Abstract
Computed tomography (CT) provides quantitative assessment of tissue properties by a unique linear relationship between signal and CT contrast agents. Clinically, CT is widely used in the acute setting but also for chronic conditions. High radiation dose and the potential for contrast-induced acute kidney injury are the two major challenges for CT. This chapter briefly summarizes the clinical use of CT and presents the physical and technical basis of CT data acquisition and image reconstruction.
References
Hounsfield GN. Computerized transverse axial scanning (tomography). 1. Description of system. Br J Radiol. 1973;46:1016–22.
Ambrose J, Hounsfield G. Computerized transverse axial tomography. Br J Radiol. 1973;46:148–9.
Cormack AM. Nobel award address. Early two-dimensional reconstruction and recent topics stemming from it. Med Phys. 1980;7:277–82.
Cormack AM. Representation of a function by its line integrals, with some radiological applications. J Appl Phys. 1964;35:2908–13.
Kalender WA, Seissler W, Klotz E, Vock P. Spiral volumetric CT with single-breath-hold technique, continuous transport, and continuous scanner rotation. Radiology. 1990;176:181–3.
Schuetz GM, Schlattmann P, Dewey M. Avoiding overestimation of clinical performance by applying a 3x2 table with an intention-to-diagnose approach: an exemplary meta-analytical evaluation of coronary CT angiography studies. BMJ. 2012;345:e6717.
Schuetz GM, Zacharopoulou NM, Schlattmann P, Dewey M. Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging. Ann Intern Med. 2010;152:167–77.
Kachelriess M, Kalender WA. Electrocardiogram-correlated image reconstruction from subsecond spiral computed tomography scans of the heart. Med Phys. 1998;25:2417–31.
Dewey M, Rief M, Martus P, et al. Evaluation of computed tomography in patients with atypical angina or chest pain clinically referred for invasive coronary angiography: randomised controlled trial. BMJ. 2016;355:i5441.
EC. Medical radiation exposure of the European population; 2014.
Kalender W. CT: John Wiley & Sons; 2011.
NICE. CG 95 2016.
Moschovitis A, Cook S, Meier B. Percutaneous coronary interventions in Europe in 2006. EuroIntervention. 2010;6:189–94.
Williams MC, Hunter A, Shah AS, et al. Use of coronary computed tomographic angiography to guide management of patients with coronary disease. J Am Coll Cardiol. 2016;67:1759–68.
Field JK, Devaraj A, Duffy SW, Baldwin DR. CT screening for lung cancer: is the evidence strong enough? Lung Cancer. 2016;91:29–35.
Mauchley DC, Mitchell JD. Current estimate of costs of lung cancer screening in the United States. Thorac Surg Clin. 2015;25:205–15.
Mulshine JL, D’Amico TA. Issues with implementing a high-quality lung cancer screening program. CA Cancer J Clin. 2014;64:352–63.
Smieliauskas F, MacMahon H, Salgia R, Shih YC. Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening. J Med Screen. 2014;21:207–15.
Kamel M, Stiles B, Altorki NK. Clinical issues in the surgical management of screen-identified lung cancers. Oncology. 2015;29:944–9.
Aberle DR, DeMello S, Berg CD, et al. Results of the two incidence screenings in the national lung screening trial. N Engl J Med. 2013;369:920–31.
Black WC, Gareen IF, Soneji SS, et al. Cost-effectiveness of CT screening in the national lung screening trial. N Engl J Med. 2014;371:1793–802.
Aberle DR, Adams AM, National Lung Screening Trial Research Team, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365:395–409.
Church TR, Black WC, National Lung Screening Trial Research Team, et al. Results of initial low-dose computed tomographic screening for lung cancer. N Engl J Med. 2013;368:1980–91.
Kovalchik SA, Tammemagi M, Berg CD, et al. Targeting of low-dose CT screening according to the risk of lung-cancer death. N Engl J Med. 2013;369:245–54.
Brenner DJ, Hall EJ. Computed tomography–an increasing source of radiation exposure. N Engl J Med. 2007;357:2277–84.
ACR. ACR manual on contrast media. Version 10.1; 2015.
Nash K, Hafeez A, Hou S. Hospital-acquired renal insufficiency. Am J Kidney Dis. 2002;39:930–6.
IMV. International marketing ventures. CT market outlook report. Des Plaines, IL; 2014.
European Commission (EC). Radiation protection No. 180. Medical radiation exposure of the European population. Part 1/2. Brussels, BE: directorate-general for energy. Directorate D—nuclear safety & fuel cycle. Unit D3—radiation protection; 2014.
Kachelriess M. Iterative reconstruction techniques: what do they mean for cardiac CT? Curr Cardiovasc Imaging Rep. 2013;6:268–81.
Acknowledgment
Professor Dewey would like to thank Drs. Feger, Rief, and Zimmermann for excellent support.
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Dewey, M., Kachelrieß, M. (2018). Fundamentals of X-Ray Computed Tomography: Acquisition and Reconstruction. In: Sack, I., Schaeffter, T. (eds) Quantification of Biophysical Parameters in Medical Imaging. Springer, Cham. https://doi.org/10.1007/978-3-319-65924-4_14
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DOI: https://doi.org/10.1007/978-3-319-65924-4_14
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