An Approach for Needle Based Optical Coherence Elastography Measurements
- 7.1k Downloads
While navigation and interventional guidance are typically based on image data, the images do not necessarily reflect mechanical tissue properties. Optical coherence elastography (OCE) presents a modality with high sensitivity and very high spatial and temporal resolution. However, OCE has a limited field of view of only 2–5 mm depth. We present a side-facing needle probe to image externally induced shear waves from within soft tissue. A first method of quantitative needle-based OCE is provided. Using a time of flight setup, we establish the shear wave velocity and estimate the tissue elasticity. For comparison, an external scan head is used for imaging. Results for four different phantoms indicate a good agreement between the shear wave velocities estimated from the needle probe at different depths and the scan head. The velocities ranging from 0.9–3.4 m/s agree with the expected values, illustrating that tissue elasticity estimates from within needle probes are feasible.
KeywordsOptical coherence elastography Interventional imaging
- 1.Liang, D., et al.: Simulation and experiment of soft-tissue deformation in prostate brachytherapy. J. Eng. Med. 230, 6 (2016)Google Scholar
- 2.Song, S., et al.: Optical coherence elastography based on high speed imaging of single-shot laser-induced acoustic waves at 16 kHz frame rate. Proc. SPIE 9697, 10 (2016)Google Scholar
- 6.Kennedy, K.M., et al.: Needle optical coherence elastography for the measurement of microscale mechanical contrast deep within human breast tissues. J. Biomed. Opt. 18, 12 (2013)Google Scholar