P.M.A.: A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging. Journal of the International Neuropsychological Society 4(5), 474–490 (1998)
Tsaousis, I., Zouraraki, C., Karamaouna, P., Karagiannopoulou, L., Giakoumaki, S.G.: The validity of the Schizotypal Personality Questionnaire in a Greek sample: tests of measurement invariance and latent mean differences. Comprehensive Psychiatry 62, 51–62 (2015)
Raine, A.: The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. Schizophrenia Bulletin 17(4), 555–564 (1991)
Patton, J.H., Stanford, M.S., Barratt, E.S.: Factor structure of the Barratt impulsiveness scale. Journal of Clinical Psychology 51(6), 768–774 (1995)
Takeuchi, H., Taki, Y., Kawashima, R.: Effects of Working Memory Training on Cognitive Functions and Neural Systems. Reviews in the Neurosciences 21, 427–449 (2010)
Miyake, A., Friedman, N.P., Emerson, M.J., Wizki, A.H., Howerter, A., Wager, T.D.: The Unity and Diversity of Executive Functions and Their Contributions to Complex ‘‘Frontal Lobe’’ Tasks: A Latent Variable Analysis. Cognitive Psychology 41, 49–100 (2000)
Schwaighofer, M., Fischer, F., Bühner, M.: Does Working Memory Training Transfer? A Meta-Analysis Including Training Conditions as Moderators. Educational Psychologist 50, 138–166 (2015)
Dresler, M., Shirer, W.R., Konrad, B.N., Müller, N.C.J., Wagner, I.C., Fernández, G., Czisch, M., Greicius, M.D.: Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron 93, 1227–1235 (2017)
Stokes, M.G., Kusunoki, M., Sigala, N., Nili, H., Gaffan, D., Duncan, J.: Dynamic Coding for Cognitive Control in Prefrontal Cortex. Neuron 78, 364–375 (2013)
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Stavroulaki, V., Kazantzaki, E., Bitsios, P., Sidiropoulou, K., Giakoumaki, S.G. (2017). The Effects of Working Memory Training on Cognitive Flexibility in Man. In: Frasson, C., Kostopoulos, G. (eds) Brain Function Assessment in Learning. BFAL 2017. Lecture Notes in Computer Science(), vol 10512. Springer, Cham. https://doi.org/10.1007/978-3-319-67615-9_7
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DOI: https://doi.org/10.1007/978-3-319-67615-9_7
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