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Manufacturing of Biologics


Biologics have brought a new dimension to the treatment of chronic diseases. As compared to small molecules, biologics are created in living cells and thus the manufacturing of biologics is a complex process. This chapter discusses the multistep approach used to manufacture biotechnology-derived biologics. The chapter also discusses biosimilars and the complexity of their development and manufacturing along with highlighting the differences between two often-confused terms—biosimilarity and comparability.

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Correspondence to Primal Kaur MD, MBA .

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Nathan, J.J., Ramchandani, M., Kaur, P. (2018). Manufacturing of Biologics. In: Yamauchi, P. (eds) Biologic and Systemic Agents in Dermatology. Springer, Cham.

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