Abstract
Trauma exposure is a common experience for childbearing-age women: among women over age 18 in the USA, one in three has experienced intimate partner violence, and more than 40% has experienced sexual violence during their lifetime (Breiding et al. 2014; Tjaden and Thoennes, 2000). In this chapter, we discuss associations between traumatic experiences and physiological stress system functioning among adults, with particular emphasis on the experiences of mothers and their young children. We focus on abnormalities of two interdependent physiological systems that orchestrate the stress response: the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. Dysfunction in these systems has been implicated in the development of multiple physical and psychological problems (Shonkoff et al. 2009). Importantly, stress system alterations may help explain the negative outcomes observed among children of trauma-exposed women or the intergenerational transmission of trauma. First, stress system dysfunction is likely to permeate functioning across a range of functional domains, including parenting (Leerkes et al. 2015), shaping children’s development. Second, dysregulation of stress responses can directly affect fetal development during gestation, when maternal and fetal biology are intrinsically connected, leading to increased risk for physical and psychological disease (Talge et al. 2007). Stress response alterations may be fruitful targets of interventions that seek to address the needs of trauma-exposed mothers and promote better outcomes for their offspring.
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References
Belsky J, de Haan M (2011) Annual research review: parenting and children’s brain development: the end of the beginning. J Child Psychol Psychiatry 52(4):409–428
Blanchard EB, Hickling EJ, Buckley TC, Taylor AE, Vollmer A, Loos WR (1996) Psychophysiology of posttraumatic stress disorder related to motor vehicle accidents: replication and extension. J Consult Clin Psychol 64(4):742–751
Bolten MI, Wurmser H, Buske-Kirschbaum A, Papoušek M, Pirke KM, Hellhammer D (2011) Cortisol levels in pregnancy as a psychobiological predictor for birth weight. Arch Womens Ment Health 14(1):33–41
Bremner JD, Vythilingam M, Vermetten E, Adil J, Khan S, Nazeer A, Afzal N, McGlashan T, Elzinga B, Anderson GM, Heninger G, Southwick SM, Charney DS (2003) Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology 28(6):733–750
Breiding MJ (2014) Prevalence and characteristics of sexual violence, stalking, and intimate partner violence victimization—National Intimate Partner and Sexual Violence Survey, United States, 2011. Morbidity and mortality weekly report. Surveill Summ (Washington, DC: 2002) 63(8):1
Buckley TC, Kaloupek DG (2001) A meta-analytic examination of basal cardiovascular activity in posttraumatic stress disorder. Psychosom Med 63(4):585–594
Burke JG, Lee LC, O’Campo P (2008) An exploration of maternal intimate partner violence experiences and infant general health and temperament. Matern Child Health J 12(2):172–179
Carpenter LL, Shattuck TT, Tyrka AR, Geracioti TD, Price LH (2011) Effect of childhood physical abuse on cortisol stress response. Psychopharmacology 214(1):367–375
Chida Y, Steptoe A (2009) Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis. Biol Psychol 80(3):265–278
Cohen H, Benjamin J, Geva AB, Matar MA, Kaplan Z, Kotler M (2000) Autonomic dysregulation in panic disorder and in post-traumatic stress disorder: application of power spectrum analysis of heart rate variability at rest and in response to recollection of trauma or panic attacks. Psychiatry Res 96(1):1–13
Cyranowski JM, Hofkens TL, Swartz HA, Salomon K, Gianaros PJ (2011) Cardiac vagal control in nonmedicated depressed women and nondepressed controls: impact of depression status, lifetime trauma history, and respiratory factors. Psychosom Med 73(4):336–343. doi:10.1097/PSY.0b013e318213925d
Dale LP, Carroll LE, Galen G, Hayes JA, Webb KW, Porges SW (2009) Abuse history is related to autonomic regulation to mild exercise and psychological well being. Appl Psychophysiol Biofeedback 34(4):299–308. doi:10.1007/s10484-009-9111-4
Dancause KN, Laplante DP, Oremus C, Fraser S, Brunet A, King S (2011) Disaster-related prenatal maternal stress influences birth outcomes: project ice storm. Early Hum Dev 87(12):813–820
