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Natural Antimicrobial Agents pp 289–327Cite as

Natural Products and Hepatitis C Virus

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Part of the book series: Sustainable Development and Biodiversity ((SDEB,volume 19))

Abstract

Hepatitis C is a major health problem worldwide. For a long time, it has not been possible to grow in cell culture the virus responsible for this disease. This impeded the development of efficient antiviral treatments. In the past decade, the establishment of a hepatitis C virus (HCV) cell culture model led to numerous studies aiming at finding chemical compounds with anti-HCV activity. A number of natural compounds were isolated and identified from plants, which inhibit various steps of the HCV life cycle. A review of the current knowledge on plant-derived natural compounds with anti-HCV activities is presented in this chapter.

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Acknowledgements

We thank Jean Dubuisson for his support and for useful discussions and Sophana Ung for preparing the illustrations. HCV research conducted by the authors is supported by “Université de Lille” and “Centre National de la Recherche Scientifique” (CNRS) via a PEPS project.

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  1. Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL Center for Infection and Immunity of Lille, 59000, Lille, France

    Karin Séron, Marie-Emmanuelle Sahuc & Yves Rouillé

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  1. Karin Séron
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Correspondence to Karin Séron .

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  1. Faculty of Pharmaceutical Sciences, Institute of Vine and Wine Sciences, University of Bordeaux, Villenave d’Ornon, France

    Jean-Michel Mérillon

  2. Faculty of Pharmaceutical Sciences, Institute of Research in Agro-food and Biotechnology Charles Viollette, University of Lille, Lille, France

    Céline Riviere

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Séron, K., Sahuc, ME., Rouillé, Y. (2018). Natural Products and Hepatitis C Virus. In: Mérillon, JM., Riviere, C. (eds) Natural Antimicrobial Agents. Sustainable Development and Biodiversity, vol 19. Springer, Cham. https://doi.org/10.1007/978-3-319-67045-4_12

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