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Composition of Protein–Protein Interfaces

  • L. Ridgway Scott
  • Ariel Fernández
Chapter
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Abstract

We now turn to a key question: what factors are most influential in protein-ligand binding? We review attempts to answer this question both to give a sense of the historical development and also to emphasize key aspects of the datamining techniques used.

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Departments of Computer Science and Mathematics, Institute for Biophysical Dynamics, Computation InstituteUniversity of ChicagoChicagoUSA
  2. 2.Collegium Basilea, Institute for Advanced StudyBaselSwitzerland
  3. 3.IAM - Argentine Institute of Mathematics, INQUISUR - Chemistry InstituteCONICET - National Research CouncilBuenos AiresArgentina

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