Acute Kidney Injury After Liver Transplantation
Acute kidney injury after liver transplantation is a frequent complication that is caused by a multitude of perioperative renal insults often in addition to pre-existing renal insufficiency. Its definition is problematic mostly because the basis of most definitions, serum creatinine is a poor and insensitive marker of renal injury. This chapter will review the epidemiology and common causes of acute kidney injury after liver transplantation.
The incidence of postoperative renal insufficiency and acute kidney injury (AKI) in patients undergoing liver transplantation ranges from 20% up to 90%  and more than 80% of these episodes occur within the first 2 postoperative days. Earlier studies found that mortality at 30 days was 50% in patients who developed AKI and 29% in non-AKI patients . AKI necessitating renal replacement therapy has been associated with mortality rates from 55 to 90% . More recent data confirmed that AKI is associated with increased...
KeywordsRenal injury Chronic kidney disease Dialysis Renal replacement therapy Abdominal compartment syndrome Hemolytic uremic syndrome
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