Davis EP, Glynn LM, Schetter CD, Hobel C, Chicz-Demet A, Sandman CA (2007) Prenatal exposure to maternal depression and cortisol influences infant temperament. Journal of the American Academy of Child & Adolescent Psychiatry 46(6):737–746
Dawson ME, Schell AM, Courtney CG (2011) The skin conductance response, anticipation, and decision-making. J Neurosci Psychol Econ 4(2):111
de Weerth C, van Hees Y, Buitelaar JK (2003) Prenatal maternal cortisol levels and infant behavior during the first 5 months. Early human development 74(2):139–151
de Weerth C, Buitelaar JK, Beijers R (2013) Infant cortisol and behavioral habituation to weekly maternal separations: links with maternal prenatal cortisol and psychosocial stress. Psychoneuroendocrinology 38(12):2863–2874
Elzinga BM, Schmahl CG, Vermetten E, van Dyck R, Bremner JD (2003) Higher cortisol levels following exposure to traumatic reminders in abuse-related PTSD. Neuropsychopharmacology 28(9):1656–1665
Gonzalez A, Jenkins JM, Steiner M, Fleming AS (2012) Maternal early life experiences and parenting: the mediating role of cortisol and executive function. J Am Acad Child Adolesc Psychiatry 51(7):673–682
Griffin MG, Resick PA, Yehuda R (2005) Enhanced cortisol suppression following dexamethasone administration in domestic violence survivors. Am J Psychiatr 162(6):1192–1199
Gunnar M, Quevedo K (2007) The neurobiology of stress and development. Annu Rev Psychol 58:145–173
Gutteling BM, de Weerth C, Willemsen-Swinkels SH, Huizink AC, Mulder EJ, Visser GH, Buitelaar JK (2005) The effects of prenatal stress on temperament and problem behavior of 27-month-old toddlers. Eur Child Adolesc Psychiatry 14(1):41–51
Hauschildt M, Peters MJ, Moritz S, Jelinek L (2011) Heart rate variability in response to affective scenes in posttraumatic stress disorder. Biol Psychol 88(2):215–222
Heim C, Ehlert U, Hellhammer DH (2000) The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology 25(1):1–35
Herbert J, Goodyer IM, Grossman AB, Hastings MH, De Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR (2006) Do corticosteroids damage the brain? J Neuroendocrinol 18(6):393–411
Joosen KJ, Mesman J, Bakermans-Kranenburg MJ, Pieper S, Zeskind PS, van IJzendoorn MH (2013) Physiological reactivity to infant crying and observed maternal sensitivity. Infancy 18(3):414–431
Juul SH, Hendrix C, Robinson B, Stowe ZN, Newport DJ, Brennan PA, Johnson KC (2015) Maternal early-life trauma and affective parenting style: the mediating role of HPA-axis function. Arch Womens Ment Health:1–7
Klaassens ER, Giltay EJ, Cuijpers P, van Veen T, Zitman FG (2012) Adulthood trauma and HPA-axis functioning in healthy subjects and PTSD patients: a meta-analysis. Psychoneuroendocrinology 37(3):317–331
Leerkes EM, Supple AJ, O'Brien M, Calkins SD, Haltigan JD, Wong MS, Fortuna K (2015) Antecedents of maternal sensitivity during distressing tasks: integrating attachment, social information processing, and psychobiological perspectives. Child Dev 86(1):94–111
Levendosky AA, Bogat GA, Lonstein JS, Martinez-Torteya C, Muzik M, Granger DA, Von Eye A (2016) Infant adrenocortical reactivity and behavioral functioning: relation to early exposure to maternal intimate partner violence. Stress 19(1):37–44
Liberzon I, Abelson JL, Flagel SB, Raz J, Young EA (1999) Neuroendocrine and psychophysiologic responses in PTSD: a symptom provocation study. Neuropsychopharmacology 21(1):40–50
Liddell BJ, Kemp AH, Steel Z, Nickerson A, Bryant RA, Tam N, Tay AK, Silove D (2016) Heart rate variability and the relationship between trauma exposure age, and psychopathology in a post-conflict setting. BMC Psychiatry 16(1):1
Lin EK, Bugental DB, Turek V, Martorell GA, Olster DH (2002) Children’s vocal properties as mobilizers of stress-related physiological responses in adults. Personal Soc Psychol Bull 28(3):346–357
Martinez-Torteya C, Bogat GA, Levendosky AA, Von Eye A (2016) The influence of prenatal intimate partner violence exposure on hypothalamic–pituitary–adrenal axis reactivity and childhood internalizing and externalizing symptoms. Dev Psychopathol 28(1):55–72
Martorell GA, Bugental DB (2006) Maternal variations in stress reactivity: implications for harsh parenting practices with very young children. J Fam Psychol 20(4):641
Meewisse ML, Reitsma JB, De Vries GJ, Gersons BP, Olff M (2007) Cortisol and post-traumatic stress disorder in adults. Br J Psychiatry 191(5):387–392
Mills-Koonce WR, Propper C, Gariepy JL, Barnett M, Moore GA, Calkins S, Cox MJ (2009) Psychophysiological correlates of parenting behavior in mothers of young children. Dev Psychobiol 51(8):650–661
