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The Effects of Working Memory Training on Cognitive Flexibility in Man

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Brain Function Assessment in Learning (BFAL 2017)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 10512))

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Abstract

In the present study we examined the effects of working memory training on cognitive flexibility in humans. Forty healthy male participants were divided into three groups (matched for demographic variables, schizotypy, impulsivity and baseline cognitive flexibility): a) fully adapted group (participants were fully trained with an executive working memory task for six consecutive days); b) partially adapted group (participants were partially trained with an executive working memory task for six consecutive days) and c) control group (participants did not receive cognitive training). Following training, participants were examined with a second cognitive flexibility task. We found that the fully adapted group had improved cognitive flexibility (they made fewer errors and needed fewer attempts to complete the test) compared with both the partially adapted (all p values <0.005) and the control (all p values <0.05) groups, who did not differ between each other (all p values >0.2). These findings could have significant implications in the development of therapeutic approaches for the improvement of cognitive deficits in neuropsychiatric disorders.

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References

  1. Cañas, J.J., Quesada, J.F., Antolí, A., Fajardo, I.: Cognitive flexibility and adaptability to environmental changes in dynamic complex problem-solving tasks. Ergonomics 46(5), 482–501 (2007)

    Article  Google Scholar 

  2. Moore, A., Malinowski, P.: Meditation, mindfulness and cognitive flexibility. Consciousness and Cognition 18, 176–186 (2009)

    Article  Google Scholar 

  3. Boyle, P.A., Malloy, P.F., Salloway, S., Cahn-Weiner, D.A., Cohen, R., Cummings, J.L.: Executive Dysfunction and Apathy Predict Functional Impairment in Alzheimer Disease. The American Journal of Geriatric Psychiatry 11, 214–221 (2003)

    Article  Google Scholar 

  4. Zgaljardic, D.J., Borodbc, J.C., Foldibd, N.S., Mattisa, P.J., Gordone, M.F., Feigina, A., Eidelberga, D.: An Examination of Executive Dysfunction Associated with Frontostriatal Circuitry in Parkinson’s disease. Journal of Clinical and Experimental Neuropsychology 28, 1127–1144 (2006)

    Article  Google Scholar 

  5. Paul, S.M., Mytelka, D.S., Dunwiddie, C.T., Persinger, C.C., Munos, B.H., Lindborg, S.R., Schacht, A.L.: How to improve R&D productivity: the pharmaceutical industry’s grand challenge. Nature Reviews Drug Discovery 9, 203–214 (2010)

    Google Scholar 

  6. Baddeley, A.: Working Memory. Clarendon Press, Oxford (1986)

    Google Scholar 

  7. Honey, G.D., Fu, C.H., Kim, J., Brammer, M.J., Croudace, T.J., Suckling, J., Pich, E.M., Williams, S.C., Bullmore, E.T.: Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging data. NeuroImage 17, 573–582 (2002)

    Article  Google Scholar 

  8. Jonides, J.: Working memory and thinking. In: Smith, E., Osherson, D. (eds.) Invitation to Cognitive Science: Thinking, pp. 215–265. MIT Press, Cambridge (2002)

    Google Scholar 

  9. Gur, R.E., Calkins, M.E., Gur, R.C., Horan, W.P., Nuechterlein, K.H., Seidman, L.J., Horan, W.P., Nuechterlein, K.H., Seidman, L.J., Stone, W.S.: The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes (2007)

    Google Scholar 

  10. Dajani, D.R., Uddin, L.Q.: Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience. Trends in Neurosciences 38, 571–578 (2015)

    Article  Google Scholar 

  11. Jolles, D.D., van Buchem, M.A., Crone, E.A., Rombouts, S.A.R.B.: Functional brain connectivity at rest changes after working memory training. Human Brain Mapping 34(2), 396–406 (2013)

    Article  Google Scholar 

  12. Dresler, M., Shirer, W.R., Konrad, B.N., Müller, N.C.J., Wagner, I.C., Fernández, G., et al.: Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron 93(5), 1227–1235 (2017)

    Article  Google Scholar 

  13. Olesen, P.J., Westerberg, H., Klingberg, T.: Increased prefrontal and parietal activity after training of working memory. Nature Neuroscience 7, 75–79 (2004)

    Article  Google Scholar 

  14. Morrison, A.B., Chein, J.M.: Does working memory training work? The promise and challenges of enhancing cognition by training working memory. Psychonomic Bulletin & Review 18, 46–60 (2011)

    Article  Google Scholar 

  15. Klingberg, T., Fernell, E., Olesen, P.J., Johnson, M., Gustafsson, P., Dahlstrom, K., Gillberg, C.G., Forssberg, H., Westerberg, H.: Computerized Training of Working Memory in Children With ADHD-A Randomized, Controlled Trial. Journal of the American Academy of Child & Adolescent Psychiatry 44, 177–186, 920 (2005)

    Google Scholar 

  16. Buschkuehl, M., Jaeggi, S.M., Jonides, J.: Neuronal effects following working memory training. Developmental Cognitive Neuroscience 2, 167–179 (2012)

    Article  Google Scholar 

  17. Verghese, J., Mahoney, J., Ambrose, A.F., Wang, C., Holtzer, R.: Effect of cognitive remediation on gait in sedentary seniors. Journal of Gerontology. A Biological Sciences Medical Sciences 65(A), 1338–1343 (2010)

    Google Scholar 

  18. Papp, K.V., Walsh, S.J., Snyder, P.J.: Immediate and delayed effects of cognitive interventions in healthy elderly: a review of current literature and future directions. Alzheimers Dementia 5, 50–60 (2009)

    Article  Google Scholar 

  19. Shatil, E.: Does combined cognitive training and physical activity training enhance cognitive abilities more than either alone? A four-condition randomized controlled trial among healthy older adults. Frontiers in Aging Neuroscience 5, 1–12 (2013)

    Article  Google Scholar 

  20. Persson, J., Reuter-Lorenz, P.: Gaining control: Training executive function and far transfer of the ability to resolve interference. Psychological Science 19(9), 881–888 (2008)

    Article  Google Scholar 

  21. Klingberg, T.: Training and plasticity of working memory. Trends in cognitive Sciences 14, 317–324 (2010)

    Article  Google Scholar 

  22. Dahlin, E., Neely, A.S., Larsson, A., Bäckman, L., Nyberg, L.: Transfer of Learning After Updating Training Mediated by the Striatum. Science 320, 1510–1512 (2008)

    Article  Google Scholar 

  23. Curtis, E.C., D’Esposito, M.: Persistent activity in the prefrontal cortex during working memory. Trends in Cognitive Sciences 7, 415–423 (2003)

    Article  Google Scholar 

  24. Kim, C., Johnson, N.F., Cilles, S.E., Gold, B.T.: Common and Distinct Mechanisms of Cognitive Flexibility in Prefrontal Cortex. The Journal of Neuroscience 31, 4771–4779 (2011)

    Article  Google Scholar 

  25. Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Dunbar, G.C.: The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry 59, 22–33 (1998)

    Google Scholar 

  26. Wechsler, D.: Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). NCS Pearson Inc., San Antonio (2008)

    Google Scholar 

  27. Raven, J., Raven, J.C., Court, J.H.: Manual for Raven’s Progressive Matrices and Vocabulary Scales. Section 1: General Overview. Harcourt Assessment, San Antonio (2003)

    Google Scholar 

  28. Nelson, H.E.: A modified card sorting test sensitive to frontal lobe defects. Cortex 12(4), 313–324 (1976)

    Article  Google Scholar 

  29. Milner, B.: Effects of different brain lesions on card sorting. Archives of Neurology 9(1), 90–100 (1963)

    Article  Google Scholar 

  30. Fray, P.J., Robbins, T.W.: Cantab battery: Proposed utility in neurotoxicology. Neurotoxicology and Teratology 18(4), 499–504 (1996)

    Article  Google Scholar 

  31. Robbins, T.W., James, M., Owen, A.M., Sahakian, B.J., Lawrence, A.D., McInnes, L., Rabbitt, P.M.A.: A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging. Journal of the International Neuropsychological Society 4(5), 474–490 (1998)

    Article  Google Scholar 

  32. Tsaousis, I., Zouraraki, C., Karamaouna, P., Karagiannopoulou, L., Giakoumaki, S.G.: The validity of the Schizotypal Personality Questionnaire in a Greek sample: tests of measurement invariance and latent mean differences. Comprehensive Psychiatry 62, 51–62 (2015)

    Article  Google Scholar 

  33. Raine, A.: The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. Schizophrenia Bulletin 17(4), 555–564 (1991)

    Article  Google Scholar 

  34. Patton, J.H., Stanford, M.S., Barratt, E.S.: Factor structure of the Barratt impulsiveness scale. Journal of Clinical Psychology 51(6), 768–774 (1995)

    Article  Google Scholar 

  35. Takeuchi, H., Taki, Y., Kawashima, R.: Effects of Working Memory Training on Cognitive Functions and Neural Systems. Reviews in the Neurosciences 21, 427–449 (2010)

    Article  Google Scholar 

  36. Miyake, A., Friedman, N.P., Emerson, M.J., Wizki, A.H., Howerter, A., Wager, T.D.: The Unity and Diversity of Executive Functions and Their Contributions to Complex ‘‘Frontal Lobe’’ Tasks: A Latent Variable Analysis. Cognitive Psychology 41, 49–100 (2000)

    Article  Google Scholar 

  37. Schwaighofer, M., Fischer, F., Bühner, M.: Does Working Memory Training Transfer? A Meta-Analysis Including Training Conditions as Moderators. Educational Psychologist 50, 138–166 (2015)

    Article  Google Scholar 

  38. Dresler, M., Shirer, W.R., Konrad, B.N., Müller, N.C.J., Wagner, I.C., Fernández, G., Czisch, M., Greicius, M.D.: Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron 93, 1227–1235 (2017)

    Article  Google Scholar 

  39. Stokes, M.G., Kusunoki, M., Sigala, N., Nili, H., Gaffan, D., Duncan, J.: Dynamic Coding for Cognitive Control in Prefrontal Cortex. Neuron 78, 364–375 (2013)

    Article  Google Scholar 

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Correspondence to Stella G. Giakoumaki .

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Stavroulaki, V., Kazantzaki, E., Bitsios, P., Sidiropoulou, K., Giakoumaki, S.G. (2017). The Effects of Working Memory Training on Cognitive Flexibility in Man. In: Frasson, C., Kostopoulos, G. (eds) Brain Function Assessment in Learning. BFAL 2017. Lecture Notes in Computer Science(), vol 10512. Springer, Cham. https://doi.org/10.1007/978-3-319-67615-9_7

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  • DOI: https://doi.org/10.1007/978-3-319-67615-9_7

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