Morris MC, Compas BE, Garber J (2012) Relations among posttraumatic stress disorder, comorbid major depression, and HPA function: a systematic review and meta-analysis. Clin Psychol Rev 32(4):301–315
Orr SP, Solomon Z, Peri T, Pitman RK, Shalev AY (1997) Physiologic responses to loud tones in Israeli veterans of the 1973 Yom Kippur War. Biol Psychiatry 41(3):319–326
Orr SP, Lasko NB, Metzger LJ, Berry NJ, Ahern CE, Pitman RK (1998) Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse. J Consult Clin Psychol 66(6):906–913
Palma-Gudiel H, Córdova-Palomera A, Leza JC, Fañanás L (2015) Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: a critical review. Neurosci Biobehav Rev 55:520–535
Pico-Alfonso MA, Garcia-Linares MI, Celda-Navarro N, Herbert J, Martinez M (2004) Changes in cortisol and dehydroepiandrosterone in women victims of physical and psychological intimate partner violence. Biol Psychiatry 56(4):233–240
Pole N (2007) The psychophysiology of posttraumatic stress disorder: a meta-analysis. Psychol Bull 133(5):725–746
Porges SW, Furman SA (2011) The early development of the autonomic nervous system provides a neural platform for social behaviour: a polyvagal perspective. Infant Child Dev 20(1):106–118
Rash JA, Thomas JC, Campbell TS, Letourneau N, Granger DA, Giesbrecht GF (2016) Developmental origins of infant stress reactivity profiles: a multi-system approach. Dev Psychobiol 58(5):578–599
Sack M, Hopper JW, Lamprecht F (2004) Low respiratory sinus arrhythmia and prolonged psychophysiological arousal in posttraumatic stress disorder: heart rate dynamics and individual differences in arousal regulation. Biol Psychiatry 55(3):284–290
Schechter DS, Zeanah CH Jr, Myers MM, Brunelli SA, Liebowitz MR, Marshall RD, Coates SW, Trabka KA, Baca P, Hofer MA (2004) Psychobiological dysregulation in violence-exposed mothers: salivary cortisol of mothers with very young children pre-and post-separation stress. Bull Menn Clin 68(4):319
Shalev AY, Peri T, Orr SP, Bonne O, Pitman RK (1997) Auditory startle responses in help-seeking trauma survivors. Psychiatry Res 69(1):1–7
Shonkoff JP, Boyce WT, McEwen BS (2009) Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA 301(21):2252–2259
Sturge-Apple ML, Davies PT, Cicchetti D, Cummings EM (2009) The role of mothers’ and fathers’ adrenocortical reactivity in spillover between interparental conflict and parenting practices. J Fam Psychol 23(2):215
Sturge-Apple ML, Skibo MA, Rogosch FA, Ignjatovic Z, Heinzelman W (2011) The impact of allostatic load on maternal sympathovagal functioning in stressful child contexts: implications for problematic parenting. Dev Psychopathol 23(03):831–844
Susman EJ, Schmeelk KH, Ponirakis A, Gariepy JL (2001) Maternal prenatal, postpartum, and concurrent stressors and temperament in 3-year-olds: a person and variable analysis. Dev Psychopathol 13(3):629–652
Tjaden P, Thoennes N (2000) Full report of the prevalence, incidence, and consequences of violence against women: findings from the National Violence Against Women Survey (NCJ183781). U.S. Department of Justice, National Institute of Justice, Washington, DC
Talge NM, Neal C, Glover V (2007) Antenatal maternal stress and long-term effects on child neurodevelopment: how and why? J Child Psychol Psychiatry 48(3–4):245–261
Wessa M, Rohleder N, Kirschbaum C, Flor H (2006) Altered cortisol awakening response in posttraumatic stress disorder. Psychoneuroendocrinology 31(2):209–215
Xiong X, Harville EW, Mattison DR, Elkind-Hirsch K, Pridjian G, Buekens P (2008) Exposure to Hurricane Katrina, post-traumatic stress disorder and birth outcomes. Am J Med Sci 336:111–115
Yehuda R (2003) Hypothalamic–pituitary–adrenal alterations in PTSD: are they relevant to understanding cortisol alterations in cancer? Brain Behav Immun 17(1):73–83
Zucker TL, Samuelson KW, Muench F, Greenberg MA, Gevirtz RN (2009) The effects of respiratory sinus arrhythmia biofeedback on heart rate variability and posttraumatic stress disorder symptoms: a pilot study. Appl Psychophysiol Biofeedback 34(2):135–143
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Martinez-Torteya, C., D’Amico, J., Gilchrist, M. (2018). Trauma Exposure: Consequences to Maternal and Offspring Stress Systems. In: Muzik, M., Rosenblum, K. (eds) Motherhood in the Face of Trauma. Integrating Psychiatry and Primary Care. Springer, Cham. https://doi.org/10.1007/978-3-319-65724-0_6
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